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UGID:131691     UniGene Hs.5462     Homo sapiens (human)   SLC4A4
Solute carrier family 4, sodium bicarbonate cotransporter, member 4 (SLC4A4)

Human protein-coding gene SLC4A4. Represented by 317 ESTs from 102 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 131691 - Hs.5462]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003310391.1 PREDICTED: electrogenic sodium bicarbonate cotransporter 1 isoform 1 P. troglodytes 100.0 1093
NP_001128214.1 SLC4A4 gene product H. sapiens 100.0 1093
XP_003898839.1 PREDICTED: electrogenic sodium bicarbonate cotransporter 1 isoform 2 P. anubis 99.5 1093
NP_001129732.1 electrogenic sodium bicarbonate cotransporter 1 isoform b M. musculus 98.1 1093
NP_001030156.1 slc4a4a gene product D. rerio 88.3 1077
NP_001084922.1 solute carrier family 4, sodium bicarbonate cotransporter, member 7 X. laevis 62.0 1018
NP_723264.1 Na[+]-driven anion exchanger 1, isoform B D. melanogaster 53.4 1014
NP_492258.1 Protein ABTS-1, isoform a C. elegans 51.4 1023
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_001104906.1 PREDICTED: electrogenic sodium bicarbonate cotransporter 1-like M. mulatta 98.6 1078
XP_004009946.1 PREDICTED: electrogenic sodium bicarbonate cotransporter 1 isoform 2 O. aries 98.5 1093

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; kidney; prostate; pancreas; liver; mixed; stomach; uncharacterized tissue; vascular; intestine; ovary; embryonic tissue; muscle; bone marrow; trachea; amniotic fluid; skin; bladder; heart; thyroid; spleen; eye; nerve; lung; spinal cord; connective tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q21
UniSTS entry: Chr 4 SLC4A4_3914
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (20)

AF011390.1 Homo sapiens pancreas sodium bicarbonate cotransporter mRNA, complete cds P
NM_003759.3 Homo sapiens solute carrier family 4, sodium bicarbonate cotransporter, member 4 (SLC4A4), transcript variant 2, mRNA PA
CR749482.1 Homo sapiens mRNA; cDNA DKFZp781H1314 (from clone DKFZp781H1314) PA
AF004813.1 Homo sapiens electrogenic Na+ bicarbonate cotransporter (NBC) mRNA, partial cds P
AF053753.1 Homo sapiens electrogenic Na+ bicarbonate cotransporter (NBC) mRNA, complete cds P
AF053754.1 Homo sapiens electrogenic Na+ bicarbonate cotransporter form 2 (NBC) mRNA, complete cds P
AF069510.1 Homo sapiens sodium bicarbonate cotransporter (NBC) mRNA, complete cds P
AF157492.1 Homo sapiens sodium bicarbonate cotransporter NBC1 (SLC4A4) mRNA, alternatively spliced product, complete cds P
AF310248.1 Homo sapiens sodium bicarbonate cotransporter mRNA, complete cds P
AK226164.1 Homo sapiens mRNA for solute carrier family 4, sodium bicarbonate cotransporter, member 4 variant, clone: pf04944 P
BC127908.1 Homo sapiens cDNA clone IMAGE:40132586 P
EF531618.1 Homo sapiens solute carrier family 4 sodium bicarbonate cotransporter member 4 variant C (SLC4A4) mRNA, complete cds P
NM_001098484.2 Homo sapiens solute carrier family 4, sodium bicarbonate cotransporter, member 4 (SLC4A4), transcript variant 1, mRNA PA
AK308038.1 Homo sapiens cDNA, FLJ97986 P
AK307594.1 Homo sapiens cDNA, FLJ97542 P
BC030977.1 Homo sapiens solute carrier family 4, sodium bicarbonate cotransporter, member 4, mRNA (cDNA clone MGC:32627 IMAGE:4610968), complete cds PA
AK090968.1 Homo sapiens cDNA FLJ33649 fis, clone BRAMY2024497 A
NM_001134742.1 Homo sapiens solute carrier family 4, sodium bicarbonate cotransporter, member 4 (SLC4A4), transcript variant 3, mRNA PA
AB470072.1 Homo sapiens SLC4A4 mRNA for solute carrier family 4, sodium bicarbonate cotransporter, member 4, brain type, complete cds P
AF007216.1 Homo sapiens sodium bicarbonate cotransporter (HNBC1) mRNA, complete cds P

EST sequences (10 of 317) [Show all sequences]

AA972396.1 Clone IMAGE:1584112 mixed 3' read A
AA993822.1 Clone IMAGE:1624345 embryonic tissue 5' read
R17181.1 Clone IMAGE:31819 brain 5' read
AI002821.1 Clone IMAGE:1684172 brain 3' read A
R19667.1 Clone IMAGE:34973 brain 5' read
CB047177.1 Clone IMAGE:3253186 kidney 3' read A
CB047178.1 Clone IMAGE:3253186 kidney 5' read
CB069926.1 Clone IMAGE:6553891 pancreas 5' read
BX102681.1 Clone IMAGp998O1470_;_IMAGE:22045 brain A
AI167189.1 Clone IMAGE:1509166 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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