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UGID:137871     UniGene Hs.49774     Homo sapiens (human)   PTPRM
Protein tyrosine phosphatase, receptor type, M (PTPRM)

Human protein-coding gene PTPRM. Represented by 369 ESTs from 171 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 137871 - Hs.49774]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003315855.1 PREDICTED: receptor-type tyrosine-protein phosphatase mu isoform 2 P. troglodytes 100.0 1464
NP_001098714.1 PTPRM gene product H. sapiens 100.0 1464
XP_003914220.1 PREDICTED: receptor-type tyrosine-protein phosphatase mu-like, partial P. anubis 99.8 1209
NP_033010.2 Ptprm gene product M. musculus 98.7 1451
NP_001002299.1 ptprub gene product D. rerio 60.8 1429
NP_001081987.1 protein tyrosine phosphatase, receptor type, F precursor X. laevis 53.2 594
NP_001021944.1 Protein PTP-3, isoform c C. elegans 52.8 398
NP_001246094.1 Leukocyte-antigen-related-like, isoform D D. melanogaster 50.8 573
Other hits (2 of 37) [Show all]SpeciesId(%)Len(aa)
XP_537326.3 PREDICTED: receptor-type tyrosine-protein phosphatase mu isoform 1 C. lupus familiaris 99.5 1441
XP_002713623.1 PREDICTED: protein tyrosine phosphatase, receptor type, M O. cuniculus 99.3 1446

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; thyroid; uncharacterized tissue; placenta; lung; pancreas; heart; parathyroid; amniotic fluid; vascular; thymus; eye; uterus; kidney; skin; embryonic tissue; spinal cord; connective tissue; liver; ascites; bone; prostate; mixed; mammary gland; pituitary gland; muscle; trachea; pharynx; cervix; nerve; bladder; intestine; lymph node; ovary; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 18
Map position: 18p11.2
UniSTS entry: Chr 18 D18S906E
UniSTS entry: Chr 18 WI-9017 [Map Viewer]
UniSTS entry: Chr 18 PTPRM
UniSTS entry: Chr 18 D18S933E
UniSTS entry: G10607
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

BC051651.1 Homo sapiens protein tyrosine phosphatase, receptor type, M, mRNA (cDNA clone MGC:51345 IMAGE:5274244), complete cds P
NM_002845.3 Homo sapiens protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 2, mRNA PA
AF403226.1 Homo sapiens Shinc-5 mRNA, partial sequence
X58288.1 H.sapiens hR-PTPu gene for protein tyrosine phosphatase P
BC151842.1 Homo sapiens protein tyrosine phosphatase, receptor type, M, mRNA (cDNA clone MGC:166994 IMAGE:8860327), complete cds PA
NM_001105244.1 Homo sapiens protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 1, mRNA PA
AK294492.1 Homo sapiens cDNA FLJ55898 complete cds, highly similar to Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) P
AK303652.1 Homo sapiens cDNA FLJ58084 complete cds, highly similar to Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) P
BC040543.1 Homo sapiens protein tyrosine phosphatase, receptor type, M, mRNA (cDNA clone IMAGE:5271160), complete cds PA

EST sequences (10 of 369) [Show all sequences]

AA887177.1 Clone IMAGE:1500746 kidney 3' read A
AI018789.1 Clone IMAGE:1639062 testis 3' read A
AI038911.1 Clone IMAGE:1664191 skin 3' read
AI040971.1 Clone IMAGE:1641782 testis 3' read PA
AI084839.1 Clone IMAGE:1654022 mixed 3' read
AI123984.1 Clone IMAGE:1694898 uterus 3' read A
AI129730.1 Clone IMAGE:1712103 uterus 3' read A
CB051573.1 Clone IMAGE:3289772 uncharacterized tissue 3' read A
AI191744.1 Clone IMAGE:1733507 testis 3' read A
AA905293.1 Clone IMAGE:1506156 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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