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UGID:914049     UniGene Hs.523302     Homo sapiens (human)   PRDX3
Peroxiredoxin 3 (PRDX3)

Human protein-coding gene PRDX3. Represented by 1936 ESTs from 342 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 914049 - Hs.523302]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003951819.1 PREDICTED: thioredoxin-dependent peroxide reductase, mitochondrial P. troglodytes 100.0 255
NP_006784.1 PRDX3 gene product H. sapiens 100.0 255
NP_031478.1 Prdx3 gene product M. musculus 94.5 256
NP_001089616.1 uncharacterized protein LOC734674 X. laevis 90.0 250
NP_001013478.2 prdx3 gene product D. rerio 84.0 249
NP_477510.1 thioredoxin peroxidase 1, isoform A D. melanogaster 69.6 193
NP_497892.1 Protein PRDX-3 C. elegans 67.7 216
XP_001699660.1 2-cys peroxiredoxin C. reinhardtii 67.7 197
NP_013684.1 Tsa1p S. cerevisiae 62.8 195
NP_568166.1 2-Cys peroxiredoxin BAS1-like protein A. thaliana 60.3 256
Other hits (2 of 62) [Show all]SpeciesId(%)Len(aa)
XP_001097456.1 PREDICTED: thioredoxin-dependent peroxide reductase, mitochondrial isoform 3 M. mulatta 99.2 255
XP_003904375.1 PREDICTED: thioredoxin-dependent peroxide reductase, mitochondrial P. anubis 99.2 255

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; kidney; bone marrow; liver; lung; uncharacterized tissue; bladder; blood; placenta; embryonic tissue; prostate; mixed; skin; muscle; intestine; uterus; pancreas; pharynx; salivary gland; eye; adrenal gland; thymus; cervix; heart; adipose tissue; ovary; vascular; thyroid; spleen; umbilical cord; ascites; mammary gland; stomach; bone; lymph node; pituitary gland; connective tissue; parathyroid; ear; lymph; mouth; epididymis; amniotic fluid; nerve; ganglia; tonsil; trachea
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q25-q26
UniSTS entry: Chr 10 PRDX3-1
UniSTS entry: Chr 10 RH71324 [Map Viewer]
UniSTS entry: Chr 10 RH11191
UniSTS entry: Chr 10 RH68895
UniSTS entry: Chr 10 G43270
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

NM_014098.2 Homo sapiens peroxiredoxin 3 (PRDX3), nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA P
AK130897.1 Homo sapiens cDNA FLJ27387 fis, clone UBA09535, highly similar to Mitochondrial thioredoxin-dependent peroxide reductase precursor P
NM_006793.2 Homo sapiens peroxiredoxin 3 (PRDX3), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA P
BC059169.1 Homo sapiens peroxiredoxin 3, mRNA (cDNA clone MGC:14578 IMAGE:4133576), complete cds PA
CR450344.1 Homo sapiens full open reading frame cDNA clone RZPDo834F012D for gene PRDX3, peroxiredoxin 3; complete cds; without stopcodon P
BT020007.1 Homo sapiens peroxiredoxin 3 mRNA, complete cds P
AK222659.1 Homo sapiens mRNA for peroxiredoxin 3 isoform a precursor variant, clone: CBL07612 P
BC002685.1 Homo sapiens peroxiredoxin 3, mRNA (cDNA clone MGC:3522 IMAGE:3607558), complete cds PA
BC111397.1 Homo sapiens peroxiredoxin 3, mRNA (cDNA clone MGC:104387 IMAGE:4246143), complete cds PA
D49396.1 Homo sapiens Aop1 mRNA for antioxidant protein 1, complete cds PA
BC007062.1 Homo sapiens peroxiredoxin 3, mRNA (cDNA clone MGC:12511 IMAGE:3960644), complete cds PA
BC008435.1 Homo sapiens peroxiredoxin 3, mRNA (cDNA clone MGC:14634 IMAGE:4081846), complete cds PA
EF036492.1 Homo sapiens peroxiredoxin 3 isoform a precursor, mRNA, partial cds P
BC009601.1 Homo sapiens peroxiredoxin 3, mRNA (cDNA clone MGC:14693 IMAGE:4134666), complete cds PA
BC022373.1 Homo sapiens peroxiredoxin 3, mRNA (cDNA clone MGC:23923 IMAGE:4775243), complete cds PA
BC021691.1 Homo sapiens peroxiredoxin 3, mRNA (cDNA clone MGC:24293 IMAGE:3961379), complete cds PA
AK313169.1 Homo sapiens cDNA, FLJ93665, Homo sapiens peroxiredoxin 3 (PRDX3), nuclear gene encoding mitochondrial protein, mRNA P
X85129.1 H.sapiens mRNA for humer

EST sequences (10 of 1936) [Show all sequences]

AA962481.1 Clone IMAGE:1573583 kidney 3' read A
AA905622.1 Clone IMAGE:1506028 mixed 3' read A
AA969819.1 Clone IMAGE:1572738 kidney 3' read A
AA988963.1 Clone IMAGE:1602829 lung 3' read A
R17871.1 Clone IMAGE:31998 brain 5' read P
AI024304.1 Clone IMAGE:1642410 testis 3' read A
R18749.1 Clone IMAGE:32727 brain 5' read P
AI027088.1 Clone IMAGE:1649751 parathyroid 3' read
R20906.1 Clone IMAGE:130089 placenta 5' read
AI078238.1 Clone IMAGE:1675930 mixed 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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