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UGID:1774136     UniGene Hs.558334     Homo sapiens (human)   GRIN1
Glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1)

Human protein-coding gene GRIN1. Represented by 90 ESTs from 41 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 1774136 - Hs.558334]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003911065.1 PREDICTED: glutamate [NMDA] receptor subunit zeta-1 isoform 3 P. anubis 100.0 942
NP_001172019.1 GRIN1 gene product H. sapiens 100.0 942
NP_001008717.1 GRIN1 gene product C. lupus familiaris 99.9 921
NP_001257535.1 glutamate [NMDA] receptor subunit zeta-1 isoform 3b precursor R. norvegicus 99.7 942
NP_032195.1 Grin1 gene product M. musculus 99.7 937
XP_001117773.1 PREDICTED: glutamate [NMDA] receptor subunit zeta-1 M. mulatta 99.6 779
NP_001081615.1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 isoform 1 precursor X. laevis 96.0 903
NP_001137603.1 glutamate receptor, ionotropic, N-methyl D-aspartate 1b precursor D. rerio 94.1 936
NP_730940.1 NMDA receptor 1 D. melanogaster 58.8 956
NP_495033.2 Protein NMR-1 C. elegans 54.7 349
Other hits (2 of 30) [Show all]SpeciesId(%)Len(aa)
XP_001917547.2 PREDICTED: LOW QUALITY PROTEIN: glutamate [NMDA] receptor subunit zeta-1 E. caballus 99.5 911
XP_002691748.2 PREDICTED: glutamate [NMDA] receptor subunit zeta-1 B. taurus 99.1 922

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; eye; pancreas; mixed; ovary; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9q34.3
UniSTS entry: GDB:451867
UniSTS entry: Grin1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

D13515.1 Homo sapiens mRNA for key subunit of N-methyl-D-aspartate receptor, complete cds P
L13266.1 Homo sapiens N-methyl-d-aspartate receptor (NR1-1) mRNA, complete cds P
L13267.1 Homo sapiens N-methyl-d-aspartate receptor (NR1-2) mRNA, 3' end P
L13268.1 Homo sapiens N-methyl-d-aspartate receptor (NR1-3) mRNA, 3' end P
NM_000832.6 Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1), transcript variant NR1-1, mRNA P
AB208999.1 Homo sapiens mRNA for NMDA receptor 1 isoform NR1-2 precursor variant protein P
AB208918.1 Homo sapiens mRNA for NMDA receptor 1 isoform NR1-2 precursor variant protein P
NM_007327.3 Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1), transcript variant NR1-3, mRNA P
NM_021569.3 Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1), transcript variant NR1-2, mRNA P
U08106.1 Human N-methyl-D-aspartate receptor subunit splice variant hNR1-4 (GRIN1) mRNA, partial cds P
S57708.1 N-methyl-D-aspartate glutamate receptor channel [human, teratocarcinoma line NT2, mRNA Partial, 304 nt] P
U08107.1 Human N-methyl-D-aspartate receptor subunit splice variant hNR1N (GRIN1) mRNA, partial cds P
NM_001185091.1 Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1), transcript variant 5, mRNA P
NM_001185090.1 Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1), transcript variant NR1-4, mRNA P
L05666.1 Homo sapiens NMDA receptor subunit (NR1) mRNA, complete cds P
AF015730.1 Homo sapiens NMDAR1 subunit isoform 3b (hNMDAR1-3b) mRNA, complete cds P
AF015731.1 Homo sapiens NMDAR1 subunit isoform 4b (hNMDAR1-4b) mRNA, complete cds P

EST sequences (10 of 90) [Show all sequences]

AI014351.1 Clone IMAGE:1539123 brain 3' read
R18939.1 Clone IMAGE:33289 brain 5' read
AI124765.1 Clone IMAGE:1540102 brain 3' read P
BX114532.1 Clone IMAGp998D22296_;_IMAGE:166245 brain P
CB154737.1 Clone B2N807043-24-B07 brain 5' read P
T08653.1 Clone HIBBH74 brain 5' read
BX410287.1 Clone CS0DN004YG15 brain 5' read P
AI964054.1 Clone IMAGE:2514549 uncharacterized tissue 3' read
BX463601.2 Clone CS0DN004YG15 brain 5' read P
AL118662.1 Clone DKFZp761I1210 brain 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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