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UGID:680454     UniGene Hs.465295     Homo sapiens (human)   LMAN1
Lectin, mannose-binding, 1 (LMAN1)

Human protein-coding gene LMAN1. Represented by 670 ESTs from 297 cDNA libraries. Corresponds to reference sequence NM_005570.3. [UniGene 680454 - Hs.465295]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_005561.1 LMAN1 gene product H. sapiens 100.0 509
XP_001143039.1 PREDICTED: protein ERGIC-53 isoform 2 P. troglodytes 99.8 509
NP_081676.1 Lman1 gene product M. musculus 95.2 516
NP_001080950.2 lectin, mannose-binding, 1 precursor X. laevis 78.4 481
XP_688661.4 PREDICTED: protein ERGIC-53 D. rerio 75.4 490
NP_524776.1 ergic53, isoform A D. melanogaster 60.5 327
NP_492548.1 Protein ILE-1 C. elegans 55.3 300
Other hits (2 of 32) [Show all]SpeciesId(%)Len(aa)
XP_001088053.1 PREDICTED: protein ERGIC-53 isoform 2 M. mulatta 98.6 509
XP_003914480.1 PREDICTED: protein ERGIC-53 P. anubis 98.6 509

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; embryonic tissue; uterus; mixed; uncharacterized tissue; liver; adrenal gland; cervix; trachea; eye; kidney; vascular; testis; mammary gland; bone marrow; lung; intestine; ovary; pharynx; thymus; parathyroid; connective tissue; blood; ear; skin; pancreas; prostate; thyroid; muscle; stomach; esophagus; heart; bone; mouth; ascites; lymph node; bladder; pineal gland; spleen; adipose tissue; pituitary gland; lymph; amniotic fluid; umbilical cord
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 18
Map position: 18q21.3-q22
UniSTS entry: Chr 18 WI-11993 [Map Viewer]
UniSTS entry: Chr 18 RH47264 [Map Viewer]
UniSTS entry: Chr 18 RH48271 [Map Viewer]
UniSTS entry: Chr 18 D18S896E [Map Viewer]
UniSTS entry: Chr 18 STS-U09716
UniSTS entry: Chr 18 SHGC-12001 [Map Viewer]
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

NM_005570.3 Homo sapiens lectin, mannose-binding, 1 (LMAN1), mRNA PA
AK223208.1 Homo sapiens mRNA for lectin, mannose-binding, 1 precursor variant, clone: SPL01860 PA
U09716.1 Human mannose-specific lectin (MR60) mRNA, complete cds P
AK025773.1 Homo sapiens cDNA: FLJ22120 fis, clone HEP18874 A
AK225111.1 Homo sapiens mRNA for lectin, mannose-binding, 1 precursor variant, clone: CAS11249 PA
AK225108.1 Homo sapiens mRNA for lectin, mannose-binding, 1 precursor variant, clone: CAS10958 PA
AK312869.1 Homo sapiens cDNA, FLJ93313, highly similar to Homo sapiens lectin, mannose-binding, 1 (LMAN1), mRNA P
BC032330.1 Homo sapiens lectin, mannose-binding, 1, mRNA (cDNA clone MGC:40275 IMAGE:5167524), complete cds PA
X71661.1 H.sapiens ERGIC-53 mRNA P
AK301244.1 Homo sapiens cDNA FLJ57897 complete cds, highly similar to ERGIC-53 protein precursor P
BC017858.1 Homo sapiens lectin, mannose-binding, 1, mRNA (cDNA clone IMAGE:4277970), partial cds PA
BC008401.1 Homo sapiens lectin, mannose-binding, 1, mRNA (cDNA clone IMAGE:4295261), with apparent retained intron PA

EST sequences (10 of 670) [Show all sequences]

AA984971.1 Clone IMAGE:1576772 spleen 3' read A
AA987781.1 Clone IMAGE:1588832 kidney 3' read P
AA994382.1 Clone IMAGE:1625894 mixed 3' read P
AI002960.1 Clone IMAGE:1699521 kidney 3' read A
AI003745.1 Clone IMAGE:392124 pineal gland 3' read A
AI027058.1 Clone IMAGE:1649506 parathyroid 3' read A
AI061097.1 Clone IMAGE:1699757 kidney 3' read A
AI074164.1 Clone IMAGE:1637196 kidney 3' read A
AI075150.1 Clone IMAGE:1672908 mixed 3' read PA
AI079899.1 Clone IMAGE:1659886 embryonic tissue 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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