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UGID:2060529     UniGene Hs.591518     Homo sapiens (human)   KDM1A
Lysine (K)-specific demethylase 1A (KDM1A)

Human protein-coding gene KDM1A. Represented by 519 ESTs from 235 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 2060529 - Hs.591518]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001252568.1 lysine (K)-specific demethylase 1A M. mulatta 100.0 875
XP_003891348.1 PREDICTED: lysine-specific histone demethylase 1A isoform 2 P. anubis 100.0 875
NP_001009999.1 KDM1A gene product H. sapiens 100.0 875
XP_513190.3 PREDICTED: lysine-specific histone demethylase 1A P. troglodytes 100.0 729
XP_001501516.2 PREDICTED: lysine-specific histone demethylase 1A E. caballus 100.0 729
XP_535366.2 PREDICTED: lysine-specific histone demethylase 1A isoform 1 C. lupus familiaris 99.9 876
XP_002703793.1 PREDICTED: lysine-specific histone demethylase 1A isoform 1 B. taurus 99.9 876
NP_001123570.1 Kdm1a gene product R. norvegicus 99.8 871
NP_598633.2 Kdm1a gene product M. musculus 99.7 852
NP_001106157.1 KDM1A gene product S. scrofa 99.5 872
NP_001229924.1 lysine-specific histone demethylase 1A D. rerio 94.8 823
NP_649194.1 suppressor of variegation 3-3, isoform A D. melanogaster 67.6 802
NP_187981.1 Lysine-specific histone demethylase 1-2 A. thaliana 46.3 287
Other hits (2 of 39) [Show all]SpeciesId(%)Len(aa)
XP_002194853.1 PREDICTED: lysine-specific histone demethylase 1A T. guttata 99.3 758
XP_004005566.1 PREDICTED: lysine-specific histone demethylase 1A O. aries 99.1 795

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; embryonic tissue; mammary gland; mixed; uterus; eye; prostate; heart; uncharacterized tissue; lung; intestine; placenta; mouth; liver; stomach; thyroid; bladder; pancreas; skin; kidney; ovary; cervix; pharynx; bone; pineal gland; adrenal gland; lymph; tonsil; salivary gland; larynx; ascites; parathyroid; connective tissue; blood; lymph node; pituitary gland; thymus; nerve; esophagus; muscle; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p36.12
UniSTS entry: Chr 5 RH63847
UniSTS entry: Chr 1 RH69757
UniSTS entry: Chr 1 SHGC-33968 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

BC048134.1 Homo sapiens amine oxidase (flavin containing) domain 2, mRNA (cDNA clone MGC:57494 IMAGE:5298150), complete cds PA
NM_015013.3 Homo sapiens lysine (K)-specific demethylase 1A (KDM1A), transcript variant 2, mRNA PA
NM_001009999.2 Homo sapiens lysine (K)-specific demethylase 1A (KDM1A), transcript variant 1, mRNA PA
BC016639.1 Homo sapiens amine oxidase (flavin containing) domain 2, mRNA (cDNA clone IMAGE:3917412), partial cds PA
AK290328.1 Homo sapiens cDNA FLJ75083 complete cds, highly similar to Homo sapiens amine oxidase (flavin containing) domain 2 (AOF2),mRNA PA
BC025362.1 Homo sapiens amine oxidase (flavin containing) domain 2, mRNA (cDNA clone IMAGE:5013430), partial cds PA
AL833812.1 Homo sapiens mRNA; cDNA DKFZp564P133 (from clone DKFZp564P133) PA
BC040194.2 Homo sapiens amine oxidase (flavin containing) domain 2, mRNA (cDNA clone MGC:42279 IMAGE:4815528), complete cds PA
AB011173.1 Homo sapiens mRNA for KIAA0601 protein, partial cds P

EST sequences (10 of 519) [Show all sequences]

R15766.1 Clone IMAGE:53259 brain 3' read A
R16270.1 Clone IMAGE:53259 brain 5' read P
R16404.1 Clone IMAGE:129298 mixed 5' read
AA992902.1 Clone IMAGE:1624205 embryonic tissue 3' read A
R17788.1 Clone IMAGE:30903 brain 5' read P
AI015429.1 Clone IMAGE:1618405 testis 3' read A
AI038533.1 Clone IMAGE:1658632 embryonic tissue 3' read A
AI049843.1 Clone IMAGE:1699326 kidney 3' read A
R20399.1 Clone IMAGE:32674 brain 5' read P
AI088198.1 Clone IMAGE:1683325 parathyroid 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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