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UGID:677084     UniGene Hs.461925     Homo sapiens (human)   RPA1
Replication protein A1, 70kDa (RPA1)

Human protein-coding gene RPA1. Represented by 441 ESTs from 224 cDNA libraries. Corresponds to reference sequence NM_002945.3. [UniGene 677084 - Hs.461925]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_002936.1 RPA1 gene product H. sapiens 100.0 615
XP_511254.3 PREDICTED: replication protein A 70 kDa DNA-binding subunit P. troglodytes 99.8 615
NP_080929.1 Rpa1 gene product M. musculus 91.8 622
NP_001081585.1 replication protein A 70 kDa DNA-binding subunit X. laevis 80.6 604
NP_956105.2 rpa1 gene product D. rerio 71.3 599
NP_524274.1 replication protein A 70 D. melanogaster 54.5 501
NP_973433.1 replication factor A1 A. thaliana 45.9 181
XP_961333.1 replication factor-A protein 1 N. crassa 45.4 335
Other hits (2 of 47) [Show all]SpeciesId(%)Len(aa)
XP_003912118.1 PREDICTED: replication protein A 70 kDa DNA-binding subunit P. anubis 99.0 615
XP_002800290.1 PREDICTED: replication protein A 70 kDa DNA-binding subunit-like, partial M. mulatta 98.7 475

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; embryonic tissue; placenta; testis; larynx; amniotic fluid; adrenal gland; bladder; uncharacterized tissue; ovary; eye; intestine; prostate; kidney; lung; pharynx; uterus; stomach; mammary gland; mixed; liver; skin; thyroid; thymus; bone; heart; blood; muscle; tonsil; cervix; trachea; ascites; connective tissue; lymph node; lymph; mouth; spleen; vascular; bone marrow; pancreas; umbilical cord
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17p13.3
UniSTS entry: Chr 17 G62062
UniSTS entry: Chr 17 D17S1427E [Map Viewer]
UniSTS entry: RH93214
UniSTS entry: Chr 17 RH17723 [Map Viewer]
UniSTS entry: Chr 17 G29183
UniSTS entry: Chr 17 RH76450
UniSTS entry: Chr 17 WI-20954 [Map Viewer]
UniSTS entry: Chr 17 RH18502 [Map Viewer]
UniSTS entry: Chr 17 RPA1_1165
UniSTS entry: Chr 1 D11S3114
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

M63488.1 Human replication protein A 70kDa subunit mRNA complete cds P
AF167994.1 Homo sapiens MSTP075 (MST075) mRNA, complete cds A
NM_002945.3 Homo sapiens replication protein A1, 70kDa (RPA1), mRNA P
AB209732.1 Homo sapiens mRNA for replication protein A1, 70kDa variant protein P
BC018126.1 Homo sapiens replication protein A1, 70kDa, mRNA (cDNA clone MGC:9195 IMAGE:3912837), complete cds PA
AK289704.1 Homo sapiens cDNA FLJ75577 complete cds, highly similar to Homo sapiens replication protein A1, 70kDa (RPA1), mRNA P

EST sequences (10 of 441) [Show all sequences]

AA991598.1 Clone IMAGE:1609774 mammary gland 3' read A
T05740.1 Clone HFBDF68 brain P
AI052509.1 Clone IMAGE:1676574 embryonic tissue 3' read PA
AA946941.1 Clone IMAGE:1590167 kidney 3' read A
AI075287.1 Clone IMAGE:1671137 uncharacterized tissue 3' read A
AI091214.1 Clone IMAGE:1566928 mixed 3' read
AI092182.1 Clone IMAGE:1694362 heart 3' read A
R22935.1 Clone IMAGE:131004 placenta 3' read
R23039.1 Clone IMAGE:131004 placenta 5' read
AI141113.1 Clone IMAGE:1739418 lung 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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