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UGID:700392     UniGene Hs.485233     Homo sapiens (human)   MAPK14
Mitogen-activated protein kinase 14 (MAPK14)

Human protein-coding gene MAPK14. Represented by 426 ESTs from 219 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 700392 - Hs.485233]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003897563.1 PREDICTED: mitogen-activated protein kinase 14 isoform 2 P. anubis 100.0 359
NP_001009065.1 MAPK14 gene product P. troglodytes 100.0 359
NP_001306.1 MAPK14 gene product H. sapiens 100.0 359
NP_001095644.1 MAPK14 gene product B. taurus 100.0 359
NP_001136366.1 MAPK14 gene product O. aries 100.0 359
XP_002714692.1 PREDICTED: mitogen-activated protein kinase 14 isoform 2 O. cuniculus 100.0 359
XP_001494769.3 PREDICTED: mitogen-activated protein kinase 14 E. caballus 100.0 282
NP_001161980.1 Mapk14 gene product M. musculus 99.7 359
NP_112282.2 Mapk14 gene product R. norvegicus 99.7 359
NP_001003206.1 MAPK14 gene product C. lupus familiaris 99.7 359
XP_003356663.1 PREDICTED: mitogen-activated protein kinase 14 S. scrofa 99.7 359
XP_001112423.2 PREDICTED: mitogen-activated protein kinase 14-like, partial M. mulatta 99.7 310
NP_571797.1 mapk14a gene product D. rerio 95.0 360
NP_001080300.1 mitogen-activated protein kinase 14 X. laevis 94.4 358
NP_477361.1 p38b D. melanogaster 80.5 353
NP_501365.1 Protein PMK-1 C. elegans 77.6 361
XP_962163.2 mitogen-activated protein kinase sty1 N. crassa 56.7 337
NP_192046.1 mitogen-activated protein kinase 4 A. thaliana 56.2 363
XP_001690850.1 mitogen-activated protein kinase 6 C. reinhardtii 52.3 342
NP_011554.3 Kss1p S. cerevisiae 50.3 358
Other hits (2 of 57) [Show all]SpeciesId(%)Len(aa)
XP_001369941.1 PREDICTED: mitogen-activated protein kinase 14 isoform 1 M. domestica 99.4 359
XP_003226524.1 PREDICTED: mitogen-activated protein kinase 14-like isoform 2 A. carolinensis 98.3 359

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; placenta; testis; intestine; uterus; bone marrow; mouth; thymus; lymph node; blood; mixed; mammary gland; embryonic tissue; heart; eye; kidney; lung; pancreas; bladder; vascular; trachea; stomach; connective tissue; liver; cervix; lymph; epididymis; ascites; bone; larynx; skin; prostate; ovary; spleen; adipose tissue; ear; muscle
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6p21.3-p21.2
UniSTS entry: Chr 6 RH46846
UniSTS entry: Chr 6 G20844
UniSTS entry: Chr 6 A006I20 [Map Viewer]
UniSTS entry: Chr 6 STS-L35253
UniSTS entry: fd03e12.y1
UniSTS entry: Chr 6 D6S1848 [Map Viewer]
UniSTS entry: Chr 6 D6S1210E [Map Viewer]
UniSTS entry: Chr 6 RH80957
UniSTS entry: Chr 6 MAPK14_184
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

BT006933.1 Homo sapiens mitogen-activated protein kinase 14 mRNA, complete cds P
NM_001315.2 Homo sapiens mitogen-activated protein kinase 14 (MAPK14), transcript variant 1, mRNA PA
AF100544.1 Homo sapiens stress-activated protein kinase 2a (CSBP) mRNA, complete cds P
CR536505.1 Homo sapiens full open reading frame cDNA clone RZPDo834D0720D for gene MAPK14, mitogen-activated protein kinase 14; complete cds, incl. stopcodon P
L35263.1 Human CSaids binding protein (CSBP1) mRNA, complete cds P
L35264.1 Human CSaids binding protein (CSBP2) mRNA, complete cds P
BC000092.1 Homo sapiens mitogen-activated protein kinase 14, mRNA (cDNA clone MGC:2183 IMAGE:3505234), complete cds PA
AK291709.1 Homo sapiens cDNA FLJ76665 complete cds, highly similar to Homo sapiens mitogen-activated protein kinase 14 (MAPK14), transcript variant 2, mRNA P
AB074150.1 Homo sapiens Exip mRNA for Alternative spliced variant of p38alpha EXIP, complete cds P
NM_139014.2 Homo sapiens mitogen-activated protein kinase 14 (MAPK14), transcript variant 4, mRNA PA
NM_139013.2 Homo sapiens mitogen-activated protein kinase 14 (MAPK14), transcript variant 3, mRNA PA
NM_139012.2 Homo sapiens mitogen-activated protein kinase 14 (MAPK14), transcript variant 2, mRNA PA
BC031574.1 Homo sapiens mitogen-activated protein kinase 14, mRNA (cDNA clone MGC:34610 IMAGE:5181064), complete cds PA
AK303414.1 Homo sapiens cDNA FLJ58214 complete cds, highly similar to Mitogen-activated protein kinase 14 (EC2.7.11.24) P
FJ032368.1 Homo sapiens mitogen-activated protein kinase 14 isoform 5 (MAPK14) mRNA, complete cds P
FJ032367.1 Homo sapiens mitogen-activated protein kinase 14 isoform 4 (MAPK14) mRNA, complete cds P
Z25432.1 H.sapiens protein-serine/threonine kinase gene, complete CDS

EST sequences (10 of 426) [Show all sequences]

AA993775.1 Clone IMAGE:1621701 testis 3' read A
AA948637.1 Clone IMAGE:1588534 kidney 3' read A
AI082645.1 Clone IMAGE:1669873 brain 3' read A
AI089582.1 Clone IMAGE:1695876 uterus 3' read
AI138777.1 Clone IMAGE:1737950 testis 3' read
AI140527.1 Clone IMAGE:1652774 mixed 3' read A
CB053619.1 Clone IMAGE:3290984 uncharacterized tissue 3' read A
CB053620.1 Clone IMAGE:3290984 uncharacterized tissue 5' read
AI148543.1 Clone IMAGE:1714781 placenta 3' read A
AI151531.1 Clone IMAGE:1715909 placenta 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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