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UGID:694258     UniGene Hs.479099     Homo sapiens (human)   SORCS2
Sortilin-related VPS10 domain containing receptor 2 (SORCS2)

Human protein-coding gene SORCS2. Represented by 78 ESTs from 47 cDNA libraries. Corresponds to reference sequence NM_020777.2. [UniGene 694258 - Hs.479099]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_065828.2 SORCS2 gene product H. sapiens 100.0 1158
XP_003310293.2 PREDICTED: VPS10 domain-containing receptor SorCS2 P. troglodytes 99.8 1001
NP_112151.2 Sorcs2 gene product M. musculus 90.8 1158
XP_002662899.2 PREDICTED: VPS10 domain-containing receptor SorCS2-like D. rerio 76.4 1047
Other hits (2 of 18) [Show all]SpeciesId(%)Len(aa)
XP_003898487.1 PREDICTED: VPS10 domain-containing receptor SorCS2 P. anubis 97.1 867
XP_002804048.1 PREDICTED: VPS10 domain-containing receptor SorCS2-like M. mulatta 93.7 968

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; bladder; thymus; testis; uterus; blood; connective tissue; trachea; heart; eye; prostate; embryonic tissue; kidney; skin; muscle; lung; bone; mixed; mammary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4p16.1
UniSTS entry: Chr 4 SHGC-59838
UniSTS entry: Chr 4 G43673
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

AB037750.1 Homo sapiens mRNA for KIAA1329 protein, partial cds P
NM_020777.2 Homo sapiens sortilin-related VPS10 domain containing receptor 2 (SORCS2), mRNA PA
AK295629.1 Homo sapiens cDNA FLJ51207 complete cds, highly similar to VPS10 domain-containing receptor SorCS2 precursor P
AF286190.1 Homo sapiens VPS10 domain protein mRNA, partial cds P
BC035257.1 Homo sapiens sortilin-related VPS10 domain containing receptor 2, mRNA (cDNA clone IMAGE:4752718), partial cds A

EST sequences (10 of 78) [Show all sequences]

AA974248.1 Clone IMAGE:1585937 uncharacterized tissue 3' read A
AA993556.1 Clone IMAGE:1624654 embryonic tissue 3' read A
AI003491.1 Clone IMAGE:1699090 kidney 3' read A
T27123.1 Clone LLAB303G07 brain 3' read A
T27124.1 Clone LLAB303G07 brain 5' read
R19806.1 Clone IMAGE:34861 brain 5' read
BX110646.1 Clone IMAGp998N15138_;_IMAGE:25980 brain A
AI206155.1 Clone IMAGE:1942095 uncharacterized tissue 3' read P
R37251.1 Clone IMAGE:25980 brain 3' read A
R56444.1 Clone IMAGE:40982 brain 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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