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UGID:2065525     UniGene Hs.596514     Homo sapiens (human)   ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b (ATP6V0B)

Human protein-coding gene ATP6V0B. Represented by 630 ESTs from 233 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 2065525 - Hs.596514]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001097275.1 PREDICTED: v-type proton ATPase 21 kDa proteolipid subunit isoform 2 M. mulatta 100.0 204
XP_003891801.1 PREDICTED: V-type proton ATPase 21 kDa proteolipid subunit isoform 1 P. anubis 100.0 204
NP_004038.1 ATP6V0B gene product H. sapiens 100.0 204
NP_001033127.1 ATP6V0B gene product B. taurus 100.0 204
XP_004001943.1 PREDICTED: V-type proton ATPase 21 kDa proteolipid subunit isoform 1 O. aries 100.0 204
NP_291095.1 Atp6v0b gene product M. musculus 99.5 204
XP_539645.2 PREDICTED: V-type proton ATPase 21 kDa proteolipid subunit isoform 2 C. lupus familiaris 99.5 204
XP_001916016.1 PREDICTED: v-type proton ATPase 21 kDa proteolipid subunit-like isoform 1 E. caballus 99.5 204
XP_002715201.1 PREDICTED: ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b O. cuniculus 99.5 204
NP_001087741.1 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b X. laevis 92.7 204
NP_955855.1 atp6v0b gene product D. rerio 92.2 204
NP_652010.1 vacuolar H[+] ATPase subunit PPA1-1, isoform A D. melanogaster 70.6 194
NP_495659.1 Protein VHA-4 C. elegans 66.7 213
XP_964449.1 vacuolar ATP synthase 20 kDa proteolipid subunit N. crassa 65.4 185
NP_011891.1 Vma16p S. cerevisiae 62.4 186
NP_180132.1 V-type H+-transporting ATPase 21kDa proteolipid subunit A. thaliana 59.1 175
XP_001696969.1 vacuolar proton-ATPase subunit c'' proteolipid C. reinhardtii 58.8 186
Other hits (2 of 54) [Show all]SpeciesId(%)Len(aa)
XP_003308092.1 PREDICTED: v-type proton ATPase 21 kDa proteolipid subunit-like isoform 2 P. troglodytes 99.0 203
NP_001100151.1 V-type proton ATPase 21 kDa proteolipid subunit R. norvegicus 99.0 96

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; mixed; skin; eye; bone; ascites; prostate; uncharacterized tissue; spleen; pineal gland; embryonic tissue; cervix; blood; placenta; uterus; trachea; connective tissue; pancreas; intestine; testis; stomach; kidney; lymph; pituitary gland; muscle; mammary gland; liver; heart; ovary; adrenal gland; ear; tonsil; bone marrow; pharynx; salivary gland; lymph node; parathyroid; thyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p32.3
UniSTS entry: Chr 1 HSCZOA042 [Map Viewer]
UniSTS entry: Chr 1 D1S280E
UniSTS entry: Chr 1 D1S280E
UniSTS entry: Chr 1 D1S280E
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

BT007151.1 Homo sapiens ATPase, H+ transporting, lysosomal 21kDa, V0 subunit c'' mRNA, complete cds P
NM_004047.3 Homo sapiens ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b (ATP6V0B), transcript variant 1, mRNA PA
CR456972.1 Homo sapiens full open reading frame cDNA clone RZPDo834C025D for gene ATP6V0B, ATPase, H+ transporting, lysosomal 21kDa, V0 subunit c''; complete cds, incl. stopcodon P
L05089.1 Homo sapiens ATPase homolog mRNA, partial cds
NM_001039457.1 Homo sapiens ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b (ATP6V0B), transcript variant 2, mRNA PA
BC000423.2 Homo sapiens ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b, mRNA (cDNA clone MGC:8673 IMAGE:2964510), complete cds PA
BC005876.2 Homo sapiens ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b, mRNA (cDNA clone MGC:4498 IMAGE:2964510), complete cds PA
D89052.1 Homo sapiens mRNA for proton-ATPase-like protein, complete cds P

EST sequences (10 of 630) [Show all sequences]

AA960945.1 Clone IMAGE:1569714 lung 3' read
AA971433.1 Clone IMAGE:1583210 mixed 3' read A
AA972562.1 Clone IMAGE:1584721 lung 3' read A
AA977042.1 Clone IMAGE:1586919 uncharacterized tissue 3' read A
AA985346.1 Clone IMAGE:1629456 brain 3' read P
AA992440.1 Clone IMAGE:1602673 lung 3' read A
AA996048.1 Clone IMAGE:1607126 mammary gland 3' read A
AI000269.1 Clone IMAGE:1636902 kidney 3' read A
AA903861.1 Clone IMAGE:1518769 uncharacterized tissue 3' read A
AI016232.1 Clone IMAGE:1641174 testis 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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