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UGID:714648     UniGene Hs.499489     Homo sapiens (human)   MARCH8
Membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase (MARCH8)

Human protein-coding gene MARCH8. Represented by 287 ESTs from 134 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 714648 - Hs.499489]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_659458.2 MARCH8 gene product H. sapiens 100.0 290
NP_082196.1 March8 gene product M. musculus 95.1 285
NP_001088241.1 E3 ubiquitin-protein ligase MARCH8 X. laevis 92.5 254
NP_001154907.1 E3 ubiquitin-protein ligase MARCH8 isoform 1 D. rerio 87.9 281
NP_648305.1 CG4080, isoform A D. melanogaster 55.8 165
Other hits (2 of 36) [Show all]SpeciesId(%)Len(aa)
XP_001159410.1 PREDICTED: uncharacterized protein LOC450431 isoform 3 P. troglodytes 98.2 572
XP_001102718.2 PREDICTED: e3 ubiquitin-protein ligase MARCH8-like isoform 2 M. mulatta 97.7 572

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; mixed; muscle; cervix; prostate; larynx; eye; lymph node; pancreas; ovary; embryonic tissue; uterus; mammary gland; uncharacterized tissue; thymus; esophagus; liver; parathyroid; placenta; skin; pituitary gland; vascular; mouth; lymph; connective tissue; spinal cord; tonsil; stomach; bone marrow; lung; blood; intestine; kidney; ascites; bone; adipose tissue; pharynx; heart
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q11.21
UniSTS entry: Chr 10 SGC30405 [Map Viewer]
UniSTS entry: Chr 10 RH68975
UniSTS entry: Chr 10 RH92176
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AK125414.1 Homo sapiens cDNA FLJ43425 fis, clone OCBBF2027197
BC066988.1 Homo sapiens membrane-associated ring finger (C3HC4) 8, mRNA (cDNA clone MGC:87645 IMAGE:5267214), complete cds PA
NM_001002266.1 Homo sapiens membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase (MARCH8), transcript variant 3, mRNA PA
NM_001002265.1 Homo sapiens membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase (MARCH8), transcript variant 1, mRNA PA
AK025472.1 Homo sapiens cDNA: FLJ21819 fis, clone HEP01185 A
AK057289.1 Homo sapiens cDNA FLJ32727 fis, clone TESTI2001008 P
AK313340.1 Homo sapiens cDNA, FLJ93862, highly similar to Homo sapiens cellular modulator of immune recognition (c-MIR), mRNA P
AK307667.1 Homo sapiens cDNA, FLJ97615 PA
BC025394.2 Homo sapiens membrane-associated ring finger (C3HC4) 8, mRNA (cDNA clone MGC:26766 IMAGE:4830278), complete cds PA
NM_145021.4 Homo sapiens membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase (MARCH8), transcript variant 2, mRNA PA
AL833316.1 Homo sapiens mRNA; cDNA DKFZp313K127 (from clone DKFZp313K127) PA

EST sequences (10 of 287) [Show all sequences]

AI004637.1 Clone IMAGE:1626056 mixed 3' read
AI022298.1 Clone IMAGE:1652250 mixed 3' read A
AI040127.1 Clone IMAGE:1655774 mixed 3' read A
AI076425.1 Clone IMAGE:1675566 mixed 3' read A
AI081010.1 Clone IMAGE:1652968 mixed 3' read A
AI088943.1 Clone IMAGE:1634664 mixed 3' read A
AI090716.1 Clone IMAGE:1640142 testis 3' read A
AI127690.1 Clone IMAGE:1710359 uterus 3' read A
BX103164.1 Clone IMAGp998N14391_;_IMAGE:202957 mixed
AI161178.1 Clone IMAGE:1703563 brain 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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