NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:137969     UniGene Hs.50640     Homo sapiens (human)   SOCS1
Suppressor of cytokine signaling 1 (SOCS1)

Human protein-coding gene SOCS1. Represented by 198 ESTs from 56 cDNA libraries. EST representation biased toward fetus. Corresponds to reference sequence NM_003745.1. [UniGene 137969 - Hs.50640]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003736.1 SOCS1 gene product H. sapiens 100.0 210
XP_003916584.1 PREDICTED: suppressor of cytokine signaling 1 P. anubis 99.5 212
XP_001141793.1 PREDICTED: suppressor of cytokine signaling 1 P. troglodytes 99.5 210
NP_001258532.1 suppressor of cytokine signaling 1 M. musculus 97.6 211
NP_001153160.1 suppressor of cytokine signaling 1 X. laevis 58.3 210
Other hits (2 of 15) [Show all]SpeciesId(%)Len(aa)
XP_001104595.1 PREDICTED: suppressor of cytokine signaling 1 isoform 2 M. mulatta 99.1 214
XP_002711838.1 PREDICTED: suppressor of cytokine signaling 1-like, partial O. cuniculus 98.8 161

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: fetus [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: ovary; lung; mixed; lymph node; uncharacterized tissue; heart; pancreas; kidney; brain; intestine; placenta; skin; prostate; cervix; muscle; thymus; lymph; embryonic tissue; eye; spleen; testis; uterus; thyroid; pharynx; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16p13.13
UniSTS entry: Chr 16 RH91351
UniSTS entry: Chr 16 PMC298718P1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

AK127621.1 Homo sapiens cDNA FLJ45719 fis, clone FELNG2001953, highly similar to Suppressor of cytokine signaling 1 P
NM_003745.1 Homo sapiens suppressor of cytokine signaling 1 (SOCS1), mRNA P
U88326.1 Human suppressor of cytokine signalling-1 (SOCS-1) mRNA, complete cds PA
AB000676.1 Homo sapiens mRNA for JAB, partial cds PA
AB005043.1 Homo sapiens mRNA for STAT induced STAT inhibitor-1, complete cds P
AB000734.1 Homo sapiens mRNA for TIP3, complete cds P

EST sequences (10 of 198) [Show all sequences]

AA992900.1 Clone IMAGE:1624220 embryonic tissue 3' read
AA946696.1 Clone IMAGE:1372190 lymph node 3' read
AI041923.1 Clone IMAGE:1664606 skin 3' read
AI042065.1 Clone IMAGE:1660725 mixed 3' read
AI056051.1 Clone IMAGE:1659368 embryonic tissue 3' read P
AI057177.1 Clone IMAGE:1671913 uncharacterized tissue 3' read
AA948230.1 Clone IMAGE:1588156 uncharacterized tissue 3' read A
AI079449.1 Clone IMAGE:1680501 skin 3' read
AI094290.1 Clone IMAGE:1692325 heart 3' read
AI094927.1 Clone IMAGE:1687122 brain 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help