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UGID:2063963     UniGene Hs.594952     Homo sapiens (human)   DES
Desmin (DES)

Human protein-coding gene DES. Represented by 1418 ESTs from 228 cDNA libraries. Corresponds to reference sequence NM_001927.3. [UniGene 2063963 - Hs.594952]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001104181.1 PREDICTED: desmin-like isoform 4 M. mulatta 100.0 469
NP_001162488.1 desmin P. anubis 100.0 469
XP_526039.2 PREDICTED: desmin isoform 5 P. troglodytes 100.0 469
NP_001918.3 DES gene product H. sapiens 100.0 469
NP_001001535.1 DES gene product S. scrofa 99.6 470
NP_001075044.1 DES gene product B. taurus 99.6 469
XP_004005001.1 PREDICTED: desmin O. aries 99.6 469
NP_001012394.1 DES gene product C. lupus familiaris 99.6 468
NP_001164952.1 desmin O. cuniculus 99.6 468
NP_034173.1 Des gene product M. musculus 99.2 468
NP_001087033.1 desmin, gene 1 X. laevis 90.6 457
NP_001070920.1 desmb gene product D. rerio 81.7 473
Other hits (2 of 16) [Show all]SpeciesId(%)Len(aa)
NP_071976.1 Des gene product R. norvegicus 99.4 468
XP_001492052.2 PREDICTED: desmin-like E. caballus 99.4 468

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: heart; muscle; intestine; uterus; prostate; uncharacterized tissue; larynx; stomach; mouth; lung; placenta; kidney; embryonic tissue; adipose tissue; esophagus; testis; lymph; thyroid; eye; cervix; brain; ascites; connective tissue; liver; nerve; mammary gland; umbilical cord; mixed; skin; pharynx; bladder; bone marrow; blood; pancreas; ovary; bone; peritoneum; trachea; ganglia; vascular; epididymis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q35
UniSTS entry: Chr 2 RH67933 [Map Viewer]
UniSTS entry: Chr 2 STS-W67447
UniSTS entry: Chr 2 G15847
UniSTS entry: Chr 2 REN52755
UniSTS entry: Chr 2 PMC209322P1
UniSTS entry: Chr 2 REN52787
UniSTS entry: Chr 2 G67372
UniSTS entry: Chr 2 REN52786
UniSTS entry: Vim
UniSTS entry: Chr 2 D2S1596E
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (25)

AF055081.1 Homo sapiens family CSM1 mutant desmin mRNA, allele 1, complete cds P
AF055082.1 Homo sapiens family CSM2 mutant desmin mRNA, allele 1, complete cds P
AF055083.1 Homo sapiens family CSM2 mutant desmin mRNA, allele 2, complete cds P
AK123787.1 Homo sapiens cDNA FLJ41793 fis, clone NESOP2002418, highly similar to DESMIN P
NM_001927.3 Homo sapiens desmin (DES), mRNA PA
AF137053.1 Homo sapiens mutant desmin (MUTDESM) mRNA, MUTDESM-1 allele, complete cds P
DQ104337.1 Homo sapiens mutant desmin mRNA, complete cds P
DQ104336.1 Homo sapiens mutant desmin mRNA, complete cds P
DQ104335.1 Homo sapiens mutant desmin mRNA, complete cds P
AK022087.1 Homo sapiens cDNA FLJ12025 fis, clone HEMBB1001802, highly similar to Human desmin mRNA P
AF167579.1 Homo sapiens mutant desmin mRNA, complete cds P
EF617312.1 Homo sapiens mutant desmin mRNA, complete cds P
U59167.1 Human desmin mRNA, complete cds P
AY083345.1 Homo sapiens mutant desmin mRNA, complete cds P
AF487828.1 Homo sapiens mutant desmin mRNA, complete cds P
AF486807.1 Homo sapiens mutant desmin mRNA, complete cds P
BC032116.2 Homo sapiens desmin, mRNA (cDNA clone MGC:29582 IMAGE:4905678), complete cds PA
AK098332.1 Homo sapiens cDNA FLJ41013 fis, clone UTERU2018609, highly similar to DESMIN P
AK097038.1 Homo sapiens cDNA FLJ39719 fis, clone SMINT2013890, highly similar to DESMIN P
AY125465.1 Homo sapiens mutant desmin mRNA, complete cds P
AK300654.1 Homo sapiens cDNA FLJ61414 complete cds, highly similar to Desmin P
BC010072.2 Homo sapiens desmin, mRNA (cDNA clone IMAGE:4131519) PA
AF521879.1 Homo sapiens mutant desmin mRNA, complete cds P
AF527578.1 Homo sapiens mutant desmin mRNA, complete cds P
JX114780.1 Homo sapiens mutant desmin p.K241E (DES) mRNA, complete cds

EST sequences (10 of 1418) [Show all sequences]

AA954847.1 Clone IMAGE:1574347 kidney 3' read A
AA838405.1 Clone IMAGE:1422549 kidney
AI052564.1 Clone IMAGE:1653393 mixed 3' read
CA976173.1 Clone IMAGE:6202596 nerve 5' read P
AI123083.1 Clone IMAGE:1510011 mixed 3' read A
AI125917.1 Clone IMAGE:1712202 uterus 3' read A
AI140554.1 Clone IMAGE:1653481 mixed 3' read A
AI142240.1 Clone IMAGE:1839737 testis 5' read
CB047987.1 Clone IMAGE:3270471 prostate 3' read A
CB047988.1 Clone IMAGE:3270471 prostate 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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