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UGID:1448002     UniGene Hs.550906     Homo sapiens (human)   KLHL28
Kelch-like family member 28 (KLHL28)

Human protein-coding gene KLHL28. Represented by 146 ESTs from 96 cDNA libraries. Corresponds to reference sequence NM_017658.3. [UniGene 1448002 - Hs.550906]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_060128.2 KLHL28 gene product H. sapiens 100.0 570
XP_001095364.1 PREDICTED: kelch-like protein 28 isoform 3 M. mulatta 99.8 570
XP_003901795.1 PREDICTED: kelch-like protein 28 P. anubis 99.8 570
XP_003314349.2 PREDICTED: LOW QUALITY PROTEIN: kelch-like protein 28 P. troglodytes 99.7 584
NP_079983.1 kelch-like protein 28 M. musculus 97.9 570
XP_002667719.2 PREDICTED: kelch-like protein 28-like D. rerio 84.7 481
NP_001086544.1 kelch-like protein 20 X. laevis 46.8 552
NP_524989.2 diablo, isoform A D. melanogaster 45.8 549
Other hits (2 of 32) [Show all]SpeciesId(%)Len(aa)
XP_547790.2 PREDICTED: kelch-like protein 28 isoform 1 C. lupus familiaris 99.3 570
XP_001493342.1 PREDICTED: kelch-like protein 28 isoform 1 E. caballus 99.3 570

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; placenta; uncharacterized tissue; stomach; eye; bladder; adrenal gland; mouth; embryonic tissue; pharynx; intestine; esophagus; testis; mammary gland; uterus; muscle; liver; kidney; trachea; prostate; connective tissue; spleen; pancreas; thyroid; vascular; lymph node; skin; bone marrow; cervix; blood; adipose tissue; bone
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 14
Map position: 14q21.2
UniSTS entry: Chr 14 RH102616
UniSTS entry: Chr 14 BTBD5_9825
UniSTS entry: Chr 1 D16S325
UniSTS entry: D14S662E
UniSTS entry: Chr 1 D15S1477
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

BC057794.1 Homo sapiens cDNA clone IMAGE:5295395, containing frame-shift errors PA
NM_017658.3 Homo sapiens kelch-like family member 28 (KLHL28), mRNA PA
BC121009.1 Homo sapiens kelch-like 28 (Drosophila), mRNA (cDNA clone MGC:149636 IMAGE:40116967), complete cds P
BC121010.1 Homo sapiens kelch-like 28 (Drosophila), mRNA (cDNA clone MGC:149637 IMAGE:40116970), complete cds P
AK289855.1 Homo sapiens cDNA FLJ76338 complete cds, highly similar to Homo sapiens BTB (POZ) domain containing 5 (BTBD5), mRNA P
AK090972.1 Homo sapiens cDNA FLJ33653 fis, clone BRAMY2024715
BC012473.2 Homo sapiens cDNA clone IMAGE:4453077, containing frame-shift errors PA

EST sequences (10 of 146) [Show all sequences]

BX118266.1 Clone IMAGp998P20601_;_IMAGE:273283 skin P
AI219490.1 Clone IMAGE:1845087 mixed 3' read PA
AI246251.1 Clone IMAGE:1857947 mixed 3' read
AI247249.1 Clone IMAGE:1863859 kidney 3' read
AI754011.1 Clone HBMSC_cr18e10 bone marrow 3' read A
Z28921.1 Clone C1A11 muscle
Z25327.1 Clone C1A11 muscle
CB958600.1 Clone IMAGE:30354070 mixed 5' read
CB999108.1 Clone IMAGE:30324560 mixed 5' read A
BX461237.2 Clone CS0DF024YM21 brain 5' read P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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