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UGID:137969     UniGene Hs.50640     Homo sapiens (human)   SOCS1
Suppressor of cytokine signaling 1 (SOCS1)

Human protein-coding gene SOCS1. Represented by 198 ESTs from 56 cDNA libraries. EST representation biased toward fetus. Corresponds to reference sequence NM_003745.1. [UniGene 137969 - Hs.50640]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003736.1 SOCS1 gene product H. sapiens 100.0 210
XP_003916584.1 PREDICTED: suppressor of cytokine signaling 1 P. anubis 99.5 212
XP_001141793.1 PREDICTED: suppressor of cytokine signaling 1 P. troglodytes 99.5 210
NP_001258532.1 suppressor of cytokine signaling 1 M. musculus 97.6 211
NP_001153160.1 suppressor of cytokine signaling 1 X. laevis 58.3 210
Other hits (2 of 15) [Show all]SpeciesId(%)Len(aa)
XP_001104595.1 PREDICTED: suppressor of cytokine signaling 1 isoform 2 M. mulatta 99.1 214
XP_002711838.1 PREDICTED: suppressor of cytokine signaling 1-like, partial O. cuniculus 98.8 161

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: fetus [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: ovary; lung; mixed; lymph node; uncharacterized tissue; heart; pancreas; kidney; brain; intestine; placenta; skin; prostate; cervix; muscle; thymus; lymph; embryonic tissue; eye; spleen; testis; uterus; thyroid; pharynx; bone
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16p13.13
UniSTS entry: Chr 16 RH91351
UniSTS entry: Chr 16 PMC298718P1
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

AK127621.1 Homo sapiens cDNA FLJ45719 fis, clone FELNG2001953, highly similar to Suppressor of cytokine signaling 1 P
NM_003745.1 Homo sapiens suppressor of cytokine signaling 1 (SOCS1), mRNA P
U88326.1 Human suppressor of cytokine signalling-1 (SOCS-1) mRNA, complete cds PA
AB000676.1 Homo sapiens mRNA for JAB, partial cds PA
AB005043.1 Homo sapiens mRNA for STAT induced STAT inhibitor-1, complete cds P
AB000734.1 Homo sapiens mRNA for TIP3, complete cds P

EST sequences (10 of 198) [Show all sequences]

AA992900.1 Clone IMAGE:1624220 embryonic tissue 3' read
AA946696.1 Clone IMAGE:1372190 lymph node 3' read
AI041923.1 Clone IMAGE:1664606 skin 3' read
AI042065.1 Clone IMAGE:1660725 mixed 3' read
AI056051.1 Clone IMAGE:1659368 embryonic tissue 3' read P
AI057177.1 Clone IMAGE:1671913 uncharacterized tissue 3' read
AA948230.1 Clone IMAGE:1588156 uncharacterized tissue 3' read A
AI079449.1 Clone IMAGE:1680501 skin 3' read
AI094290.1 Clone IMAGE:1692325 heart 3' read
AI094927.1 Clone IMAGE:1687122 brain 3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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