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UGID:1293045     UniGene Hs.533670     Homo sapiens (human)   LGI1
Leucine-rich, glioma inactivated 1 (LGI1)

Human protein-coding gene LGI1. Represented by 172 ESTs from 52 cDNA libraries. Corresponds to reference sequence NM_005097.2. [UniGene 1293045 - Hs.533670]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001093284.1 PREDICTED: leucine-rich glioma-inactivated protein 1 isoform 2 M. mulatta 100.0 556
XP_003904065.1 PREDICTED: leucine-rich glioma-inactivated protein 1 P. anubis 100.0 556
NP_001065246.1 LGI1 gene product P. troglodytes 100.0 556
NP_005088.1 LGI1 gene product H. sapiens 100.0 556
XP_534971.2 PREDICTED: leucine-rich glioma-inactivated protein 1 isoform 2 C. lupus familiaris 99.6 556
NP_064674.1 leucine-rich glioma-inactivated protein 1 precursor M. musculus 98.6 556
NP_001122241.1 lgi1b gene product D. rerio 72.4 542
Other hits (2 of 17) [Show all]SpeciesId(%)Len(aa)
XP_004020092.1 PREDICTED: leucine-rich glioma-inactivated protein 1 isoform 1 O. aries 99.3 556
XP_002718563.1 PREDICTED: leucine-rich, glioma inactivated 1 O. cuniculus 99.1 556

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; kidney; umbilical cord; embryonic tissue; uncharacterized tissue; muscle; mixed; vascular; thymus; testis; trachea; intestine; eye; nerve; ganglia
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q24
UniSTS entry: Chr 10 T15408
UniSTS entry: Chr 10 WI-16274 [Map Viewer]
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

AF055636.1 Homo sapiens leucine-rich glioma-inactivated protein precursor (LGI1) mRNA, complete cds P
AY358885.1 Homo sapiens clone DNA68882 LGI1 (UNQ775) mRNA, complete cds P
NM_005097.2 Homo sapiens leucine-rich, glioma inactivated 1 (LGI1), mRNA PA
AB209408.1 Homo sapiens mRNA for leucine-rich, glioma inactivated 1 precursor variant protein P
BC022500.1 Homo sapiens leucine-rich, glioma inactivated 1, mRNA (cDNA clone MGC:26441 IMAGE:4811956), complete cds PA
AK289706.1 Homo sapiens cDNA FLJ75578 complete cds, highly similar to Homo sapiens leucine-rich, glioma inactivated 1 (LGI1), mRNA PA
AK309416.1 Homo sapiens cDNA, FLJ99457 P
AF473548.1 Homo sapiens leucine-rich glioma inactivated-1 (LGI1) mRNA, complete cds; alternatively spliced P
AK303956.1 Homo sapiens cDNA FLJ50946 complete cds, highly similar to Leucine-rich glioma-inactivated protein 1 precursor P

EST sequences (10 of 172) [Show all sequences]

R14994.1 Clone IMAGE:35825 brain 5' read
AA992136.1 Clone IMAGE:1622084 embryonic tissue 3' read A
AA992473.1 Clone IMAGE:1621910 embryonic tissue 3' read A
AI039940.1 Clone IMAGE:1659686 embryonic tissue 3' read A
AI240096.1 Clone IMAGE:1847573 mixed 3' read A
AI621238.1 Clone IMAGE:2237279 uncharacterized tissue 3' read A
R45685.1 Clone IMAGE:35825 brain 3' read A
R44821.1 Clone IMAGE:33948 brain 3' read A
AI802297.1 Clone IMAGE:2066226 embryonic tissue 3' read A
AI918747.1 Clone IMAGE:2238319 uncharacterized tissue 3' read PA

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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