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UGID:912203     UniGene Hs.521456     Homo sapiens (human)   TNFRSF10B
Tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B)

Human protein-coding gene TNFRSF10B. Represented by 561 ESTs from 184 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 912203 - Hs.521456]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003833.4 TNFRSF10B gene product H. sapiens 100.0 439
Other hits (2 of 6) [Show all]SpeciesId(%)Len(aa)
XP_001158074.1 PREDICTED: tumor necrosis factor receptor superfamily member 10B isoform 2 P. troglodytes 98.5 409
XP_003902583.1 PREDICTED: tumor necrosis factor receptor superfamily member 10B P. anubis 86.3 416

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: intestine; testis; embryonic tissue; brain; prostate; uterus; lung; kidney; mouth; placenta; adrenal gland; pharynx; amniotic fluid; uncharacterized tissue; pancreas; eye; mixed; lymph node; muscle; ovary; trachea; liver; vascular; stomach; thyroid; skin; connective tissue; thymus; cervix; spleen; mammary gland; blood; larynx; ascites; lymph; umbilical cord; bone marrow; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8p22-p21
UniSTS entry: Chr 8 D8S2055 [Map Viewer]
UniSTS entry: Chr 8 WI-15306 [Map Viewer]
UniSTS entry: Chr 1 D11S2560
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Chr 1 D11S3114
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (25)

BX538179.1 Homo sapiens mRNA; cDNA DKFZp686B23188 (from clone DKFZp686B23188) PA
BX537617.1 Homo sapiens mRNA; cDNA DKFZp686A24188 (from clone DKFZp686A24188) PA
AY358277.1 Homo sapiens clone DNA27868 TNFRSF10B/DR5 (UNQ160) mRNA, complete cds P
NM_003842.4 Homo sapiens tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1, mRNA PA
CR541898.1 Homo sapiens full open reading frame cDNA clone RZPDo834D1033D for gene TNFRSF10B, tumor necrosis factor receptor superfamily, member 10b; complete cds, incl. stopcodon P
AF192548.1 Homo sapiens tumor necrosis factor receptor-like protein ZTNFR9 (ZTNFR9) mRNA, complete cds P
AF153687.1 Homo sapiens Fas-like protein precusor mRNA, complete cds PA
BC001281.1 Homo sapiens tumor necrosis factor receptor superfamily, member 10b, mRNA (cDNA clone MGC:5144 IMAGE:3458466), complete cds PA
AK291216.1 Homo sapiens cDNA FLJ76289 complete cds, highly similar to Homo sapiens tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1, mRNA P
AB451399.1 Homo sapiens TNFRSF10B mRNA for tumor necrosis factor receptor superfamily member 10B precursor, partial cds, clone: FLJ08099AAAF P
AB451272.1 Homo sapiens TNFRSF10B mRNA for tumor necrosis factor receptor superfamily member 10B precursor, complete cds, clone: FLJ08099AAAN P
NM_147187.2 Homo sapiens tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 2, mRNA PA
AK298602.1 Homo sapiens cDNA FLJ52718 complete cds, highly similar to Homo sapiens tumor necrosis factor receptor superfamily, member 10b, transcript variant 2, mRNA P
AK296128.1 Homo sapiens cDNA FLJ59908 complete cds, highly similar to Tumor necrosis factor receptor superfamily member 10B precursor P
NR_027140.1 Homo sapiens tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 3, non-coding RNA PA
FJ200482.1 Homo sapiens TNF receptor superfamily member 10b variant mRNA, complete cds
AF012535.1 Homo sapiens death receptor 5 (DR5) mRNA, complete cds P
AF012628.1 Homo sapiens death domain containing receptor for TRAIL/Apo-2L (DR5) mRNA, complete cds P
AF018657.1 Homo sapiens apoptosis inducing protein (TRICK2A) mRNA, complete cds P
AF018658.1 Homo sapiens apoptosis inducing protein (TRICK2B) mRNA, complete cds P
AF020501.1 Homo sapiens cytotoxic TRAIL receptor-2 (DR5) mRNA, complete cds P
AF022386.1 Homo sapiens p53-regulated DNA damage-inducible cell death receptor (killer) mRNA, complete cds P
AF016849.1 Homo sapiens apoptosis inducing receptor TRAIL-R2 (TRAILR2) mRNA, complete cds P
AF016266.1 Homo sapiens TRAIL receptor 2 mRNA, complete cds PA
AF016268.1 Homo sapiens death receptor 5 (DR5) mRNA, complete cds PA

EST sequences (10 of 561) [Show all sequences]

AI038180.1 Clone IMAGE:1660069 embryonic tissue 3' read
AI150453.1 Clone IMAGE:1752557 testis 3' read
AI086562.1 Clone IMAGE:1680879 skin 3' read P
AI250658.1 Clone IMAGE:2004416 pancreas 3' read A
CB154752.1 Clone B2N807043-24-C12 brain 5' read
CB127266.1 Clone C1SNU17-3-E08 cervix 5' read
CB130239.1 Clone L11SNU354-21-E02 liver 5' read P
CB145628.1 Clone L11SNU354s1-13-F06 liver 5' read P
AI420416.1 Clone IMAGE:2095486 prostate 3' read A
AI453143.1 Clone IMAGE:2143484 pancreas 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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