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UGID:137390     UniGene Hs.46578     Homo sapiens (human)   DOCK10
Dedicator of cytokinesis 10 (DOCK10)

Human protein-coding gene DOCK10. Represented by 158 ESTs from 97 cDNA libraries. Corresponds to reference sequence NM_014689.2. [UniGene 137390 - Hs.46578]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_055504.2 DOCK10 gene product H. sapiens 100.0 2185
XP_516126.2 PREDICTED: dedicator of cytokinesis protein 10 isoform 2 P. troglodytes 100.0 2185
NP_780500.2 dedicator of cytokinesis protein 10 M. musculus 96.3 2186
NP_001104199.1 dedicator of cytokinesis 10 X. laevis 87.2 429
XP_001341048.4 PREDICTED: dedicator of cytokinesis protein 10-like D. rerio 76.0 2126
NP_609125.3 CG42533 D. melanogaster 52.8 640
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_003908065.1 PREDICTED: dedicator of cytokinesis protein 10-like P. anubis 99.3 1509
XP_002799128.1 PREDICTED: dedicator of cytokinesis protein 10-like M. mulatta 97.9 2210

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; uncharacterized tissue; blood; spinal cord; uterus; lymph node; vascular; embryonic tissue; pancreas; intestine; ovary; mammary gland; testis; larynx; connective tissue; skin; lung; prostate; thymus; bone marrow; eye; heart; spleen; kidney; bone; muscle; ganglia; adipose tissue
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q36.2
UniSTS entry: Chr 2 STS-AA039469
UniSTS entry: Chr 2 MARC_21678-21679:1033416202:1
UniSTS entry: Chr 1 D1S1425
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

AB014594.2 Homo sapiens mRNA for KIAA0694 protein, partial cds P
AK130257.1 Homo sapiens cDNA FLJ26747 fis, clone PRS01488
AK000227.1 Homo sapiens cDNA FLJ20220 fis, clone COLF3372 PA
AK001253.1 Homo sapiens cDNA FLJ10391 fis, clone NT2RM4000139, moderately similar to R.norvegicus trg mRNA P
CR749492.1 Homo sapiens mRNA; cDNA DKFZp781A1532 (from clone DKFZp781A1532) PA
NM_014689.2 Homo sapiens dedicator of cytokinesis 10 (DOCK10), mRNA PA
AF250396.1 Homo sapiens dopamine receptor interacting protein 2 (DRIP2) mRNA, partial cds PA
AB074179.1 Homo sapiens primary neuroblastoma cDNA, clone:Nbla10300, full insert sequence P
BC015018.1 Homo sapiens dedicator of cytokinesis 10, mRNA (cDNA clone IMAGE:3922744), complete cds PA
AK307914.1 Homo sapiens cDNA, FLJ97862 P
EU236710.2 Homo sapiens DOCK10.2 (DOCK10.2) mRNA, complete cds P
AK293879.1 Homo sapiens cDNA FLJ59487 complete cds, highly similar to Dedicator of cytokinesis protein 10 PA
AK293847.1 Homo sapiens cDNA FLJ59486 complete cds, highly similar to Dedicator of cytokinesis protein 10 P

EST sequences (10 of 158) [Show all sequences]

R16401.1 Clone IMAGE:129292 mixed 5' read
AA994322.1 Clone IMAGE:1628120 mixed 3' read
R18401.1 Clone IMAGE:31145 brain 5' read P
BX100241.1 Clone IMAGp998F02150_;_IMAGE:31145 brain A
BX105860.1 Clone IMAGp998M045715_;_IMAGE:2306475 uncharacterized tissue P
AI241684.1 Clone IMAGE:1977441 brain 3' read A
R42464.1 Clone IMAGE:31145 brain 3' read A
AI653069.1 Clone IMAGE:2306475 uncharacterized tissue 3' read P
AI819454.1 Clone IMAGE:2411278 lymph node 3' read A
CB529937.1 Clone UI-H-FT2-bji-h-09-0-UI lung 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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