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UGID:682066     UniGene Hs.466907     Homo sapiens (human)   CBLC
Cbl proto-oncogene, E3 ubiquitin protein ligase C (CBLC)

Human protein-coding gene CBLC. Represented by 50 ESTs from 28 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 682066 - Hs.466907]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_036248.3 CBLC gene product H. sapiens 100.0 473
NP_075713.3 Cblc gene product M. musculus 82.3 447
NP_001084790.1 E3 ubiquitin-protein ligase CBL-B-B X. laevis 60.5 395
NP_729382.1 Cbl, isoform A D. melanogaster 59.1 384
NP_001024798.1 Protein SLI-1, isoform c C. elegans 56.5 299
NP_001121724.2 zgc:172162 gene product D. rerio 55.8 448
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
XP_001109370.1 PREDICTED: signal transduction protein CBL-C-like M. mulatta 96.4 473
XP_003915739.1 PREDICTED: signal transduction protein CBL-C isoform 1 P. anubis 96.0 473

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lung; embryonic tissue; mammary gland; mixed; placenta; uterus; intestine; skin; brain; ascites; stomach; pancreas; larynx; uncharacterized tissue
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19q13.2
UniSTS entry: Chr 19 RH48807 [Map Viewer]
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

AB028645.1 Homo sapiens mRNA for Cbl-c, complete cds PA
NM_012116.3 Homo sapiens Cbl proto-oncogene, E3 ubiquitin protein ligase C (CBLC), transcript variant 1, mRNA PA
AF117646.1 Homo sapiens long CBL-3 protein (CBL-3) mRNA, alternatively spliced isoform, complete cds P
AF117647.1 Homo sapiens short CBL-3 protein (CBL-3) mRNA, alternatively spliced isoform, complete cds P
BC028915.1 Homo sapiens Cas-Br-M (murine) ecotropic retroviral transforming sequence c, mRNA (cDNA clone MGC:24886 IMAGE:4777669), complete cds PA
NM_001130852.1 Homo sapiens Cbl proto-oncogene, E3 ubiquitin protein ligase C (CBLC), transcript variant 2, mRNA PA

EST sequences (10 of 50) [Show all sequences]

AI344839.1 Clone IMAGE:2052256 lung 3' read A
AI344947.1 Clone IMAGE:2052292 lung 3' read A
AI345593.1 Clone IMAGE:2060451 lung 3' read
AI345656.1 Clone IMAGE:2060479 lung 3' read A
AI368245.1 Clone IMAGE:1991273 uterus 3' read PA
AI660567.1 Clone IMAGE:2346244 intestine 3' read PA
AI690580.1 Clone IMAGE:2207612 uterus 3' read PA
AI758472.1 Clone IMAGE:2278445 uterus 3' read A
AI801220.1 Clone IMAGE:2185170 stomach 3' read A
AW268166.1 Clone IMAGE:2767670 lung 3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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