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UGID:697721     UniGene Hs.482562     Homo sapiens (human)   F2R
Coagulation factor II (thrombin) receptor (F2R)

Human protein-coding gene F2R. Represented by 321 ESTs from 124 cDNA libraries. Corresponds to reference sequence NM_001992.3. [UniGene 697721 - Hs.482562]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001983.2 F2R gene product H. sapiens 100.0 424
XP_526888.3 PREDICTED: proteinase-activated receptor 1 P. troglodytes 99.8 424
XP_001106136.1 PREDICTED: proteinase-activated receptor 1 M. mulatta 99.5 424
NP_034299.2 F2r gene product M. musculus 85.3 429
NP_001079252.1 proteinase-activated receptor 1 precursor X. laevis 63.8 411
NP_001108318.1 f2r gene product D. rerio 55.8 371
Other hits (2 of 18) [Show all]SpeciesId(%)Len(aa)
XP_003899888.1 PREDICTED: proteinase-activated receptor 1 P. anubis 99.0 398
XP_001504007.2 PREDICTED: proteinase-activated receptor 1-like E. caballus 92.2 397

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; embryonic tissue; vascular; kidney; lung; ovary; umbilical cord; spleen; placenta; connective tissue; mammary gland; intestine; mouth; trachea; skin; mixed; bone marrow; eye; uncharacterized tissue; adrenal gland; bladder; uterus; stomach; pancreas; thymus; lymph; prostate; liver; heart; bone; thyroid; muscle; ascites
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5q13
UniSTS entry: Chr 1 D11S3316
UniSTS entry: Chr 5 WI-14632 [Map Viewer]
UniSTS entry: Chr 5 PMC98608P1
UniSTS entry: Chr 5 STS-N35000 [Map Viewer]
UniSTS entry: Chr 11 RH70343 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

BT007279.1 Homo sapiens coagulation factor II (thrombin) receptor mRNA, complete cds P
BC051909.1 Homo sapiens coagulation factor II (thrombin) receptor, mRNA (cDNA clone MGC:60377 IMAGE:6172703), complete cds PA
M62424.1 Human thrombin receptor mRNA, complete cds P
NM_001992.3 Homo sapiens coagulation factor II (thrombin) receptor (F2R), mRNA PA
AY771596.1 Homo sapiens cell proliferation-inducing protein 18 mRNA, complete cds A
BC002464.2 Homo sapiens coagulation factor II (thrombin) receptor, mRNA (cDNA clone MGC:1197 IMAGE:3343051), complete cds PA
AK314202.1 Homo sapiens cDNA, FLJ94928 P
AK308169.1 Homo sapiens cDNA, FLJ98117 P
AK297131.1 Homo sapiens cDNA FLJ55303 complete cds, highly similar to Proteinase-activated receptor 1 precursor P
BC016059.1 Homo sapiens coagulation factor II (thrombin) receptor, mRNA (cDNA clone IMAGE:4849569), with apparent retained intron A
S76625.1 thrombin receptor {clone A} [human, colon adenocarcinoma cells, mRNA Partial, 273 nt] P
M93111.1 Human endothelial cell-derived thrombin receptor cDNA, 5' additional sequence

EST sequences (10 of 321) [Show all sequences]

AI079831.1 Clone IMAGE:1659746 embryonic tissue 3' read A
AI123166.1 Clone IMAGE:1693645 heart 3' read P
BX106532.1 Clone IMAGp998C152008_;_IMAGE:813254 mixed
AI266626.1 Clone IMAGE:1891672 placenta 3' read A
R31226.1 Clone IMAGE:134315 placenta 5' read
AI278523.1 Clone IMAGE:1893127 placenta 3' read A
AI279688.1 Clone IMAGE:1891546 placenta 3' read A
AI351610.1 Clone IMAGE:1940195 embryonic tissue 3' read
AI356904.1 Clone IMAGE:2012901 brain 3' read
AI363879.1 Clone IMAGE:2016383 brain 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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