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UGID:2086353     UniGene Hs.617342     Homo sapiens (human)   CRX
Cone-rod homeobox (CRX)

Human protein-coding gene CRX. Represented by 75 ESTs from 19 cDNA libraries. EST representation biased toward eye; retinoblastoma; adult. Corresponds to reference sequence NM_000554.4. [UniGene 2086353 - Hs.617342]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001113415.2 PREDICTED: cone-rod homeobox protein M. mulatta 100.0 318
XP_003915850.1 PREDICTED: cone-rod homeobox protein P. anubis 100.0 318
NP_000545.1 CRX gene product H. sapiens 100.0 298
NP_031796.1 Crx gene product M. musculus 97.0 298
NP_851848.2 otx5 gene product D. rerio 63.0 288
NP_001081916.1 homeobox protein otx5-B X. laevis 62.8 289
Other hits (2 of 19) [Show all]SpeciesId(%)Len(aa)
NP_776329.1 CRX gene product B. taurus 98.0 298
NP_068627.1 Crx gene product R. norvegicus 97.7 298

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: eye [show more like this]
retinoblastoma [show more like this]
adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: eye; pineal gland; muscle; uncharacterized tissue; mixed
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19q13.3
UniSTS entry: Chr 19 G42186
UniSTS entry: RH78183
UniSTS entry: Chr 1 D8S2278
UniSTS entry: Chr 1 GDB:631813
UniSTS entry: Chr 19 G27385
UniSTS entry: Chr 1 D11S3114
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

BT007364.1 Homo sapiens cone-rod homeobox mRNA, complete cds P
NM_000554.4 Homo sapiens cone-rod homeobox (CRX), mRNA P
DQ426868.1 Homo sapiens cone-rod homeobox (CRX) mRNA, partial cds, alternatively spliced P
DQ426867.1 Homo sapiens cone-rod homeobox (CRX) mRNA, 5' UTR
EF432655.1 Homo sapiens cone-rod homeobox protein (CRX) mRNA, partial cds
BC009045.1 Homo sapiens, clone IMAGE:3871392, mRNA A
DQ340179.1 Homo sapiens CRX like homeobox 1 mRNA, complete cds P

EST sequences (10 of 75) [Show all sequences]

BX117143.1 Clone IMAGp998N15924_;_IMAGE:397262 pineal gland
AI444839.1 Clone RET1F4 eye
BX490626.1 Clone DKFZp686L0184 muscle 5' read P
AW959719.1 uncharacterized tissue
BE254470.1 Clone IMAGE:3352310 eye 5' read P
BE257531.1 Clone IMAGE:3351956 eye 5' read
BE257838.1 Clone IMAGE:3350164 eye 5' read
CV025353.1 mixed 5' read P
BE777923.1 Clone IMAGE:3866904 eye 5' read P
BE780024.1 Clone IMAGE:3871172 eye 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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