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UGID:916369     UniGene Hs.525622     Homo sapiens (human)   AKT1
V-akt murine thymoma viral oncogene homolog 1 (AKT1)

Human protein-coding gene AKT1. Represented by 1025 ESTs from 313 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 916369 - Hs.525622]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001085265.2 PREDICTED: RAC-alpha serine/threonine-protein kinase isoform 2 M. mulatta 100.0 479
XP_003902382.1 PREDICTED: RAC-alpha serine/threonine-protein kinase P. anubis 100.0 479
NP_005154.2 AKT1 gene product H. sapiens 100.0 479
NP_033782.1 Akt1 gene product M. musculus 99.6 479
NP_150233.1 Akt1 gene product R. norvegicus 99.6 479
NP_001083878.1 RAC-alpha serine/threonine-protein kinase X. laevis 97.5 480
NP_001184130.1 akt3a gene product D. rerio 89.6 478
NP_732114.1 Akt1, isoform A D. melanogaster 71.8 511
NP_001023646.1 Protein AKT-1, isoform b C. elegans 67.0 536
XP_962134.2 serine/threonine-protein kinase gad8 N. crassa 52.7 353
NP_012755.1 Tpk3p S. cerevisiae 49.8 273
XP_001693559.1 ribosomal protein S6 kinase C. reinhardtii 49.0 196
NP_187485.1 serine/threonine-protein kinase AtPK1/AtPK6 A. thaliana 47.0 181
Other hits (2 of 64) [Show all]SpeciesId(%)Len(aa)
XP_548000.3 PREDICTED: RAC-alpha serine/threonine-protein kinase C. lupus familiaris 99.0 479
NP_001153248.1 AKT1 gene product S. scrofa 99.0 479

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; prostate; lung; skin; pancreas; liver; mammary gland; eye; uterus; embryonic tissue; placenta; intestine; ovary; lymph; salivary gland; heart; kidney; mixed; connective tissue; ascites; adrenal gland; muscle; uncharacterized tissue; lymph node; testis; cervix; blood; thyroid; larynx; stomach; tonsil; bone; thymus; mouth; bone marrow; bladder; adipose tissue; amniotic fluid; vascular; spleen; nerve; trachea; umbilical cord; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 14
Map position: 14q32.32
UniSTS entry: Chr 14 RH101916
UniSTS entry: Chr 14 RH47592
UniSTS entry: Chr 14 STS-AA041305 [Map Viewer]
UniSTS entry: Chr 14 RH69160
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

M63167.1 Human rac protein kinase alpha mRNA, complete cds P
BX648205.1 Homo sapiens mRNA; cDNA DKFZp686K13249 (from clone DKFZp686K13249) PA
AK122894.1 Homo sapiens cDNA FLJ16549 fis, clone PLACE7003657, highly similar to RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) P
NM_005163.2 Homo sapiens v-akt murine thymoma viral oncogene homolog 1 (AKT1), transcript variant 1, mRNA PA
BC063408.1 Homo sapiens v-akt murine thymoma viral oncogene homolog 1, mRNA (cDNA clone IMAGE:5212292) A
BC084538.1 Homo sapiens v-akt murine thymoma viral oncogene homolog 1, mRNA (cDNA clone MGC:99656 IMAGE:6645486), complete cds PA
NM_001014432.1 Homo sapiens v-akt murine thymoma viral oncogene homolog 1 (AKT1), transcript variant 2, mRNA PA
NM_001014431.1 Homo sapiens v-akt murine thymoma viral oncogene homolog 1 (AKT1), transcript variant 3, mRNA PA
BC001737.1 Homo sapiens, clone IMAGE:3354010, mRNA, partial cds PA
BC000479.2 Homo sapiens v-akt murine thymoma viral oncogene homolog 1, mRNA (cDNA clone MGC:8686 IMAGE:2964603), complete cds PA
AK314256.1 Homo sapiens cDNA, FLJ95003, Homo sapiens v-akt murine thymoma viral oncogene homolog 1 (AKT1),mRNA P
AB451367.1 Homo sapiens AKT1 mRNA for v-akt murine thymoma viral oncogene homolog 1, partial cds, clone: FLJ08041AAAF P
AB451242.1 Homo sapiens AKT1 mRNA for v-akt murine thymoma viral oncogene homolog 1, complete cds, clone: FLJ08041AAAN P
AK299310.1 Homo sapiens cDNA FLJ53606 complete cds, highly similar to RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) P
X61037.1 H.sapiens mRNA for protein kinase B P

EST sequences (10 of 1025) [Show all sequences]

AA962189.1 Clone IMAGE:1591650 kidney 3' read
AA910628.1 Clone IMAGE:1518437 uncharacterized tissue 3' read A
AA926953.1 Clone IMAGE:1552371 uncharacterized tissue 3' read
R20913.1 Clone IMAGE:130110 placenta 5' read
AI079186.1 Clone IMAGE:1669805 brain 3' read P
AI089552.1 Clone IMAGE:1695493 uterus 3' read A
AI092106.1 Clone IMAGE:1690994 mixed 3' read P
AA910085.1 Clone IMAGE:1525983 mixed 3' read P
AI131552.1 Clone IMAGE:1706600 heart 3' read A
AI140219.1 Clone IMAGE:1739560 lung 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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