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UGID:695015     UniGene Hs.479856     Homo sapiens (human)   SPSB2
SplA/ryanodine receptor domain and SOCS box containing 2 (SPSB2)

Human protein-coding gene SPSB2. Represented by 109 ESTs from 82 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 695015 - Hs.479856]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_116030.1 SPSB2 gene product H. sapiens 100.0 262
XP_003313510.1 PREDICTED: LOW QUALITY PROTEIN: SPRY domain-containing SOCS box protein 2 P. troglodytes 99.6 262
NP_038567.1 Spsb2 gene product M. musculus 92.0 263
NP_001089239.1 splA/ryanodine receptor domain and SOCS box containing 4 X. laevis 60.4 244
XP_686153.2 PREDICTED: SPRY domain-containing SOCS box protein 4 D. rerio 59.0 255
NP_001246140.1 gustavus, isoform G D. melanogaster 54.2 251
NP_497320.2 Protein SPSB-2 C. elegans 46.9 239
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_534903.1 PREDICTED: SPRY domain-containing SOCS box protein 2 C. lupus familiaris 96.6 262
NP_001230244.1 SPSB2 gene product S. scrofa 96.2 262

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; embryonic tissue; mixed; uterus; uncharacterized tissue; kidney; ovary; pancreas; placenta; spleen; mammary gland; testis; connective tissue; esophagus; thymus; epididymis; bladder; tonsil; ascites; skin; eye; larynx; liver; lymph node; cervix; bone; intestine; pharynx; blood; thyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12p13.31
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

BC071933.1 Homo sapiens splA/ryanodine receptor domain and SOCS box containing 2, mRNA (cDNA clone MGC:88619 IMAGE:6302511), complete cds PA
BC002983.1 Homo sapiens splA/ryanodine receptor domain and SOCS box containing 2, mRNA (cDNA clone MGC:2519 IMAGE:3546861), complete cds PA
NM_032641.3 Homo sapiens splA/ryanodine receptor domain and SOCS box containing 2 (SPSB2), transcript variant 1, mRNA PA
AF403027.1 Homo sapiens SPRY domain-containing SOCS box protein SSB-2 mRNA, complete cds P
AK297963.1 Homo sapiens cDNA FLJ55414 complete cds, highly similar to SPRY domain-containing SOCS box protein 2 P
NM_001146316.1 Homo sapiens splA/ryanodine receptor domain and SOCS box containing 2 (SPSB2), transcript variant 2, mRNA PA

EST sequences (10 of 109) [Show all sequences]

AA864326.1 Clone IMAGE:1470665 uncharacterized tissue 3' read
AA987941.1 Clone IMAGE:1603420 lung 3' read
AA928380.1 Clone IMAGE:1553135 uncharacterized tissue 3' read
AI094663.1 Clone IMAGE:1670339 brain 3' read
AI241963.1 Clone IMAGE:1977367 brain 3' read
AI261656.1 Clone IMAGE:2028435 kidney 3' read A
AI291013.1 Clone IMAGE:1881362 lung 3' read
AI341418.1 Clone IMAGE:2009888 uncharacterized tissue 3' read
AI351622.1 Clone IMAGE:1940032 embryonic tissue 3' read
AI359227.1 Clone IMAGE:2012665 brain 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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