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UGID:720813     UniGene Hs.505654     Homo sapiens (human)   ITGA5
Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (ITGA5)

Human protein-coding gene ITGA5. Represented by 1000 ESTs from 297 cDNA libraries. Corresponds to reference sequence NM_002205.2. [UniGene 720813 - Hs.505654]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003313671.2 PREDICTED: LOW QUALITY PROTEIN: integrin alpha-5 P. troglodytes 100.0 1099
NP_002196.2 ITGA5 gene product H. sapiens 100.0 1048
XP_003906547.1 PREDICTED: integrin alpha-5 P. anubis 99.8 1097
NP_034707.3 Itga5 gene product M. musculus 94.8 1052
NP_001081072.1 integrin alpha-5 precursor X. laevis 71.9 1036
NP_001004288.1 integrin alpha-5 D. rerio 61.5 1032
NP_728021.2 inflated, isoform C D. melanogaster 45.5 176
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
XP_001110116.2 PREDICTED: integrin alpha-5 M. mulatta 99.3 1063
XP_001504621.3 PREDICTED: integrin alpha-5 E. caballus 97.9 1055

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; uterus; umbilical cord; lung; brain; testis; embryonic tissue; mixed; vascular; uncharacterized tissue; kidney; intestine; spinal cord; mouth; skin; adipose tissue; thymus; muscle; connective tissue; bone marrow; bladder; eye; liver; larynx; spleen; bone; pancreas; stomach; cervix; prostate; heart; trachea; ovary; mammary gland; blood; parathyroid; thyroid; amniotic fluid; epididymis; esophagus; ascites; ganglia; adrenal gland
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q11-q13
UniSTS entry: Chr 12 STS-X06256
UniSTS entry: Chr 12 RH47986
UniSTS entry: Chr 15 Rnu2
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_002205.2 Homo sapiens integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (ITGA5), mRNA PA
AY429549.1 Homo sapiens ITGA5v_1 mRNA sequence; alternatively spliced P
M13918.2 Homo sapiens fibronectin receptor alpha-subunit precursor (ITGA5) mRNA, partial cds P
BC008786.2 Homo sapiens integrin, alpha 5 (fibronectin receptor, alpha polypeptide), mRNA (cDNA clone MGC:3697 IMAGE:3629647), complete cds PA
X06256.1 Human mRNA for integrin alpha 5 subunit PA
AK291570.1 Homo sapiens cDNA FLJ77742 complete cds, highly similar to Homo sapiens integrin, alpha 5 (fibronectin receptor, alpha polypeptide), mRNA P
AK311051.1 Homo sapiens cDNA, FLJ18093 P
AK312414.1 Homo sapiens cDNA, FLJ92752, highly similar to Homo sapiens integrin, alpha 5 (fibronectin receptor, alphapolypeptide) (ITGA5), mRNA P
AK304696.1 Homo sapiens cDNA FLJ50382 complete cds, moderately similar to Integrin alpha-5 precursor P

EST sequences (10 of 1000) [Show all sequences]

AA991891.1 Clone IMAGE:1611226 uncharacterized tissue 3' read A
AI026049.1 Clone IMAGE:1647255 parathyroid 3' read A
AI033667.1 Clone IMAGE:1647616 parathyroid 3' read
AI039264.1 Clone IMAGE:1658118 embryonic tissue 3' read A
AI042429.1 Clone IMAGE:1665046 skin 3' read A
AI077734.1 Clone IMAGE:1663748 skin 3' read
AI077745.1 Clone IMAGE:1663749 skin 3' read
AI085688.1 Clone IMAGE:1680814 skin 3' read A
AI160180.1 Clone IMAGE:1705185 heart 3' read A
BX091686.1 Clone IMAGp998H16127_;_IMAGE:126399 mixed

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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