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UGID:908264     UniGene Hs.517517     Homo sapiens (human)   EP300
E1A binding protein p300 (EP300)

Human protein-coding gene EP300. Represented by 357 ESTs from 208 cDNA libraries. Corresponds to reference sequence NM_001429.3. [UniGene 908264 - Hs.517517]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001420.2 EP300 gene product H. sapiens 100.0 2413
NP_001231599.1 histone acetyltransferase p300 P. troglodytes 100.0 2410
XP_003905646.1 PREDICTED: LOW QUALITY PROTEIN: histone acetyltransferase p300 P. anubis 99.7 2415
XP_001102844.1 PREDICTED: histone acetyltransferase p300 M. mulatta 99.7 2413
NP_808489.4 Ep300 gene product M. musculus 96.4 2411
XP_001332718.3 PREDICTED: CREB-binding protein D. rerio 72.7 2641
NP_001088637.1 CREB binding protein X. laevis 71.8 2417
NP_524642.2 nejire, isoform B D. melanogaster 64.6 1413
NP_001122711.2 Protein CBP-1, isoform c C. elegans 57.6 838
NP_001185015.1 histone acetyltransferase HAC12 A. thaliana 52.1 209
Other hits (2 of 43) [Show all]SpeciesId(%)Len(aa)
XP_001502391.1 PREDICTED: histone acetyltransferase p300 E. caballus 98.0 2419
XP_003431544.1 PREDICTED: LOW QUALITY PROTEIN: histone acetyltransferase p300 C. lupus familiaris 97.8 2427

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; embryonic tissue; placenta; blood; intestine; mixed; lymph node; pharynx; thymus; uterus; lung; mammary gland; uncharacterized tissue; muscle; stomach; larynx; prostate; pancreas; testis; liver; thyroid; skin; eye; kidney; connective tissue; esophagus; nerve; spleen; mouth; epididymis; bone; heart; parathyroid; cervix; amniotic fluid; ascites; lymph; bladder; ovary; ganglia; adrenal gland
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 22
Map position: 22q13.2
UniSTS entry: Chr 22 STS-N57495 [Map Viewer]
UniSTS entry: Chr 22 D22S1541
UniSTS entry: Chr 22 RH136048
UniSTS entry: Chr 22 PMC113761P2
UniSTS entry: Chr 22 SGC38348 [Map Viewer]
UniSTS entry: STS-U01877
UniSTS entry: Chr 22 EP300_8165
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (4)

BC053889.1 Homo sapiens E1A binding protein p300, mRNA (cDNA clone IMAGE:6151364), partial cds PA
AK125679.1 Homo sapiens cDNA FLJ43691 fis, clone TBAES2004939
NM_001429.3 Homo sapiens E1A binding protein p300 (EP300), mRNA PA
U01877.1 Human p300 protein mRNA, complete cds P

EST sequences (10 of 357) [Show all sequences]

AA991897.1 Clone IMAGE:1611223 uncharacterized tissue 3' read
AA902750.1 Clone IMAGE:1519122 uncharacterized tissue 3' read
AI033162.1 Clone IMAGE:1654464 mixed 3' read
AA948205.1 Clone IMAGE:1585029 lung 3' read A
AI079333.1 Clone IMAGE:1677471 mixed 3' read
T06350.1 Clone HFBDS28 brain
AI141752.1 Clone IMAGE:1615411 uncharacterized tissue 3' read A
AI148258.1 Clone IMAGE:1680564 skin 3' read A
BX098158.1 Clone IMAGp998I02536_;_IMAGE:248137 mixed
AI189248.1 Clone IMAGE:1722386 uterus 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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