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UGID:910379     UniGene Hs.519632     Homo sapiens (human)   HDAC3
Histone deacetylase 3 (HDAC3)

Human protein-coding gene HDAC3. Represented by 354 ESTs from 180 cDNA libraries. Corresponds to reference sequence NM_003883.3. [UniGene 910379 - Hs.519632]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_034541.2 Hdac3 gene product M. musculus 100.0 427
NP_445900.1 Hdac3 gene product R. norvegicus 100.0 427
XP_001094295.1 PREDICTED: histone deacetylase 3-like isoform 3 M. mulatta 100.0 427
XP_003900298.1 PREDICTED: histone deacetylase 3 P. anubis 100.0 427
XP_001151495.1 PREDICTED: histone deacetylase 3 isoform 5 P. troglodytes 100.0 427
NP_003874.2 HDAC3 gene product H. sapiens 100.0 427
XP_535219.2 PREDICTED: histone deacetylase 3 isoform 1 C. lupus familiaris 100.0 427
XP_001504028.1 PREDICTED: histone deacetylase 3-like E. caballus 100.0 427
NP_001230756.1 HDAC3 gene product S. scrofa 100.0 427
NP_001193172.1 histone deacetylase 3 B. taurus 100.0 427
XP_004008950.1 PREDICTED: histone deacetylase 3 O. aries 100.0 427
XP_002710313.1 PREDICTED: histone deacetylase 3-like O. cuniculus 100.0 427
XP_001368824.1 PREDICTED: histone deacetylase 3-like M. domestica 99.8 427
XP_003210016.1 PREDICTED: histone deacetylase 3-like M. gallopavo 99.5 427
NP_957284.1 hdac3 gene product D. rerio 96.3 427
NP_651978.2 histone deacetylase 3 D. melanogaster 80.7 434
NP_001084011.1 histone deacetylase 2 X. laevis 72.7 436
NP_190054.2 histone deacetylase 9 A. thaliana 71.5 418
XP_001695812.1 histone deacetylase C. reinhardtii 70.0 404
NP_014069.1 Rpd3p S. cerevisiae 69.9 414
NP_506599.1 Protein HDA-1 C. elegans 69.4 432
XP_964367.1 histone deacetylase RPD3 N. crassa 69.4 438
Other hits (2 of 51) [Show all]SpeciesId(%)Len(aa)
XP_003219934.1 PREDICTED: histone deacetylase 3-like A. carolinensis 99.1 427
XP_002189056.1 PREDICTED: histone deacetylase 3 T. guttata 99.1 427

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; lung; uncharacterized tissue; embryonic tissue; skin; pancreas; placenta; liver; stomach; mammary gland; testis; ear; blood; thyroid; intestine; ovary; lymph; uterus; eye; kidney; muscle; prostate; cervix; ascites; heart; lymph node; adrenal gland; tonsil; bladder; bone; connective tissue; spleen; parathyroid; nerve; ganglia; adipose tissue; epididymis
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5q31
UniSTS entry: Chr 5 HSC11A022 [Map Viewer]
UniSTS entry: Chr 5 A007C33 [Map Viewer]
UniSTS entry: Chr 5 SGC30748 [Map Viewer]
UniSTS entry: Chr 5 SGC33638 [Map Viewer]
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_003883.3 Homo sapiens histone deacetylase 3 (HDAC3), mRNA PA
AY429538.1 Homo sapiens HDAC3v_2 mRNA sequence; alternatively spliced P
AY429537.1 Homo sapiens HDAC3v_1 mRNA sequence; alternatively spliced
BC000614.1 Homo sapiens histone deacetylase 3, mRNA (cDNA clone MGC:2041 IMAGE:3345755), complete cds PA
U66914.1 Homo sapiens histone deacetylase 3 (HDAC3) mRNA, complete cds PA
AF005482.1 Homo sapiens histone deacetylase-3C mRNA, complete cds P
U75696.1 Human transcription regulator RPD3-2A (hRPD3-2A) mRNA, complete cds PA
U75697.1 Human transcription regulator RPD3-2B mRNA, complete cds P
AF039703.1 Homo sapiens histone deacetylase 3 (HDAC3) mRNA, complete cds PA

EST sequences (10 of 354) [Show all sequences]

AA887531.1 Clone IMAGE:1500544 lung 3' read A
R18769.1 Clone IMAGE:32733 brain 5' read
AI032111.1 Clone IMAGE:1611246 uncharacterized tissue 3' read A
AI032140.1 Clone IMAGE:1611273 uncharacterized tissue 3' read A
AI034260.1 Clone IMAGE:1646928 parathyroid 3' read
AI074678.1 Clone IMAGE:1662902 mixed 3' read A
R21136.1 Clone IMAGE:36517 brain 5' read P
AA862566.1 Clone IMAGE:1469473 uncharacterized tissue 3' read A
AI187018.1 Clone IMAGE:1741218 lung 3' read A
AI208085.1 Clone IMAGE:1838724 testis 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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