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UGID:905839     UniGene Hs.515092     Homo sapiens (human)   CLPP
ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli) (CLPP)

Human protein-coding gene CLPP. Represented by 349 ESTs from 164 cDNA libraries. Corresponds to reference sequence NM_006012.2. [UniGene 905839 - Hs.515092]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_512312.2 PREDICTED: putative ATP-dependent Clp protease proteolytic subunit, mitochondrial P. troglodytes 100.0 276
NP_006003.1 CLPP gene product H. sapiens 100.0 276
XP_003914800.1 PREDICTED: putative ATP-dependent Clp protease proteolytic subunit, mitochondrial P. anubis 99.6 276
NP_059089.1 Clpp gene product M. musculus 97.8 271
NP_001018520.1 clpp gene product D. rerio 90.5 253
NP_001088816.1 ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog X. laevis 89.8 243
NP_609388.1 CG5045, isoform A D. melanogaster 76.5 242
NP_001254239.1 Protein CLPP-1, isoform d C. elegans 73.1 212
XP_001697051.1 catalytic subunit of mitochondrial ClpXP protease C. reinhardtii 71.5 207
NP_568427.1 ATP-dependent Clp protease proteolytic subunit 2 A. thaliana 67.8 202
Other hits (2 of 47) [Show all]SpeciesId(%)Len(aa)
XP_003480866.1 PREDICTED: putative ATP-dependent Clp protease proteolytic subunit, mitochondrial-like, partial S. scrofa 98.5 196
NP_001039879.1 CLPP gene product B. taurus 97.8 271

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lung; brain; skin; uncharacterized tissue; uterus; heart; mixed; pituitary gland; blood; eye; mammary gland; stomach; pancreas; lymph; ovary; liver; muscle; prostate; bone; mouth; pineal gland; tonsil; salivary gland; ascites; connective tissue; intestine; lymph node; thymus; embryonic tissue; placenta; kidney; testis; trachea; adrenal gland; vascular; cervix
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p13.3
UniSTS entry: Chr 19 SHGC-31644 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

NM_006012.2 Homo sapiens ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli) (CLPP), nuclear gene encoding mitochondrial protein, mRNA PA
Z50853.1 H.sapiens mRNA for CLPP P
BC002956.1 Homo sapiens ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli), mRNA (cDNA clone MGC:1379 IMAGE:3542292), complete cds PA
EF036491.1 Homo sapiens ClpP caseinolytic peptidase ATP-dependent, proteolytic subunit mRNA, partial cds
AK311973.1 Homo sapiens cDNA, FLJ92246, highly similar to Homo sapiens ClpP caseinolytic protease, ATP-dependent, proteolyticsubunit homolog (E. coli) (CLPP), nuclear gene encodingmitochondrial protein, mRNA P

EST sequences (10 of 349) [Show all sequences]

AA903697.1 Clone IMAGE:1517821 uncharacterized tissue 3' read
AA978258.1 Clone IMAGE:1579862 mixed 3' read P
AA988493.1 Clone IMAGE:1603015 lung 3' read PA
AI016184.1 Clone IMAGE:1622453 embryonic tissue 3' read A
AA927482.1 Clone IMAGE:1542311 mixed 3' read P
AA948541.1 Clone IMAGE:1561805 mixed 3' read
AI081496.1 Clone IMAGE:1679102 skin 3' read A
AI095101.1 Clone IMAGE:1686788 brain 3' read PA
AI097378.1 Clone IMAGE:1698677 uterus 3' read PA
AI086627.1 Clone IMAGE:1681291 skin 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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