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UGID:2059930     UniGene Hs.590919     Homo sapiens (human)   ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3 (ADAMTS3)

Human protein-coding gene ADAMTS3. Represented by 32 ESTs from 23 cDNA libraries. Corresponds to reference sequence NM_014243.2. [UniGene 2059930 - Hs.590919]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_055058.2 ADAMTS3 gene product H. sapiens 100.0 1204
XP_517240.2 PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform 2 P. troglodytes 99.8 1204
NP_001074870.1 a disintegrin-like and metalloprotease with thrombospondin type 1 motif, 3 isoform 2 precursor M. musculus 92.7 1202
XP_697234.5 PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 3 D. rerio 79.9 1134
Other hits (2 of 22) [Show all]SpeciesId(%)Len(aa)
XP_001104686.2 PREDICTED: a disintegrin and metalloproteinase with thrombospondin motifs 3 M. mulatta 99.2 1036
XP_003898834.1 PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 3-like, partial P. anubis 98.9 984

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; testis; embryonic tissue; mammary gland; liver; adrenal gland; muscle; blood; lung
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q13.3
UniSTS entry: Chr 4 G33602
UniSTS entry: Chr 4 HSC2JD032 [Map Viewer]
UniSTS entry: Chr 4 SHGC-67364 [Map Viewer]
UniSTS entry: Chr 4 SHGC-59735 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

AF247668.1 Homo sapiens a disintegrin-like and metalloprotease domain with thrombospondin type I motifs 3 (ADAMTS3) mRNA, partial cds P
BC130287.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 3, mRNA (cDNA clone MGC:163159 IMAGE:40146318), complete cds P
BC132735.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 3, mRNA (cDNA clone MGC:164366 IMAGE:40146757), complete cds P
BC016451.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 3, mRNA (cDNA clone IMAGE:3451933), partial cds PA
NM_014243.2 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 3 (ADAMTS3), mRNA PA
BC019707.1 Homo sapiens cDNA clone IMAGE:4707162, containing frame-shift errors PA
AK295131.1 Homo sapiens cDNA FLJ52262 complete cds, highly similar to ADAMTS-3 precursor (EC 3.4.24.-) (Adisintegrin and metalloproteinase with thrombospondin motifs 3) P
AB002364.1 Homo sapiens mRNA for KIAA0366 gene, partial cds P

EST sequences (10 of 32) [Show all sequences]

BX108558.1 Clone IMAGp998J191783_;_IMAGE:727026 testis
CB161006.1 Clone L18POOL1n1-24-E04 liver 5' read
CB161309.1 Clone L18POOL1n1-38-B01 liver 5' read P
AI382295.1 Clone IMAGE:2049492 embryonic tissue 3' read A
BX279756.1 Clone IMAGp998H2211416_;_IMAGE:5167557 brain P
CD515298.1 Clone IMAGE:30408099 brain 5' read P
F07832.1 Clone c-2jd03 brain
Z45214.1 Clone c-2jg02 brain
F04104.1 Clone c-2jg02 brain 3' read A
H01124.1 Clone IMAGE:150258 placenta 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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