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UGID:906164     UniGene Hs.515417     Homo sapiens (human)   EGLN2
Egl nine homolog 2 (C. elegans) (EGLN2)

Human protein-coding gene EGLN2. Represented by 563 ESTs from 232 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 906164 - Hs.515417]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001233442.1 EGLN2 gene product P. troglodytes 100.0 406
NP_542770.2 EGLN2 gene product H. sapiens 100.0 406
XP_001099832.1 PREDICTED: egl nine homolog 2 isoform 5 M. mulatta 99.5 404
XP_003915610.1 PREDICTED: egl nine homolog 2 P. anubis 99.5 404
NP_444438.2 Egln2 gene product M. musculus 94.5 418
NP_998475.1 egln3 gene product D. rerio 71.7 230
NP_001091129.1 uncharacterized protein LOC100036879 X. laevis 71.7 226
NP_730908.1 HIF prolyl hydroxylase, isoform B D. melanogaster 58.7 259
NP_001023833.1 Protein EGL-9, isoform c C. elegans 50.0 158
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
XP_003127193.1 PREDICTED: egl nine homolog 2 S. scrofa 97.8 401
XP_002722361.1 PREDICTED: EGL nine (C.elegans) homolog 2 O. cuniculus 97.3 402

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; cervix; thyroid; pancreas; lung; lymph node; skin; mouth; pharynx; spleen; connective tissue; mixed; placenta; mammary gland; uncharacterized tissue; prostate; embryonic tissue; uterus; intestine; ovary; blood; muscle; adipose tissue; thymus; kidney; heart; eye; stomach; pituitary gland; lymph; trachea; epididymis; bladder; ascites; bone marrow; vascular; bone; adrenal gland; liver; salivary gland; umbilical cord
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19q13.2
UniSTS entry: Chr 19 D2S2863
UniSTS entry: Chr 19 RH93347
UniSTS entry: Chr 19 SHGC-64133
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

BC001723.1 Homo sapiens egl nine homolog 2 (C. elegans), mRNA (cDNA clone IMAGE:3534835), complete cds PA
AJ310544.1 Homo sapiens mRNA for EGLN2 protein PA
NM_053046.3 Homo sapiens egl nine homolog 2 (C. elegans) (EGLN2), transcript variant 1, mRNA PA
NM_080732.3 Homo sapiens egl nine homolog 2 (C. elegans) (EGLN2), transcript variant 3, mRNA PA
AY040565.1 Homo sapiens estrogen-induced tag 6 (EIT6) mRNA, complete cds P
AK074408.1 Homo sapiens cDNA FLJ23828 fis, clone HUV00950, highly similar to Homo sapiens mRNA for EGLN2 protein PA
AK098182.1 Homo sapiens cDNA FLJ40863 fis, clone TRACH2018317, moderately similar to Rattus norvegicus Sprague-Dawley SM-20 mRNA P
AL832506.1 Homo sapiens mRNA; cDNA DKFZp686I0852 (from clone DKFZp686I0852) PA
AK025396.1 Homo sapiens cDNA: FLJ21743 fis, clone COLF4953 A
BC036051.1 Homo sapiens egl nine homolog 2 (C. elegans), mRNA (cDNA clone MGC:33373 IMAGE:5270945), complete cds PA

EST sequences (10 of 563) [Show all sequences]

AA864859.1 Clone IMAGE:1456697 kidney 3' read A
AA973360.1 Clone IMAGE:1568913 lung 3' read A
AA994838.1 Clone IMAGE:1632028 mammary gland 3' read A
AI000652.1 Clone IMAGE:1610103 mammary gland 3' read
AA903776.1 Clone IMAGE:1518918 uncharacterized tissue 3' read A
AI005531.1 Clone IMAGE:1637304 uncharacterized tissue 3' read A
AI017552.1 Clone IMAGE:1628259 mixed 3' read
AI024057.1 Clone IMAGE:1642852 testis 3' read A
AI028027.1 Clone IMAGE:1671455 uncharacterized tissue 3' read P
AI038512.1 Clone IMAGE:1658606 embryonic tissue 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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