NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:716783     UniGene Hs.501624     Homo sapiens (human)   SIGIRR
Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (SIGIRR)

Human protein-coding gene SIGIRR. Represented by 222 ESTs from 113 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 716783 - Hs.501624]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_068577.2 SIGIRR gene product H. sapiens 100.0 409
NP_075546.2 Sigirr gene product M. musculus 88.5 408
NP_001091720.1 sigirr gene product D. rerio 52.4 404
Other hits (2 of 17) [Show all]SpeciesId(%)Len(aa)
XP_003909363.1 PREDICTED: single Ig IL-1-related receptor P. anubis 98.3 409
XP_001148349.2 PREDICTED: LOW QUALITY PROTEIN: single Ig IL-1-related receptor P. troglodytes 97.8 408

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; mixed; lung; intestine; blood; liver; eye; prostate; brain; embryonic tissue; esophagus; cervix; adrenal gland; spleen; testis; vascular; heart; connective tissue; thymus; skin; uterus; placenta; stomach; pancreas; ovary; adipose tissue; bone marrow; bladder; parathyroid; bone; nerve; ganglia; lymph node; kidney
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11p15.5
UniSTS entry: Chr 11 SHGC-64262
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AY358342.1 Homo sapiens clone DNA38649 SIGIRR (UNQ301) mRNA, complete cds P
AK172830.1 Homo sapiens cDNA FLJ23991 fis, clone HRC08504, highly similar to Homo sapiens single Ig IL-1R-related molecule (SIGIRR) PA
CR457338.1 Homo sapiens full open reading frame cDNA clone RZPDo834H0613D for gene SIGIRR, single Ig IL-1R-related molecule; complete cds, incl. stopcodon P
AK025099.1 Homo sapiens cDNA: FLJ21446 fis, clone COL04458 PA
BC106007.1 Homo sapiens single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, mRNA (cDNA clone MGC:110992 IMAGE:6092503), complete cds PA
NM_021805.2 Homo sapiens single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (SIGIRR), transcript variant 3, mRNA PA
BC003591.1 Homo sapiens single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, mRNA (cDNA clone MGC:4338 IMAGE:2821373), complete cds PA
BC025953.1 Homo sapiens single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, mRNA (cDNA clone MGC:39141 IMAGE:3939162), complete cds PA
AK093427.1 Homo sapiens cDNA FLJ36108 fis, clone TESTI2021895, moderately similar to Mus musculus toll/interleukin-1 receptor 8 (TIR8) mRNA P
NM_001135054.1 Homo sapiens single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (SIGIRR), transcript variant 1, mRNA PA
NM_001135053.1 Homo sapiens single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (SIGIRR), transcript variant 2, mRNA PA

EST sequences (10 of 222) [Show all sequences]

AA961817.1 Clone IMAGE:1598431 uncharacterized tissue 3' read A
AA923298.1 Clone IMAGE:1550706 uncharacterized tissue 3' read
AI052311.1 Clone IMAGE:1673423 mixed 3' read PA
CB048698.1 Clone IMAGE:3270939 prostate 3' read A
CB048699.1 Clone IMAGE:3270939 prostate 5' read A
CB120060.1 Clone L5HLK1s1-2-C03 liver 5' read P
CB137003.1 Clone L6ChoCK0-25-A12 liver 5' read
CB138796.1 Clone L6ChoCK0-32-H06 liver 5' read P
AI245859.1 Clone IMAGE:1870715 kidney 3' read A
AI284596.1 Clone IMAGE:1964369 ovary 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help