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UGID:675457     UniGene Hs.460298     Homo sapiens (human)   POLR3E
Polymerase (RNA) III (DNA directed) polypeptide E (80kD) (POLR3E)

Human protein-coding gene POLR3E. Represented by 532 ESTs from 260 cDNA libraries. Corresponds to 6 reference sequences (different isoforms). [UniGene 675457 - Hs.460298]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003960669.1 PREDICTED: DNA-directed RNA polymerase III subunit RPC5-like isoform 2 H. sapiens 100.0 707
XP_003916703.1 PREDICTED: DNA-directed RNA polymerase III subunit RPC5 isoform 1 P. anubis 99.9 708
XP_001086444.2 PREDICTED: DNA-directed RNA polymerase III subunit RPC5 M. mulatta 99.5 672
NP_079574.2 Polr3e gene product M. musculus 96.8 709
NP_001085230.1 polymerase (RNA) III (DNA directed) polypeptide E (80kD) X. laevis 78.0 700
NP_997919.1 polr3e gene product D. rerio 76.4 693
Other hits (2 of 25) [Show all]SpeciesId(%)Len(aa)
XP_511201.4 PREDICTED: DNA-directed RNA polymerase III subunit RPC5 P. troglodytes 99.0 729
XP_003362772.1 PREDICTED: DNA-directed RNA polymerase III subunit RPC5 E. caballus 99.0 710

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; lung; uncharacterized tissue; intestine; cervix; muscle; stomach; mouth; skin; liver; mammary gland; uterus; prostate; thyroid; pancreas; vascular; thymus; trachea; heart; lymph node; connective tissue; bladder; eye; mixed; blood; embryonic tissue; placenta; ovary; esophagus; kidney; ascites; larynx; nerve; bone; spleen; bone marrow; adrenal gland; lymph; amniotic fluid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16p12.2
UniSTS entry: Chr 16 STS-W72446 [Map Viewer]
UniSTS entry: Chr 16 RH80971
UniSTS entry: Chr 1 D10S16
UniSTS entry: Chr 1 D1S1425
UniSTS entry: Chr 16 POLR3E_8065
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

AK130661.1 Homo sapiens cDNA FLJ27151 fis, clone SYN00523 P
AK001371.1 Homo sapiens cDNA FLJ10509 fis, clone NT2RP2000617 P
NM_018119.3 Homo sapiens polymerase (RNA) III (DNA directed) polypeptide E (80kD) (POLR3E), transcript variant 1, mRNA PA
AB040885.1 Homo sapiens mRNA for KIAA1452 protein, partial cds P
AK222789.1 Homo sapiens mRNA for polymerase (RNA) III (DNA directed) polypeptide E variant, clone: HEP02371 PA
AK222671.1 Homo sapiens mRNA, polymerase (RNA) III (DNA directed) polypeptide E variant, clone: CBR03318 PA
AK023160.1 Homo sapiens cDNA FLJ13098 fis, clone NT2RP3002244 P
AK023231.1 Homo sapiens cDNA FLJ13169 fis, clone NT2RP3003805 P
AK026645.1 Homo sapiens cDNA: FLJ22992 fis, clone KAT11904 PA
BC000285.1 Homo sapiens polymerase (RNA) III (DNA directed) polypeptide E (80kD), mRNA (cDNA clone MGC:957 IMAGE:3356711), complete cds PA
AK300735.1 Homo sapiens cDNA FLJ59434 complete cds, highly similar to DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) P
AK293300.1 Homo sapiens cDNA FLJ55674 complete cds, highly similar to DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) P
AK296813.1 Homo sapiens cDNA FLJ59568 complete cds, highly similar to DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) P
NM_001258035.1 Homo sapiens polymerase (RNA) III (DNA directed) polypeptide E (80kD) (POLR3E), transcript variant 3, mRNA PA
NM_001258033.1 Homo sapiens polymerase (RNA) III (DNA directed) polypeptide E (80kD) (POLR3E), transcript variant 2, mRNA PA
NM_001258036.1 Homo sapiens polymerase (RNA) III (DNA directed) polypeptide E (80kD) (POLR3E), transcript variant 5, mRNA PA
NM_001258034.1 Homo sapiens polymerase (RNA) III (DNA directed) polypeptide E (80kD) (POLR3E), transcript variant 4, mRNA PA
NR_047581.1 Homo sapiens polymerase (RNA) III (DNA directed) polypeptide E (80kD) (POLR3E), transcript variant 6, non-coding RNA PA
AY092085.1 Homo sapiens RNA polymerase III 80 kDa subunit RPC5 mRNA, complete cds P

EST sequences (10 of 532) [Show all sequences]

R16421.1 Clone IMAGE:129326 mixed 5' read
AI004165.1 Clone IMAGE:1631797 mammary gland 3' read A
AI017646.1 Clone IMAGE:1635934 kidney 3' read A
R18902.1 Clone IMAGE:32517 brain 5' read
AI094731.1 Clone IMAGE:1686187 brain 3' read A
AA864933.1 Clone IMAGE:1469617 uncharacterized tissue 3' read A
AI190446.1 Clone IMAGE:1733233 heart 3' read A
AI271279.1 Clone IMAGE:1997732 mammary gland 3' read
CB134238.1 Clone B2N807043-1-D11 brain 5' read P
CB142148.1 Clone L11SNU354s1-16-F12 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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