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UGID:2138429     UniGene Hs.631535     Homo sapiens (human)   AKT2
V-akt murine thymoma viral oncogene homolog 2 (AKT2)

Human protein-coding gene AKT2. Represented by 763 ESTs from 291 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 2138429 - Hs.631535]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001093461.1 PREDICTED: RAC-beta serine/threonine-protein kinase isoform 6 M. mulatta 100.0 480
NP_001167450.1 AKT2 gene product P. anubis 100.0 480
XP_001143709.2 PREDICTED: RAC-beta serine/threonine-protein kinase isoform 12 P. troglodytes 100.0 480
NP_001617.1 AKT2 gene product H. sapiens 100.0 480
XP_001498801.1 PREDICTED: RAC-beta serine/threonine-protein kinase isoform 1 E. caballus 100.0 480
NP_001243708.1 RAC-beta serine/threonine-protein kinase S. scrofa 99.8 480
NP_001193075.1 RAC-beta serine/threonine-protein kinase B. taurus 99.8 480
NP_001103678.1 Akt2 gene product M. musculus 99.6 480
NP_001080091.1 RAC-beta serine/threonine-protein kinase A X. laevis 93.4 485
NP_937789.1 akt2 gene product D. rerio 92.3 478
NP_732114.1 Akt1, isoform A D. melanogaster 71.7 515
NP_001023646.1 Protein AKT-1, isoform b C. elegans 66.4 521
XP_962134.2 serine/threonine-protein kinase gad8 N. crassa 52.2 389
NP_013822.1 Ypk2p S. cerevisiae 52.1 313
XP_001693559.1 ribosomal protein S6 kinase C. reinhardtii 46.8 188
Other hits (2 of 61) [Show all]SpeciesId(%)Len(aa)
NP_058789.1 Akt2 gene product R. norvegicus 99.0 480
NP_001012340.1 AKT2 gene product C. lupus familiaris 98.8 418

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; thymus; lung; testis; mixed; eye; blood; embryonic tissue; thyroid; prostate; pancreas; intestine; esophagus; placenta; mammary gland; ovary; uncharacterized tissue; kidney; uterus; skin; spleen; trachea; connective tissue; amniotic fluid; umbilical cord; heart; lymph node; mouth; liver; cervix; pharynx; vascular; stomach; nerve; muscle; lymph; ascites; adrenal gland; bladder; bone; parathyroid; tonsil; bone marrow; ganglia; adipose tissue; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19q13.1-q13.2
UniSTS entry: Chr 19 SGC30851 [Map Viewer]
UniSTS entry: Chr 19 RH11487 [Map Viewer]
UniSTS entry: AKT2
UniSTS entry: MARC_6978-6979:992007604:1
UniSTS entry: Chr 14 RH101916
UniSTS entry: Chr 1 D10S16
UniSTS entry: Chr 14 RH69160
UniSTS entry: Chr 1 L17705
UniSTS entry: Chr 1 D1S1361
UniSTS entry: Chr 1 D1S1425
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (21)

M77198.1 Homo sapiens rac protein kinase-beta mRNA, complete cds P
AK122839.1 Homo sapiens cDNA FLJ16448 fis, clone BRAMY4000089, highly similar to RAC-beta serine/threonine protein kinase (EC 2.7.1.-) P
NM_001626.4 Homo sapiens v-akt murine thymoma viral oncogene homolog 2 (AKT2), transcript variant 1, mRNA PA
BC063421.1 Homo sapiens v-akt murine thymoma viral oncogene homolog 2, mRNA (cDNA clone IMAGE:5220341), complete cds PA
M95936.1 Human protein-serine/threonine (AKT2) mRNA, complete cds P
BC120995.1 Homo sapiens v-akt murine thymoma viral oncogene homolog 2, mRNA (cDNA clone MGC:149587 IMAGE:40116493), complete cds P
BC120994.1 Homo sapiens v-akt murine thymoma viral oncogene homolog 2, mRNA (cDNA clone MGC:149586 IMAGE:40116490), complete cds P
BC127856.1 Homo sapiens cDNA clone IMAGE:40133124
AK055779.1 Homo sapiens cDNA FLJ31217 fis, clone KIDNE2004095, highly similar to RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) P
AK054771.1 Homo sapiens cDNA FLJ30209 fis, clone BRACE2001564, highly similar to RAC-BETA SERINE/THREONINE KINASE (EC 2.7.1.-) P
BC022779.1 Homo sapiens, clone IMAGE:3902512, mRNA, partial cds A
AK314619.1 Homo sapiens cDNA, FLJ95460, Homo sapiens v-akt murine thymoma viral oncogene homolog 2 (AKT2),mRNA P
AK308906.1 Homo sapiens cDNA, FLJ98947 P
AK308006.1 Homo sapiens cDNA, FLJ97954 P
AK098099.1 Homo sapiens cDNA FLJ40780 fis, clone TRACH2005769, weakly similar to RAC-BETA SERINE/THREONINE KINASE (EC 2.7.1.-) A
AK294453.1 Homo sapiens cDNA FLJ55487 complete cds, highly similar to RAC-beta serine/threonine-protein kinase (EC2.7.11.1) P
BC032709.1 Homo sapiens v-akt murine thymoma viral oncogene homolog 2, mRNA (cDNA clone IMAGE:5496641), partial cds P
AK304209.1 Homo sapiens cDNA FLJ58721 complete cds, highly similar to RAC-beta serine/threonine-protein kinase (EC2.7.11.1) P
NM_001243028.1 Homo sapiens v-akt murine thymoma viral oncogene homolog 2 (AKT2), transcript variant 3, mRNA PA
NM_001243027.1 Homo sapiens v-akt murine thymoma viral oncogene homolog 2 (AKT2), transcript variant 2, mRNA PA
BC040028.1 Homo sapiens v-akt murine thymoma viral oncogene homolog 2, mRNA (cDNA clone IMAGE:6020864) P

EST sequences (10 of 763) [Show all sequences]

AA978295.1 Clone IMAGE:1579901 mixed 3' read P
AA904651.1 Clone IMAGE:1503935 mixed 3' read
R18201.1 Clone IMAGE:30453 brain 5' read
AI025343.1 Clone IMAGE:1643095 testis 3' read A
AI026992.1 Clone IMAGE:1649396 parathyroid 3' read P
AI028103.1 Clone IMAGE:1650348 parathyroid 3' read P
AA909715.1 Clone IMAGE:1544189 mixed 3' read P
AI038667.1 Clone IMAGE:1658731 embryonic tissue 3' read P
AI076304.1 Clone IMAGE:1673557 mixed 3' read A
AI082336.1 Clone IMAGE:1670916 uncharacterized tissue 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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