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UGID:1087262     UniGene Hs.527061     Homo sapiens (human)   RGS12
Regulator of G-protein signaling 12 (RGS12)

Human protein-coding gene RGS12. Represented by 317 ESTs from 153 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 1087262 - Hs.527061]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_937872.1 RGS12 gene product H. sapiens 100.0 1446
XP_003310274.1 PREDICTED: regulator of G-protein signaling 12 isoform 1 P. troglodytes 99.7 1446
NP_775578.2 Rgs12 gene product M. musculus 91.4 1380
NP_001089606.1 regulator of G-protein signaling 12 X. laevis 77.2 722
NP_999889.1 rgs12b gene product D. rerio 71.3 1366
Other hits (2 of 23) [Show all]SpeciesId(%)Len(aa)
XP_003890911.1 PREDICTED: regulator of G-protein signaling 12 P. anubis 98.8 1375
XP_002802183.1 PREDICTED: regulator of G-protein signaling 12-like M. mulatta 97.5 1426

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; eye; uterus; kidney; mixed; skin; embryonic tissue; uncharacterized tissue; intestine; thymus; testis; liver; prostate; pancreas; mammary gland; muscle; lymph node; heart; thyroid; trachea; ovary; placenta; stomach; cervix; mouth; bone; connective tissue; parathyroid; bone marrow; nerve; spleen; esophagus
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4p16.3
UniSTS entry: Chr 4 SHGC-67292
UniSTS entry: Chr 4 WI-11720 [Map Viewer]
UniSTS entry: Chr 4 WI-15158 [Map Viewer]
UniSTS entry: Chr 1 D1S1425
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (22)

AF035152.1 Homo sapiens regulator of G-protein signalling 12 (RGS12) mRNA, complete cds P
AK123325.1 Homo sapiens cDNA FLJ41331 fis, clone BRAMY2047751, highly similar to REGULATOR OF G-PROTEIN SIGNALING 12 P
NM_002926.3 Homo sapiens regulator of G-protein signaling 12 (RGS12), transcript variant 2, mRNA P
NM_198229.2 Homo sapiens regulator of G-protein signaling 12 (RGS12), transcript variant 1, mRNA PA
NM_198227.1 Homo sapiens regulator of G-protein signaling 12 (RGS12), transcript variant 3, mRNA PA
AY987042.1 Homo sapiens regulator of G-protein signalling 12 (RGS12) mRNA, complete cds P
BC106944.1 Homo sapiens regulator of G-protein signaling 12, mRNA (cDNA clone IMAGE:40034300), partial cds P
BC118594.1 Homo sapiens regulator of G-protein signaling 12, mRNA (cDNA clone IMAGE:40108061), complete cds P
AF464737.1 Homo sapiens RGS12TS-S isoform mRNA, complete cds; alternatively spliced P
AF464736.1 Homo sapiens RGS12TS isoform 2 mRNA, complete cds; alternatively spliced P
AF464735.1 Homo sapiens RGS12TS isoform mRNA, complete cds; alternatively spliced P
AK290805.1 Homo sapiens cDNA FLJ78706 complete cds P
AK308734.1 Homo sapiens cDNA, FLJ98775 P
AK310999.1 Homo sapiens cDNA, FLJ18041 P
BC028154.1 Homo sapiens regulator of G-protein signaling 12, mRNA (cDNA clone IMAGE:5241691), partial cds P
BC012118.1 Homo sapiens regulator of G-protein signalling 12, mRNA (cDNA clone IMAGE:4552981), with apparent retained intron PA
AK303135.1 Homo sapiens cDNA FLJ56272 complete cds, highly similar to Regulator of G-protein signaling 12 P
AK301510.1 Homo sapiens cDNA FLJ61433 complete cds, highly similar to Regulator of G-protein signaling 12 P
AK293767.1 Homo sapiens cDNA FLJ61217 complete cds, highly similar to Regulator of G-protein signaling 12 P
AF030110.1 Homo sapiens regulator of G protein signaling RGS12 (RGS) mRNA, complete cds PA
AF030111.1 Homo sapiens regulator of G protein signaling RGS12 (RGS) mRNA, complete cds PA
AF030109.1 Homo sapiens regulator of G protein signaling 12 (RGS12) mRNA, complete cds PA

EST sequences (10 of 317) [Show all sequences]

AA974676.1 Clone IMAGE:1578232 mixed 3' read A
AA985462.1 Clone IMAGE:1594182 kidney 3' read
AA887434.1 Clone IMAGE:1501729 kidney 3' read A
AA910323.1 Clone IMAGE:1520552 kidney 3' read
AA921929.1 Clone IMAGE:1543900 mixed 3' read P
AI079460.1 Clone IMAGE:1677742 mixed 3' read P
AI089751.1 Clone IMAGE:1687251 brain 3' read PA
AI089936.1 Clone IMAGE:1687326 brain 3' read P
AI094724.1 Clone IMAGE:1686169 brain 3' read P
AI094954.1 Clone IMAGE:1686279 brain 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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