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UGID:700943     UniGene Hs.485784     Homo sapiens (human)   SENP6
SUMO1/sentrin specific peptidase 6 (SENP6)

Human protein-coding gene SENP6. Represented by 452 ESTs from 218 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 700943 - Hs.485784]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_056386.2 SENP6 gene product H. sapiens 100.0 1111
XP_518592.3 PREDICTED: sentrin-specific protease 6 isoform 2 P. troglodytes 99.9 1111
NP_666115.2 Senp6 gene product M. musculus 87.8 1127
XP_002665676.2 PREDICTED: sentrin-specific protease 6 D. rerio 67.3 587
NP_001135831.1 SUMO1/sentrin specific peptidase 6 X. laevis 65.3 1101
Other hits (2 of 27) [Show all]SpeciesId(%)Len(aa)
XP_001113419.1 PREDICTED: sentrin-specific protease 6 M. mulatta 98.5 684
XP_003897868.1 PREDICTED: sentrin-specific protease 6-like isoform 2 P. anubis 98.1 692

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; embryonic tissue; lung; placenta; uncharacterized tissue; uterus; ovary; parathyroid; liver; pituitary gland; blood; intestine; bone marrow; larynx; vascular; trachea; thymus; skin; mixed; lymph; mouth; eye; kidney; lymph node; prostate; heart; pancreas; mammary gland; connective tissue; nerve; salivary gland; ear; bone; muscle; thyroid; bladder; adipose tissue; amniotic fluid; ascites; umbilical cord; adrenal gland
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6q13-q14.3
UniSTS entry: Chr 6 D6S1339 [Map Viewer]
UniSTS entry: Chr 6 D6S1226E
UniSTS entry: Chr 6 RH69973 [Map Viewer]
UniSTS entry: Chr 6 SHGC-33979 [Map Viewer]
UniSTS entry: Chr 6 WI-11925 [Map Viewer]
UniSTS entry: Chr 6 SENP6__3808
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AB018340.2 Homo sapiens mRNA for KIAA0797 protein, partial cds P
AK126921.1 Homo sapiens cDNA FLJ44973 fis, clone BRAWH3001638, highly similar to Sentrin-specific protease 6 (EC 3.4.22.-) P
AK001406.1 Homo sapiens cDNA FLJ10544 fis, clone NT2RP2001601, highly similar to Sentrin-specific protease 6 (EC 3.4.22.-) P
NM_015571.2 Homo sapiens SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 1, mRNA PA
AF196304.1 Homo sapiens SUMO-1-specific protease (SSP1) mRNA, complete cds P
AK021949.1 Homo sapiens cDNA FLJ11887 fis, clone HEMBA1007224, highly similar to Sentrin-specific protease 6 (EC 3.4.22.-) P
AF307849.1 Homo sapiens sentrin-specific protease SENP6 mRNA, complete cds P
NM_001100409.1 Homo sapiens SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 2, mRNA PA
BC028583.1 Homo sapiens SUMO1/sentrin specific peptidase 6, mRNA (cDNA clone MGC:26784 IMAGE:4838569), complete cds PA
AK096455.1 Homo sapiens cDNA FLJ39136 fis, clone NTONG2008944, highly similar to Homo sapiens sentrin-specific protease SENP6 mRNA P
AF306508.1 Homo sapiens SUMO-1 specific protease FKSG6 mRNA, complete cds P

EST sequences (10 of 452) [Show all sequences]

AA962641.1 Clone IMAGE:1553675 kidney 3' read A
AA984354.1 Clone IMAGE:1629832 brain 3' read
AA906929.1 Clone IMAGE:1521672 lung 3' read A
AI027166.1 Clone IMAGE:1649541 parathyroid 3' read A
AI028194.1 Clone IMAGE:1645132 testis 3' read PA
AI032298.1 Clone IMAGE:1644187 testis 3' read PA
AI093445.1 Clone IMAGE:1695648 uterus 3' read A
AI096700.1 Clone IMAGE:1707462 heart 3' read P
AA910527.1 Clone IMAGE:1517975 uncharacterized tissue 3' read A
AI130810.1 Clone IMAGE:1709117 heart 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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