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UGID:906179     UniGene Hs.515432     Homo sapiens (human)   DEDD2
Death effector domain containing 2 (DEDD2)

Human protein-coding gene DEDD2. Represented by 214 ESTs from 127 cDNA libraries. Corresponds to 10 reference sequences (different isoforms). [UniGene 906179 - Hs.515432]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003915662.1 PREDICTED: DNA-binding death effector domain-containing protein 2 isoform 1 P. anubis 100.0 325
NP_579874.1 DEDD2 gene product H. sapiens 100.0 325
NP_997560.3 DNA-binding death effector domain-containing protein 2 M. musculus 97.0 329
NP_001088715.1 death effector domain containing 2 X. laevis 55.5 337
NP_571677.1 dedd1 gene product D. rerio 53.2 342
Other hits (2 of 20) [Show all]SpeciesId(%)Len(aa)
XP_003953554.1 PREDICTED: DNA-binding death effector domain-containing protein 2 P. troglodytes 99.4 325
XP_003127226.2 PREDICTED: DNA-binding death effector domain-containing protein 2-like S. scrofa 97.9 326

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; brain; liver; testis; prostate; kidney; lung; thymus; embryonic tissue; placenta; uterus; mixed; bone marrow; blood; intestine; pancreas; ovary; muscle; eye; heart; tonsil; skin; mammary gland; cervix; stomach; parathyroid; salivary gland; bone; adrenal gland; pineal gland; lymph node; spleen
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19q13.2
UniSTS entry: Chr 19 G31114
UniSTS entry: Chr 19 A005M44
UniSTS entry: Chr 6 SGC34451 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

AK130203.1 Homo sapiens cDNA FLJ26693 fis, clone MPG07953 P
BC013372.2 Homo sapiens death effector domain containing 2, mRNA (cDNA clone MGC:16414 IMAGE:3941907), complete cds PA
AF443591.1 Homo sapiens death effector domain-containing DNA-binding protein 2 (DEDD2) mRNA, complete cds P
AK307895.1 Homo sapiens cDNA, FLJ97843 P
NM_133328.3 Homo sapiens death effector domain containing 2 (DEDD2), transcript variant 1, mRNA PA
AF457575.1 Homo sapiens death effector domain-containing protein FLAME-3 (FLAME-3) mRNA, complete cds P
BC027930.1 Homo sapiens death effector domain containing 2, mRNA (cDNA clone MGC:35529 IMAGE:5199772), complete cds PA
AK075328.1 Homo sapiens cDNA PSEC0004 fis, clone NT2RM1000558, moderately similar to Death effector domain-containing DNA binding protein 2 P
AY125488.1 Homo sapiens death effector domain-containing DNA-binding 2 protein (DEDD2) mRNA, complete cds PA
NR_073051.1 Homo sapiens death effector domain containing 2 (DEDD2), transcript variant 9, non-coding RNA PA
NR_073048.1 Homo sapiens death effector domain containing 2 (DEDD2), transcript variant 6, non-coding RNA PA
NR_073046.1 Homo sapiens death effector domain containing 2 (DEDD2), transcript variant 4, non-coding RNA PA
NM_001270615.1 Homo sapiens death effector domain containing 2 (DEDD2), transcript variant 3, mRNA PA
NR_073052.1 Homo sapiens death effector domain containing 2 (DEDD2), transcript variant 10, non-coding RNA PA
NR_073050.1 Homo sapiens death effector domain containing 2 (DEDD2), transcript variant 8, non-coding RNA PA
NR_073049.1 Homo sapiens death effector domain containing 2 (DEDD2), transcript variant 7, non-coding RNA PA
NR_073047.1 Homo sapiens death effector domain containing 2 (DEDD2), transcript variant 5, non-coding RNA PA
NM_001270614.1 Homo sapiens death effector domain containing 2 (DEDD2), transcript variant 2, mRNA PA

EST sequences (10 of 214) [Show all sequences]

AA908655.1 Clone IMAGE:1522457 lung 3' read A
AI031817.1 Clone IMAGE:1645959 parathyroid 3' read
AI033528.1 Clone IMAGE:1655792 mixed 3' read A
AI090434.1 Clone IMAGE:1672360 uncharacterized tissue 3' read A
AA862542.1 Clone IMAGE:1469460 uncharacterized tissue 3' read A
BX117301.1 Clone IMAGp998F234890_;_IMAGE:1989526 uterus A
AI343327.1 Clone IMAGE:2062038 intestine 3' read A
AI358311.1 Clone IMAGE:1989526 uterus 3' read
AI359207.1 Clone IMAGE:2013168 brain 3' read A
AI360743.1 Clone IMAGE:2011150 brain 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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