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UGID:902662     UniGene Hs.511915     Homo sapiens (human)   ENO2
Enolase 2 (gamma, neuronal) (ENO2)

Human protein-coding gene ENO2. Represented by 1495 ESTs from 264 cDNA libraries. Corresponds to reference sequence NM_001975.2. [UniGene 902662 - Hs.511915]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001110839.1 PREDICTED: gamma-enolase isoform 1 M. mulatta 100.0 433
XP_003905942.1 PREDICTED: gamma-enolase isoform 1 P. anubis 100.0 433
NP_001966.1 ENO2 gene product H. sapiens 100.0 433
XP_001497628.1 PREDICTED: gamma-enolase E. caballus 99.8 433
XP_004006971.1 PREDICTED: gamma-enolase O. aries 99.8 433
XP_002712960.1 PREDICTED: enolase 2-like O. cuniculus 99.8 433
XP_003639985.1 PREDICTED: gamma-enolase-like isoform 1 C. lupus familiaris 99.5 433
NP_001094595.1 ENO2 gene product B. taurus 99.5 433
NP_038537.1 Eno2 gene product M. musculus 99.3 433
NP_001080346.1 enolase 3 X. laevis 90.0 431
NP_001003848.1 eno2 gene product D. rerio 88.5 433
NP_495900.1 Protein ENOL-1, isoform a C. elegans 78.6 433
NP_477421.1 enolase, isoform A D. melanogaster 77.8 432
NP_181192.1 bifunctional enolase 2/transcriptional activator A. thaliana 76.6 441
XP_001702971.1 enolase C. reinhardtii 74.2 449
NP_011770.3 phosphopyruvate hydratase ENO1 S. cerevisiae 68.2 436
XP_957959.1 enolase N. crassa 67.9 436
Other hits (2 of 60) [Show all]SpeciesId(%)Len(aa)
NP_647541.1 Eno2 gene product R. norvegicus 99.3 433
XP_001925764.3 PREDICTED: gamma-enolase isoform 1 S. scrofa 99.3 433

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; eye; testis; kidney; uncharacterized tissue; lung; adrenal gland; parathyroid; heart; vascular; thyroid; esophagus; spleen; thymus; pancreas; intestine; epididymis; skin; larynx; mixed; ovary; embryonic tissue; mammary gland; cervix; uterus; pituitary gland; liver; lymph; tonsil; connective tissue; nerve; ganglia; pineal gland; blood; muscle; placenta; ear; stomach; mouth; trachea; bone; lymph node; amniotic fluid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12p13
UniSTS entry: Chr 12 G10506
UniSTS entry: Chr 12 D12S1899 [Map Viewer]
UniSTS entry: MARC_4643-4644:966894536:1
UniSTS entry: Chr 12 GDB:384728
UniSTS entry: Chr 12 SHGC-58828
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

Y00691.1 H.spaiens 3' mRNA for neurone-specific enolase (EC 4.2.1.11)
BT007383.1 Homo sapiens enolase 2, (gamma, neuronal) mRNA, complete cds P
AK124656.1 Homo sapiens cDNA FLJ42665 fis, clone BRAMY2019989, highly similar to Gamma-enolase (EC 4.2.1.11) P
NM_001975.2 Homo sapiens enolase 2 (gamma, neuronal) (ENO2), mRNA P
CR536582.1 Homo sapiens full open reading frame cDNA clone RZPDo834F1122D for gene ENO2, enolase 2, (gamma, neuronal); complete cds, incl. stopcodon P
M22349.1 Human neuron-specific gamma-2 enolase, complete cds P
M36768.1 Human gamma enolase mRNA, 3' end P
BC002745.2 Homo sapiens enolase 2 (gamma, neuronal), mRNA (cDNA clone MGC:3520 IMAGE:3629603), complete cds PA
AK290525.1 Homo sapiens cDNA FLJ77877 complete cds, highly similar to Human ENO2 gene for neuron specific (gamma) enolase P
AK312402.1 Homo sapiens cDNA, FLJ92734, Homo sapiens enolase 2, (gamma, neuronal) (ENO2), mRNA P
X14327.1 Human mRNA for neurone specific gamma enolase (NSE), EC number=4.2.1.11 P
X13120.1 Human mRNA fragment for neurone-specific enolase P
AK295220.1 Homo sapiens cDNA FLJ50150 complete cds, highly similar to Gamma-enolase (EC 4.2.1.11) P

EST sequences (10 of 1495) [Show all sequences]

AA971391.1 Clone IMAGE:1584270 lung 3' read A
AA987275.1 Clone IMAGE:1605013 lung 3' read A
AA987656.1 Clone IMAGE:1604347 lung 3' read A
AA988680.1 Clone IMAGE:1593462 kidney 3' read
AI002552.1 Clone IMAGE:1593640 kidney 3' read A
AI005189.1 Clone IMAGE:1632181 mammary gland 3' read A
AA928093.1 Clone IMAGE:1563556 mixed 3' read A
AI052757.1 Clone IMAGE:1671968 uncharacterized tissue 3' read A
R20685.1 Clone IMAGE:35850 brain 5' read P
AI089418.1 Clone IMAGE:1685744 brain 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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