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UGID:912400     UniGene Hs.521653     Homo sapiens (human)   MUSK
Muscle, skeletal, receptor tyrosine kinase (MUSK)

Human protein-coding gene MUSK. Represented by 17 ESTs from 12 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 912400 - Hs.521653]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_005583.1 MUSK gene product H. sapiens 100.0 868
XP_001146498.1 PREDICTED: muscle, skeletal receptor tyrosine-protein kinase isoform 6 P. troglodytes 99.8 868
NP_035074.2 Musk gene product M. musculus 94.3 867
NP_001004503.1 musk gene product D. rerio 68.0 926
NP_477255.1 neurospecific receptor kinase D. melanogaster 59.2 292
NP_001079579.1 neurotrophic tyrosine kinase, receptor, type 2 X. laevis 48.9 276
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_001106626.1 PREDICTED: muscle, skeletal receptor tyrosine-protein kinase-like isoform 4 M. mulatta 99.3 868
XP_003911428.1 PREDICTED: muscle, skeletal receptor tyrosine-protein kinase-like, partial P. anubis 99.1 460

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; mouth; brain; testis; lung; mixed; connective tissue; muscle; embryonic tissue; eye
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9q31.3-q32
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_005592.3 Homo sapiens muscle, skeletal, receptor tyrosine kinase (MUSK), transcript variant 1, mRNA P
BC109099.1 Homo sapiens muscle, skeletal, receptor tyrosine kinase, mRNA (cDNA clone MGC:126324 IMAGE:40034773), complete cds P
BC109098.1 Homo sapiens muscle, skeletal, receptor tyrosine kinase, mRNA (cDNA clone MGC:126323 IMAGE:40034772), complete cds P
Z25436.1 H.sapiens protein-tyrosine kinase gene, complete CDS
NM_001166281.1 Homo sapiens muscle, skeletal, receptor tyrosine kinase (MUSK), transcript variant 3, mRNA P
NM_001166280.1 Homo sapiens muscle, skeletal, receptor tyrosine kinase (MUSK), transcript variant 2, mRNA P
AF006464.1 Homo sapiens muscle specific tyrosine kinase receptor (MUSK) mRNA, complete cds P

EST sequences (10 of 17) [Show all sequences]

BX106537.1 Clone IMAGp998J214941_;_IMAGE:2009204 uncharacterized tissue P
AI302067.1 Clone IMAGE:1898705 lung 3' read P
AI341122.1 Clone IMAGE:2009204 uncharacterized tissue 3' read P
AI341265.1 Clone IMAGE:2009276 uncharacterized tissue 3' read P
AI800924.1 Clone IMAGE:2365089 mixed 3' read P
AW378446.1 mouth
BE146709.1 mouth
BE146719.1 mouth
DA182433.1 Clone BRAMY2047654 brain 5' read P
DA334836.1 Clone BRHIP3034445 brain 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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