NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:682066     UniGene Hs.466907     Homo sapiens (human)   CBLC
Cbl proto-oncogene, E3 ubiquitin protein ligase C (CBLC)

Human protein-coding gene CBLC. Represented by 50 ESTs from 28 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 682066 - Hs.466907]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_036248.3 CBLC gene product H. sapiens 100.0 473
NP_075713.3 Cblc gene product M. musculus 82.3 447
NP_001084790.1 E3 ubiquitin-protein ligase CBL-B-B X. laevis 60.5 395
NP_729382.1 Cbl, isoform A D. melanogaster 59.1 384
NP_001024798.1 Protein SLI-1, isoform c C. elegans 56.5 299
NP_001121724.2 zgc:172162 gene product D. rerio 55.8 448
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
XP_001109370.1 PREDICTED: signal transduction protein CBL-C-like M. mulatta 96.4 473
XP_003915739.1 PREDICTED: signal transduction protein CBL-C isoform 1 P. anubis 96.0 473

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lung; embryonic tissue; mammary gland; mixed; placenta; uterus; intestine; skin; brain; ascites; stomach; pancreas; larynx; uncharacterized tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19q13.2
UniSTS entry: Chr 19 RH48807 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

AB028645.1 Homo sapiens mRNA for Cbl-c, complete cds PA
NM_012116.3 Homo sapiens Cbl proto-oncogene, E3 ubiquitin protein ligase C (CBLC), transcript variant 1, mRNA PA
AF117646.1 Homo sapiens long CBL-3 protein (CBL-3) mRNA, alternatively spliced isoform, complete cds P
AF117647.1 Homo sapiens short CBL-3 protein (CBL-3) mRNA, alternatively spliced isoform, complete cds P
BC028915.1 Homo sapiens Cas-Br-M (murine) ecotropic retroviral transforming sequence c, mRNA (cDNA clone MGC:24886 IMAGE:4777669), complete cds PA
NM_001130852.1 Homo sapiens Cbl proto-oncogene, E3 ubiquitin protein ligase C (CBLC), transcript variant 2, mRNA PA

EST sequences (10 of 50) [Show all sequences]

AI344839.1 Clone IMAGE:2052256 lung 3' read A
AI344947.1 Clone IMAGE:2052292 lung 3' read A
AI345593.1 Clone IMAGE:2060451 lung 3' read
AI345656.1 Clone IMAGE:2060479 lung 3' read A
AI368245.1 Clone IMAGE:1991273 uterus 3' read PA
AI660567.1 Clone IMAGE:2346244 intestine 3' read PA
AI690580.1 Clone IMAGE:2207612 uterus 3' read PA
AI758472.1 Clone IMAGE:2278445 uterus 3' read A
AI801220.1 Clone IMAGE:2185170 stomach 3' read A
AW268166.1 Clone IMAGE:2767670 lung 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help