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UGID:680130     UniGene Hs.464971     Homo sapiens (human)   PIK3C3
Phosphatidylinositol 3-kinase, catalytic subunit type 3 (PIK3C3)

Human protein-coding gene PIK3C3. Represented by 196 ESTs from 117 cDNA libraries. Corresponds to reference sequence NM_002647.2. [UniGene 680130 - Hs.464971]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001142812.1 PREDICTED: uncharacterized protein LOC455385 isoform 3 P. troglodytes 100.0 886
NP_002638.2 PIK3C3 gene product H. sapiens 100.0 886
XP_001082892.1 PREDICTED: phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 1 M. mulatta 99.9 886
XP_547599.3 PREDICTED: phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 2 C. lupus familiaris 99.9 886
XP_001497818.1 PREDICTED: phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 1 E. caballus 99.8 886
NP_001092537.1 PIK3C3 gene product B. taurus 99.8 886
XP_004020459.1 PREDICTED: phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 1 O. aries 99.8 886
XP_002713503.1 PREDICTED: catalytic phosphatidylinositol 3-kinase 3 O. cuniculus 99.8 884
NP_852079.2 Pik3c3 gene product M. musculus 99.5 886
NP_001086836.1 phosphatidylinositol 3-kinase catalytic subunit type 3 X. laevis 95.0 885
NP_001017550.2 pik3c3 gene product D. rerio 90.1 719
NP_477133.1 phosphotidylinositol 3 kinase 59F D. melanogaster 66.7 943
XP_001689631.1 VPS34-like PI-3-kinase C. reinhardtii 61.1 259
XP_965796.1 hypothetical protein NCU00656 N. crassa 58.9 394
NP_001020953.1 Protein VPS-34, isoform b C. elegans 56.2 313
NP_176251.1 phosphatidylinositol 3-kinase VPS34 A. thaliana 56.0 593
NP_013341.1 phosphatidylinositol 3-kinase VPS34 S. cerevisiae 55.0 347
Other hits (2 of 52) [Show all]SpeciesId(%)Len(aa)
NP_075247.1 Pik3c3 gene product R. norvegicus 99.4 886
XP_003914379.1 PREDICTED: LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase catalytic subunit type 3 P. anubis 99.3 929

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; embryonic tissue; liver; uncharacterized tissue; vascular; eye; parathyroid; bone marrow; prostate; muscle; spleen; pancreas; intestine; mouth; blood; pharynx; thymus; skin; larynx; connective tissue; mixed; kidney; uterus; placenta; lung; bone; stomach; heart; spinal cord; ovary; ganglia; umbilical cord; adipose tissue; lymph node; mammary gland; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 18
Map position: 18q12.3
UniSTS entry: Chr 18 SHGC-35582 [Map Viewer]
UniSTS entry: Chr 18 RH74915
UniSTS entry: Chr 18 RH91807
UniSTS entry: Chr 1 D11S2560
UniSTS entry: Chr 1 D15S1477
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

BC053651.1 Homo sapiens phosphoinositide-3-kinase, class 3, mRNA (cDNA clone MGC:61518 IMAGE:5517878), complete cds PA
NM_002647.2 Homo sapiens phosphatidylinositol 3-kinase, catalytic subunit type 3 (PIK3C3), mRNA PA
Z46973.1 H.sapiens mRNA for phosphatidylinositol 3-kinase PA
AK022653.1 Homo sapiens cDNA FLJ12591 fis, clone NT2RM4001313, moderately similar to PHOSPHATIDYLINOSITOL 3-KINASE VPS34-LIKE (EC 2.7.1.137) P
AK308364.1 Homo sapiens cDNA, FLJ98312 P
BC033004.2 Homo sapiens phosphoinositide-3-kinase, class 3, mRNA (cDNA clone MGC:26376 IMAGE:4823337), complete cds PA
AK090567.1 Homo sapiens cDNA FLJ33248 fis, clone ASTRO2005008, highly similar to Rattus norvegicus mRNA for phosphatidylinositol 3-kinase P
AK298517.1 Homo sapiens cDNA FLJ55742 complete cds, highly similar to Phosphatidylinositol 3-kinase catalyticsubunit type 3 (EC 2.7.1.137) PA
BC010388.1 Homo sapiens phosphoinositide-3-kinase, class 3, mRNA (cDNA clone IMAGE:4132704), with apparent retained intron PA

EST sequences (10 of 196) [Show all sequences]

AA968906.1 Clone IMAGE:1574609 kidney 3' read A
AI004748.1 Clone IMAGE:1625332 embryonic tissue 3' read
AA947520.1 Clone IMAGE:1590109 kidney 3' read PA
AI078676.1 Clone IMAGE:1667938 parathyroid 3' read A
AI089871.1 Clone IMAGE:1686461 brain 3' read
AI130770.1 Clone IMAGE:1709415 heart 3' read PA
CB055190.1 Clone IMAGE:3291717 brain 3' read A
CB055191.1 Clone IMAGE:3291717 brain 5' read A
BX101437.1 Clone IMAGp998D015195_;_IMAGE:2106576 brain
AI083908.1 Clone IMAGE:1751119 brain 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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