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UGID:1371612     UniGene Hs.535298     Homo sapiens (human)   PARG
Poly (ADP-ribose) glycohydrolase (PARG)

Human protein-coding gene PARG. Represented by 96 ESTs from 64 cDNA libraries. [UniGene 1371612 - Hs.535298]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003622.2 PARG gene product H. sapiens 99.9 975
XP_003318008.1 PREDICTED: poly(ADP-ribose) glycohydrolase P. troglodytes 99.5 975
NP_036090.2 Parg gene product M. musculus 90.0 887
NP_001089602.1 poly (ADP-ribose) glycohydrolase X. laevis 80.0 515
XP_687541.4 PREDICTED: poly(ADP-ribose) glycohydrolase-like D. rerio 71.7 512
NP_001245511.1 Poly(ADP-ribose) glycohydrolase, isoform B D. melanogaster 53.9 321
Other hits (2 of 38) [Show all]SpeciesId(%)Len(aa)
XP_003903660.1 PREDICTED: poly(ADP-ribose) glycohydrolase isoform 4 P. anubis 98.2 867
XP_001104841.1 PREDICTED: poly(ADP-ribose) glycohydrolase isoform 2 M. mulatta 98.1 867

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; lymph node; embryonic tissue; liver; prostate; mammary gland; larynx; ovary; uterus; mouth; salivary gland; connective tissue; eye; pituitary gland; stomach; mixed; kidney; lung; testis; placenta; intestine; ascites; ganglia; heart; bone
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q11.23
UniSTS entry: Chr 10 RH69997 [Map Viewer]
UniSTS entry: Chr 10 RH78530 [Map Viewer]
UniSTS entry: Chr 10 PARG_8819
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

EF382674.1 Homo sapiens poly(ADP-ribose) glycohydrolase 60 kDa isoform precursor (PARG) mRNA, complete cds, alternatively spliced PA
AK301845.1 Homo sapiens cDNA FLJ54459 complete cds, highly similar to Poly(ADP-ribose) glycohydrolase (EC P
AK295244.1 Homo sapiens cDNA FLJ60257 complete cds, highly similar to Poly(ADP-ribose) glycohydrolase (EC P
BC012005.1 Homo sapiens poly (ADP-ribose) glycohydrolase, mRNA (cDNA clone IMAGE:3852747), with apparent retained intron PA
AF085828.1 Homo sapiens full length insert cDNA clone YI39B12 A
JQ890226.1 Homo sapiens mitochondrial poly(ADP-ribose) glycohydrolase (PARG) mRNA, complete cds, alternatively spliced; nuclear gene for mitochondrial product PA

EST sequences (10 of 96) [Show all sequences]

R14077.1 Clone IMAGE:27409 brain 5' read P
BX098344.1 Clone IMAGp998F23616_;_IMAGE:278806 brain P
CB144683.1 Clone L11SNU354s1-28-F08 liver 5' read
AI276875.1 Clone IMAGE:1892100 placenta 3' read A
AI278443.1 Clone IMAGE:1892451 placenta 3' read A
AI378028.1 Clone IMAGE:2091794 mixed 3' read A
R41887.1 Clone IMAGE:30862 brain 3' read A
R40204.1 Clone IMAGE:27409 brain 3' read A
AI652476.1 Clone IMAGE:2307103 uncharacterized tissue 3' read A
AI720897.1 Clone IMAGE:2334252 intestine 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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