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UGID:905909     UniGene Hs.515162     Homo sapiens (human)   CALR
Calreticulin (CALR)

Human protein-coding gene CALR. Represented by 1973 ESTs from 548 cDNA libraries. Corresponds to reference sequence NM_004343.3. [UniGene 905909 - Hs.515162]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001110217.1 PREDICTED: calreticulin isoform 2 M. mulatta 100.0 416
XP_003919471.1 PREDICTED: LOW QUALITY PROTEIN: calreticulin P. anubis 100.0 416
NP_004334.1 CALR gene product H. sapiens 100.0 416
XP_003316194.1 PREDICTED: calreticulin-like P. troglodytes 100.0 413
NP_031617.1 Calr gene product M. musculus 99.8 415
NP_001080096.1 calreticulin precursor X. laevis 88.9 414
NP_956007.1 calrl2 gene product D. rerio 85.1 415
NP_524293.2 calreticulin, isoform A D. melanogaster 81.1 402
NP_504575.1 Protein CRT-1 C. elegans 75.5 390
XP_001689661.1 calreticulin 2, calcium-binding protein C. reinhardtii 64.6 415
NP_172392.1 calreticulin-2 A. thaliana 61.6 423
Other hits (2 of 53) [Show all]SpeciesId(%)Len(aa)
NP_071794.1 Calr gene product R. norvegicus 99.3 415
XP_867310.2 PREDICTED: calreticulin isoform 4 C. lupus familiaris 98.8 416

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lung; brain; embryonic tissue; uterus; mammary gland; uncharacterized tissue; skin; prostate; intestine; testis; eye; kidney; pancreas; placenta; ovary; connective tissue; liver; thyroid; bone; blood; heart; stomach; mixed; ascites; lymph; epididymis; cervix; lymph node; bladder; larynx; muscle; mouth; pharynx; amniotic fluid; esophagus; vascular; pituitary gland; nerve; parathyroid; bone marrow; salivary gland; adrenal gland; ganglia; thymus; spleen
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p13.3-p13.2
UniSTS entry: Chr 19 STS-M84739
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

M32294.1 Human Ro ribonucleoprotein autoantigen (Ro/SS-A), complete cds P
BT007448.1 Homo sapiens calreticulin mRNA, complete cds P
AK130190.1 Homo sapiens cDNA FLJ26680 fis, clone MPG04548, highly similar to Calreticulin precursor P
NM_004343.3 Homo sapiens calreticulin (CALR), mRNA PA
M84739.1 Human autoantigen calreticulin mRNA, complete cds PA
CR457070.1 Homo sapiens full open reading frame cDNA clone RZPDo834G0511D for gene CALR, calreticulin; complete cds, incl. stopcodon P
AK223060.1 Homo sapiens mRNA for calreticulin precursor variant, clone: JTH13773 PA
BC107102.2 Homo sapiens cDNA clone IMAGE:40016136 P
BC002500.2 Homo sapiens calreticulin, mRNA (cDNA clone MGC:2227 IMAGE:3050717), complete cds PA
BC007911.1 Homo sapiens calreticulin, mRNA (cDNA clone MGC:14363 IMAGE:4299303), complete cds PA
AY047586.1 Homo sapiens calreticulin (CALR) mRNA, complete cds P
BC020493.1 Homo sapiens calreticulin, mRNA (cDNA clone MGC:10100 IMAGE:3898550), complete cds PA
AK304492.1 Homo sapiens cDNA FLJ58668 complete cds, highly similar to Calreticulin precursor P
AB451408.1 Homo sapiens CALR mRNA for calreticulin precursor, partial cds, clone: FLJ08113AAAF P
AF087986.1 Homo sapiens full length insert cDNA clone YX19H04 P

EST sequences (10 of 1973) [Show all sequences]

AA961825.1 Clone IMAGE:1600298 uncharacterized tissue 3' read A
AA971568.1 Clone IMAGE:1583515 mixed 3' read A
AA976396.1 Clone IMAGE:1591522 kidney 3' read
AA976974.1 Clone IMAGE:1587522 uncharacterized tissue 3' read PA
AA989306.1 Clone IMAGE:1602409 lung 3' read P
AA992615.1 Clone IMAGE:1618207 testis 3' read A
AA910371.1 Clone IMAGE:1520611 kidney 3' read A
AI028238.1 Clone IMAGE:1645532 testis 3' read A
AI026626.1 Clone IMAGE:1645245 testis 3' read A
AI037886.1 Clone IMAGE:1664703 skin 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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