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UGID:914215     UniGene Hs.523468     Homo sapiens (human)   SCUBE2
Signal peptide, CUB domain, EGF-like 2 (SCUBE2)

Human protein-coding gene SCUBE2. Represented by 154 ESTs from 66 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 914215 - Hs.523468]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_066025.2 SCUBE2 gene product H. sapiens 100.0 970
NP_064436.2 signal peptide, CUB and EGF-like domain-containing protein 2 precursor M. musculus 93.1 967
NP_001014813.1 scube2 gene product D. rerio 75.3 1008
NP_001255803.1 Protein Y64G10A.7, isoform a C. elegans 46.7 165
Other hits (2 of 32) [Show all]SpeciesId(%)Len(aa)
XP_001168946.1 PREDICTED: signal peptide, CUB domain, EGF-like 2 isoform 1 P. troglodytes 99.5 968
XP_003910295.1 PREDICTED: signal peptide, CUB and EGF-like domain-containing protein 2 isoform 2 P. anubis 98.1 967

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mammary gland; prostate; mixed; brain; heart; intestine; pancreas; placenta; uncharacterized tissue; testis; kidney; ovary; eye; lung; stomach; ganglia; pharynx; connective tissue; embryonic tissue; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11p15.3
UniSTS entry: Chr 11 RH71184 [Map Viewer]
UniSTS entry: Chr 11 G59675
UniSTS entry: Chr 11 RH45205 [Map Viewer]
UniSTS entry: Chr 11 MARC_14461-14462:1010436954:1
UniSTS entry: Chr 1 D11S2921
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

AK126806.1 Homo sapiens cDNA FLJ44856 fis, clone BRACE3052569
AK123039.1 Homo sapiens cDNA FLJ41044 fis, clone NT2RP7000466, highly similar to Mus musculus CUB domain and EGF-like repeat containing 1 (Cegf1) P
BC111690.1 Homo sapiens signal peptide, CUB domain, EGF-like 2, mRNA (cDNA clone MGC:133057 IMAGE:40008764), complete cds P
NM_020974.2 Homo sapiens signal peptide, CUB domain, EGF-like 2 (SCUBE2), transcript variant 1, mRNA P
AK092153.1 Homo sapiens cDNA FLJ34834 fis, clone NT2NE2010105 P
AF086390.1 Homo sapiens full length insert cDNA clone ZD73H01 A
NM_001170690.1 Homo sapiens signal peptide, CUB domain, EGF-like 2 (SCUBE2), transcript variant 2, mRNA P

EST sequences (10 of 154) [Show all sequences]

AI000160.1 Clone IMAGE:1608214 mammary gland 3' read
AI128582.1 Clone IMAGE:1691237 heart 3' read
AI146289.1 Clone IMAGE:1707084 heart 3' read P
CB050246.1 Clone IMAGE:3271942 prostate 3' read A
CB050247.1 Clone IMAGE:3271942 prostate 5' read
BX114287.1 Clone IMAGp998J064294_;_IMAGE:1691237 heart
BX090430.1 Clone IMAGp998D02792_;_IMAGE:346321 heart A
AI276664.1 Clone IMAGE:1877595 mixed 3' read A
BM422377.1 testis PA
AI247191.1 Clone IMAGE:1998765 stomach 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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