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UGID:676155     UniGene Hs.460996     Homo sapiens (human)   TRADD
TNFRSF1A-associated via death domain (TRADD)

Human protein-coding gene TRADD. Represented by 161 ESTs from 92 cDNA libraries. Corresponds to reference sequence NM_003789.3. [UniGene 676155 - Hs.460996]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_511022.3 PREDICTED: tumor necrosis factor receptor type 1-associated DEATH domain protein P. troglodytes 100.0 311
NP_003780.1 TRADD gene product H. sapiens 100.0 311
NP_001028333.1 tumor necrosis factor receptor type 1-associated DEATH domain protein M. musculus 82.6 309
NP_571682.1 tradd gene product D. rerio 47.9 169
Other hits (2 of 18) [Show all]SpeciesId(%)Len(aa)
XP_003917062.1 PREDICTED: tumor necrosis factor receptor type 1-associated DEATH domain protein isoform 1 P. anubis 98.7 307
XP_002802576.1 PREDICTED: tumor necrosis factor receptor type 1-associated DEATH domain protein-like M. mulatta 98.0 247

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lung; brain; kidney; mixed; eye; placenta; pancreas; intestine; uncharacterized tissue; heart; spleen; lymph node; mammary gland; prostate; uterus; esophagus; liver; thyroid; ovary; embryonic tissue; mouth; trachea; skin; testis; bone marrow; lymph; thymus; parathyroid; tonsil; adipose tissue; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16q22
UniSTS entry: Chr 16 RH69054 [Map Viewer]
UniSTS entry: Chr 16 RH78922 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

BT006934.1 Homo sapiens TNFRSF1A-associated via death domain mRNA, complete cds P
NM_003789.3 Homo sapiens TNFRSF1A-associated via death domain (TRADD), mRNA PA
BC004491.2 Homo sapiens TNFRSF1A-associated via death domain, mRNA (cDNA clone MGC:11078 IMAGE:3689007), complete cds PA
AK315654.1 Homo sapiens cDNA, FLJ96745, Homo sapiens TNFRSF1A-associated via death domain (TRADD),transcript variant 1, mRNA P
AK090673.1 Homo sapiens cDNA FLJ33354 fis, clone BRACE2005124, highly similar to Tumor necrosis factor receptor type1-associated DEATH domain protein P
AK301593.1 Homo sapiens cDNA FLJ54928 complete cds, weakly similar to Tumor necrosis factor receptor type1-associated DEATH domain protein
L41690.1 Homo sapiens TNF receptor-1 associated protein (TRADD) mRNA, 3' end of cds P

EST sequences (10 of 161) [Show all sequences]

AA972629.1 Clone IMAGE:1585038 lung 3' read P
AI087997.1 Clone IMAGE:1567170 mixed 3' read P
AA907094.1 Clone IMAGE:1522365 lung 3' read P
AI131201.1 Clone IMAGE:1709323 heart 3' read P
AI144401.1 Clone IMAGE:1706139 heart 3' read P
CB054809.1 Clone IMAGE:3291677 brain 3' read P
CB054810.1 Clone IMAGE:3291677 brain 5' read P
AI241163.1 Clone IMAGE:1868122 kidney 3' read P
AI318396.1 Clone IMAGE:1912254 intestine 3' read P
AI344303.1 Clone IMAGE:2062757 intestine 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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