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UGID:1096956     UniGene Hs.528006     Homo sapiens (human)   SPHK2
Sphingosine kinase 2 (SPHK2)

Human protein-coding gene SPHK2. Represented by 393 ESTs from 169 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 1096956 - Hs.528006]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_064511.2 SPHK2 gene product H. sapiens 100.0 653
XP_001171404.2 PREDICTED: sphingosine kinase 2 isoform 8 P. troglodytes 99.5 624
NP_001166032.1 Sphk2 gene product M. musculus 87.9 612
XP_003200262.1 PREDICTED: sphingosine kinase 2-like D. rerio 67.7 714
NP_001088560.1 sphingosine kinase 1 X. laevis 53.3 291
Other hits (2 of 23) [Show all]SpeciesId(%)Len(aa)
XP_001113908.1 PREDICTED: sphingosine kinase 2-like isoform 3 M. mulatta 98.3 652
XP_003915879.1 PREDICTED: sphingosine kinase 2 isoform 1 P. anubis 98.3 652

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; lung; eye; bladder; larynx; adrenal gland; skin; mammary gland; lymph; pancreas; thyroid; kidney; spleen; blood; liver; lymph node; mouth; intestine; cervix; heart; thymus; uncharacterized tissue; mixed; uterus; embryonic tissue; prostate; pituitary gland; trachea; ovary; placenta; connective tissue; muscle; ascites; bone marrow; stomach; vascular; nerve; ganglia; tonsil; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19q13.2
UniSTS entry: Chr 19 RH47213 [Map Viewer]
UniSTS entry: Chr 19 RH75877
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

AK122735.1 Homo sapiens cDNA FLJ16251 fis, clone HLUNG2013784, highly similar to Sphingosine kinase 2 (EC 2.7.1.-) P
NM_020126.4 Homo sapiens sphingosine kinase 2 (SPHK2), transcript variant 1, mRNA PA
AF245447.1 Homo sapiens sphingosine kinase type 2 isoform mRNA, complete cds P
AL136701.1 Homo sapiens mRNA; cDNA DKFZp564M0682 (from clone DKFZp564M0682) PA
BC006161.1 Homo sapiens sphingosine kinase 2, mRNA (cDNA clone MGC:13202 IMAGE:3677636), complete cds PA
EF107108.1 Homo sapiens sphingosine kinase-2 variant (SPHK2) mRNA, complete cds PA
BC010671.1 Homo sapiens sphingosine kinase 2, mRNA (cDNA clone MGC:16936 IMAGE:3870258), complete cds PA
AK300541.1 Homo sapiens cDNA FLJ59429 complete cds, highly similar to Sphingosine kinase 2 (EC 2.7.1.-) P
AK000599.1 Homo sapiens cDNA FLJ20592 fis, clone KAT08989 PA
AK297787.1 Homo sapiens cDNA FLJ55229 complete cds, highly similar to Sphingosine kinase 2 (EC 2.7.1.-) P
NM_001204159.2 Homo sapiens sphingosine kinase 2 (SPHK2), transcript variant 3, mRNA PA
NM_001204160.2 Homo sapiens sphingosine kinase 2 (SPHK2), transcript variant 4, mRNA PA
NM_001204158.2 Homo sapiens sphingosine kinase 2 (SPHK2), transcript variant 2, mRNA PA
NM_001243876.1 Homo sapiens sphingosine kinase 2 (SPHK2), transcript variant 5, mRNA PA
D28468.1 Homo sapiens TAXREB302 mRNA for tax-responsive element-binding protein, partial cds P

EST sequences (10 of 393) [Show all sequences]

AI089456.1 Clone IMAGE:1695447 uterus 3' read A
CB049588.1 Clone IMAGE:3271502 prostate 3' read A
AI184921.1 Clone IMAGE:1509105 mixed 3' read A
AI191926.1 Clone IMAGE:1734125 testis 3' read A
AI268494.1 Clone IMAGE:1910679 lung 3' read
CB125209.1 Clone L5HLK1s1-12-E12 liver 5' read P
CB113044.1 Clone L6ChoCK0-8-F05 liver 5' read P
CB142242.1 Clone L11SNU354s1-21-A01 liver 5' read P
AI332821.1 Clone IMAGE:1930884 lung 3' read A
AI392667.1 Clone IMAGE:2111893 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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