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UGID:693038     UniGene Hs.477879     Homo sapiens (human)   H2AFX
H2A histone family, member X (H2AFX)

Human protein-coding gene H2AFX. Represented by 682 ESTs from 168 cDNA libraries. Corresponds to reference sequence NM_002105.2. [UniGene 693038 - Hs.477879]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_034566.1 H2afx gene product M. musculus 100.0 142
NP_001102761.1 H2afx gene product R. norvegicus 100.0 142
XP_001102040.1 PREDICTED: histone H2A.x-like isoform 2 M. mulatta 100.0 142
XP_003910863.1 PREDICTED: histone H2A.x-like P. anubis 100.0 142
NP_002096.1 H2AFX gene product H. sapiens 100.0 142
XP_853256.2 PREDICTED: histone H2A.x-like C. lupus familiaris 100.0 142
XP_003129998.2 PREDICTED: histone H2A.x-like S. scrofa 100.0 142
NP_001073248.1 H2AFX gene product B. taurus 100.0 142
XP_004016142.1 PREDICTED: histone H2A.x-like isoform 1 O. aries 100.0 142
XP_002722755.1 PREDICTED: H2A histone family, member X-like isoform 1 O. cuniculus 100.0 142
NP_957367.1 h2afx gene product D. rerio 96.5 141
NP_724343.1 histone H2A D. melanogaster 93.5 123
NP_001086099.1 histone H2A.x X. laevis 92.1 138
NP_505463.1 Protein HIS-35 C. elegans 90.5 126
XP_959442.1 histone H2A N. crassa 90.3 133
NP_010511.3 Hta1p S. cerevisiae 84.6 129
XP_001691545.1 histone H2A C. reinhardtii 83.0 128
NP_175517.1 histone H2A 10 A. thaliana 81.8 131
Other hits (2 of 56) [Show all]SpeciesId(%)Len(aa)
XP_001370540.1 PREDICTED: histone H2A.x M. domestica 99.3 144
XP_001512371.1 PREDICTED: histone H2A.x-like O. anatinus 99.3 141

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lymph node; mixed; brain; lung; ovary; embryonic tissue; intestine; eye; pancreas; skin; uncharacterized tissue; placenta; ascites; amniotic fluid; lymph; mouth; heart; uterus; pharynx; thyroid; kidney; stomach; prostate; bone; liver; blood; tonsil; muscle; salivary gland; mammary gland; testis; spleen; vascular; parathyroid; connective tissue; cervix
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q23.3
UniSTS entry: Chr 11 RH80367
UniSTS entry: Chr 11 D11S4378 [Map Viewer]
UniSTS entry: Chr 11 H2AFX
UniSTS entry: Chr 11 A004Z11 [Map Viewer]
UniSTS entry: Chr 11 G15876
UniSTS entry: Chr 12 STS-H53100
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

NM_002105.2 Homo sapiens H2A histone family, member X (H2AFX), mRNA PA
CR457079.1 Homo sapiens full open reading frame cDNA clone RZPDo834A117D for gene H2AFX, H2A histone family, member X; complete cds, incl. stopcodon P
BC004915.2 Homo sapiens H2A histone family, member X, mRNA (cDNA clone MGC:4759 IMAGE:3537648), complete cds PA
BC011694.2 Homo sapiens H2A histone family, member X, mRNA (cDNA clone MGC:19656 IMAGE:3139343), complete cds PA
BC013416.2 Homo sapiens H2A histone family, member X, mRNA (cDNA clone MGC:4703 IMAGE:3534359), complete cds PA
X14850.1 Human H2A.X mRNA encoding histone H2A.X P

EST sequences (10 of 682) [Show all sequences]

AA961041.1 Clone IMAGE:1578792 mixed 3' read
AA972427.1 Clone IMAGE:1582952 mixed 3' read
AA909952.1 Clone IMAGE:1542779 mixed 3' read
AI025238.1 Clone IMAGE:1641350 testis 3' read A
AA948456.1 Clone IMAGE:1561734 mixed 3' read
AA948512.1 Clone IMAGE:1560397 intestine 3' read
AI033349.1 Clone IMAGE:1655178 mixed 3' read A
AA928634.1 Clone IMAGE:1553015 uncharacterized tissue 3' read
AI052545.1 Clone IMAGE:1676605 embryonic tissue 3' read
AI073667.1 Clone IMAGE:1664359 skin 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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