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UGID:905800     UniGene Hs.515053     Homo sapiens (human)   AES
Amino-terminal enhancer of split (AES)

Human protein-coding gene AES. Represented by 1180 ESTs from 374 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 905800 - Hs.515053]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_945320.1 AES gene product H. sapiens 100.0 263
NP_034477.1 amino-terminal enhancer of split isoform 1 M. musculus 100.0 196
NP_062093.1 Aes gene product R. norvegicus 100.0 196
XP_001362120.1 PREDICTED: amino-terminal enhancer of split-like M. domestica 100.0 196
NP_001121969.1 AES gene product B. taurus 100.0 196
NP_001083532.1 amino-terminal enhancer of split X. laevis 96.5 196
NP_570986.1 chico gene product D. rerio 94.0 198
NP_001247309.1 groucho, isoform H D. melanogaster 63.3 240
Other hits (2 of 32) [Show all]SpeciesId(%)Len(aa)
XP_003914690.1 PREDICTED: amino-terminal enhancer of split P. anubis 99.4 169
XP_003642896.1 PREDICTED: amino-terminal enhancer of split-like G. gallus 99.4 155

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; eye; uncharacterized tissue; prostate; pancreas; mixed; placenta; skin; uterus; intestine; embryonic tissue; muscle; larynx; thyroid; adrenal gland; tonsil; stomach; mammary gland; blood; kidney; parathyroid; heart; ascites; salivary gland; testis; ovary; lymph node; bone; liver; cervix; connective tissue; nerve; bladder; lymph; esophagus; spleen; thymus; bone marrow; pituitary gland; pharynx; mouth; pineal gland; vascular; ganglia; amniotic fluid; adipose tissue
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p13.3
UniSTS entry: Chr 19 RH69316
UniSTS entry: Chr 19 G32846
UniSTS entry: Chr 19 A009U26
UniSTS entry: Chr 19 AES_7743
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

AF072902.1 Homo sapiens gp130 associated protein GAM mRNA, complete cds P
NM_001130.5 Homo sapiens amino-terminal enhancer of split (AES), transcript variant 2, mRNA PA
NM_198970.1 Homo sapiens amino-terminal enhancer of split (AES), transcript variant 3, mRNA PA
NM_198969.1 Homo sapiens amino-terminal enhancer of split (AES), transcript variant 1, mRNA PA
U04241.1 Human homolog of Drosophila enhancer of split m9/m10 mRNA, complete cds P
BC113737.1 Homo sapiens amino-terminal enhancer of split, mRNA (cDNA clone MGC:142297 IMAGE:8322789), complete cds P
BC113735.1 Homo sapiens amino-terminal enhancer of split, mRNA (cDNA clone MGC:142295 IMAGE:8322787), complete cds P
AF269289.1 Homo sapiens PP2150 mRNA, complete cds PA
AK314713.1 Homo sapiens cDNA, FLJ95570, Homo sapiens amino-terminal enhancer of split (AES), mRNA P
X73358.1 H.sapiens hAES-1 mRNA P
AK095154.1 Homo sapiens cDNA FLJ37835 fis, clone BRSSN2010110, weakly similar to GRG PROTEIN
AK094591.1 Homo sapiens cDNA FLJ37272 fis, clone BRAMY2012091, highly similar to Homo sapiens amino-terminal enhancer of split (AES), transcript variant 1, mRNA P
X73357.1 H.sapiens hAES-2 mRNA P

EST sequences (10 of 1180) [Show all sequences]

AA864774.1 Clone IMAGE:1456638 kidney 3' read
AA970175.1 Clone IMAGE:1581272 mixed 3' read P
AA972771.1 Clone IMAGE:1585110 lung 3' read
R15997.1 Clone IMAGE:53172 brain 3' read
AA991951.1 Clone IMAGE:1613500 uncharacterized tissue 3' read
AA991992.1 Clone IMAGE:1613596 uncharacterized tissue 3' read
AA993588.1 Clone IMAGE:1619665 testis 3' read A
AI000494.1 Clone IMAGE:1613079 uncharacterized tissue 3' read A
AI000576.1 Clone IMAGE:1609157 mammary gland 3' read P
AA911178.1 Clone IMAGE:1520333 kidney 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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