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UGID:2089552     UniGene Hs.620541     Homo sapiens (human)   EARS2
Glutamyl-tRNA synthetase 2, mitochondrial (EARS2)

Human protein-coding gene EARS2. Represented by 376 ESTs from 166 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 2089552 - Hs.620541]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001077083.1 EARS2 gene product H. sapiens 100.0 522
XP_001162700.1 PREDICTED: probable glutamate--tRNA ligase, mitochondrial isoform 6 P. troglodytes 99.8 522
NP_080416.1 Ears2 gene product M. musculus 90.4 522
NP_001038907.1 zgc:153247 gene product D. rerio 71.1 485
NP_648894.2 CG4573 D. melanogaster 58.2 481
NP_499917.2 Protein EARS-2 C. elegans 56.8 280
NP_014609.1 glutamate--tRNA ligase MSE1 S. cerevisiae 47.8 276
Other hits (2 of 44) [Show all]SpeciesId(%)Len(aa)
XP_003916723.1 PREDICTED: probable glutamate--tRNA ligase, mitochondrial P. anubis 97.1 522
XP_001094523.1 PREDICTED: probable glutamyl-tRNA synthetase, mitochondrial isoform 2 M. mulatta 96.9 522

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; skin; liver; intestine; bone marrow; heart; ovary; adrenal gland; mouth; spleen; trachea; esophagus; thymus; lung; mixed; pituitary gland; embryonic tissue; kidney; blood; placenta; uncharacterized tissue; eye; stomach; prostate; uterus; cervix; connective tissue; muscle; bladder; salivary gland; bone; thyroid; lymph node; pancreas; lymph; umbilical cord
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16p12.2
UniSTS entry: Chr 16 RH65694 [Map Viewer]
UniSTS entry: Chr 16 RH65293
UniSTS entry: Chr 16 SHGC-57880
UniSTS entry: Chr 16 WI-11144 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

BX648129.1 Homo sapiens mRNA; cDNA DKFZp686J1940 (from clone DKFZp686J1940) PA
NM_001083614.1 Homo sapiens glutamyl-tRNA synthetase 2, mitochondrial (EARS2), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA PA
AB075850.1 Homo sapiens mRNA for KIAA1970 protein P
AK095998.1 Homo sapiens cDNA FLJ38679 fis, clone KIDNE2000252, highly similar to Glutamyl tRNA synthetase P
AL832489.1 Homo sapiens mRNA; cDNA DKFZp686C2322 (from clone DKFZp686C2322) PA
BC020592.1 Homo sapiens glutamyl-tRNA synthetase 2, mitochondrial (putative), mRNA (cDNA clone IMAGE:4427967), containing frame-shift errors PA
AF088053.1 Homo sapiens full length insert cDNA clone ZD64D01 A
NR_003501.1 Homo sapiens glutamyl-tRNA synthetase 2, mitochondrial (EARS2), transcript variant 2, non-coding RNA PA
BC040013.1 Homo sapiens glutamyl-tRNA synthetase 2, mitochondrial (putative), mRNA (cDNA clone MGC:48905 IMAGE:5728326), complete cds PA

EST sequences (10 of 376) [Show all sequences]

AA992076.1 Clone IMAGE:1618945 testis 3' read
AA992546.1 Clone IMAGE:1623902 embryonic tissue 3' read
R19186.1 Clone IMAGE:129919 mixed 3' read
AI033173.1 Clone IMAGE:1654469 mixed 3' read
AI090620.1 Clone IMAGE:1692161 heart 3' read
AI097300.1 Clone IMAGE:1707223 heart 3' read
BX099414.1 Clone IMAGp998C16649_;_IMAGE:291399 skin
CB156316.1 Clone B2N807043-15-F05 brain 5' read P
AA887630.1 Clone IMAGE:1160147 intestine 3' read
AI243321.1 Clone IMAGE:1847240 mixed 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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