NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:2138976     UniGene Hs.632082     Homo sapiens (human)   SLIT1
Slit homolog 1 (Drosophila) (SLIT1)

Human protein-coding gene SLIT1. Represented by 162 ESTs from 58 cDNA libraries. Corresponds to reference sequence NM_003061.2. [UniGene 2138976 - Hs.632082]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003052.2 SLIT1 gene product H. sapiens 100.0 1533
XP_003312806.1 PREDICTED: slit homolog 1 protein P. troglodytes 99.9 1593
NP_056563.2 Slit1 gene product M. musculus 96.3 1530
NP_001080578.1 slit homolog 1 precursor X. laevis 88.7 1516
NP_001030140.1 slit1a gene product D. rerio 80.5 1510
NP_001097334.1 slit, isoform E D. melanogaster 51.8 901
NP_510437.2 Protein SLT-1 C. elegans 48.5 846
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_003904113.1 PREDICTED: slit homolog 1 protein P. anubis 99.4 1533
XP_001094231.2 PREDICTED: slit homolog 1 protein M. mulatta 99.0 1610

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; thyroid; eye; thymus; mixed; blood; muscle; embryonic tissue; trachea; uterus; connective tissue; lung; kidney; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q23.3-q24
UniSTS entry: Chr 10 WI-13377 [Map Viewer]
UniSTS entry: Chr 10 RH66322 [Map Viewer]
UniSTS entry: Chr 10 SLIT1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

AB011537.3 Homo sapiens mRNA for MEGF4, partial cds P
AB017167.1 Homo sapiens mRNA for Slit-1 protein, complete cds P
AK125438.1 Homo sapiens cDNA FLJ43449 fis, clone OCBBF2032671 A
NM_003061.2 Homo sapiens slit homolog 1 (Drosophila) (SLIT1), mRNA PA
BC146761.1 Homo sapiens slit homolog 1 (Drosophila), mRNA (cDNA clone MGC:166830 IMAGE:9007200), complete cds PA
BC146851.1 Homo sapiens slit homolog 1 (Drosophila), mRNA (cDNA clone MGC:181954 IMAGE:9056779), complete cds P
BC028105.1 Homo sapiens slit homolog 1 (Drosophila), mRNA (cDNA clone IMAGE:5247200), with apparent retained intron PA
AY029183.1 Homo sapiens SLIT1 isoform B (SLIT1) mRNA, partial cds, alternatively spliced P

EST sequences (10 of 162) [Show all sequences]

AI061144.1 Clone IMAGE:1700697 kidney 3' read
AI124724.1 Clone IMAGE:1540046 brain 3' read P
AI125126.1 Clone IMAGE:1539441 brain 3' read P
BX109409.1 Clone IMAGp998B135725_;_IMAGE:2310060 uncharacterized tissue
BX116431.1 Clone IMAGp998F10166_;_IMAGE:38403 brain A
AI216643.1 Clone IMAGE:1883654 lung 3' read
T06730.1 Clone HFBDX69 brain
R35605.1 Clone IMAGE:38403 brain 5' read
AI362935.1 Clone IMAGE:2019002 brain 3' read
T08048.1 Clone HIBAB33 brain 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help