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UGID:2138976     UniGene Hs.632082     Homo sapiens (human)   SLIT1
Slit homolog 1 (Drosophila) (SLIT1)

Human protein-coding gene SLIT1. Represented by 162 ESTs from 58 cDNA libraries. Corresponds to reference sequence NM_003061.2. [UniGene 2138976 - Hs.632082]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003052.2 SLIT1 gene product H. sapiens 100.0 1533
XP_003312806.1 PREDICTED: slit homolog 1 protein P. troglodytes 99.9 1593
NP_056563.2 Slit1 gene product M. musculus 96.3 1530
NP_001080578.1 slit homolog 1 precursor X. laevis 88.7 1516
NP_001030140.1 slit1a gene product D. rerio 80.5 1510
NP_001097334.1 slit, isoform E D. melanogaster 51.8 901
NP_510437.2 Protein SLT-1 C. elegans 48.5 846
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_003904113.1 PREDICTED: slit homolog 1 protein P. anubis 99.4 1533
XP_001094231.2 PREDICTED: slit homolog 1 protein M. mulatta 99.0 1610

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; thyroid; eye; thymus; mixed; blood; muscle; embryonic tissue; trachea; uterus; connective tissue; lung; kidney; pituitary gland
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q23.3-q24
UniSTS entry: Chr 10 WI-13377 [Map Viewer]
UniSTS entry: Chr 10 RH66322 [Map Viewer]
UniSTS entry: Chr 10 SLIT1
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

AB011537.3 Homo sapiens mRNA for MEGF4, partial cds P
AB017167.1 Homo sapiens mRNA for Slit-1 protein, complete cds P
AK125438.1 Homo sapiens cDNA FLJ43449 fis, clone OCBBF2032671 A
NM_003061.2 Homo sapiens slit homolog 1 (Drosophila) (SLIT1), mRNA PA
BC146761.1 Homo sapiens slit homolog 1 (Drosophila), mRNA (cDNA clone MGC:166830 IMAGE:9007200), complete cds PA
BC146851.1 Homo sapiens slit homolog 1 (Drosophila), mRNA (cDNA clone MGC:181954 IMAGE:9056779), complete cds P
BC028105.1 Homo sapiens slit homolog 1 (Drosophila), mRNA (cDNA clone IMAGE:5247200), with apparent retained intron PA
AY029183.1 Homo sapiens SLIT1 isoform B (SLIT1) mRNA, partial cds, alternatively spliced P

EST sequences (10 of 162) [Show all sequences]

AI061144.1 Clone IMAGE:1700697 kidney 3' read
AI124724.1 Clone IMAGE:1540046 brain 3' read P
AI125126.1 Clone IMAGE:1539441 brain 3' read P
BX109409.1 Clone IMAGp998B135725_;_IMAGE:2310060 uncharacterized tissue
BX116431.1 Clone IMAGp998F10166_;_IMAGE:38403 brain A
AI216643.1 Clone IMAGE:1883654 lung 3' read
T06730.1 Clone HFBDX69 brain
R35605.1 Clone IMAGE:38403 brain 5' read
AI362935.1 Clone IMAGE:2019002 brain 3' read
T08048.1 Clone HIBAB33 brain 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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