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UGID:627235     UniGene Hs.458272     Homo sapiens (human)   MPO
Myeloperoxidase (MPO)

Human protein-coding gene MPO. Represented by 433 ESTs from 92 cDNA libraries. EST representation biased toward blood; leukemia; adult. Corresponds to reference sequence NM_000250.1. [UniGene 627235 - Hs.458272]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000241.1 MPO gene product H. sapiens 100.0 744
XP_001162602.2 PREDICTED: myeloperoxidase P. troglodytes 99.9 744
NP_034954.2 Mpo gene product M. musculus 89.4 717
NP_001081848.1 eosinophil peroxidase precursor X. laevis 64.8 704
NP_997944.1 mpx gene product D. rerio 55.1 697
NP_523891.2 peroxidasin, isoform A D. melanogaster 47.3 201
NP_509834.1 Protein PXN-2 C. elegans 46.4 207
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
XP_001103896.2 PREDICTED: myeloperoxidase M. mulatta 97.7 744
XP_003912859.1 PREDICTED: myeloperoxidase P. anubis 97.6 744

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: blood [show more like this]
leukemia [show more like this]
adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: blood; brain; bone marrow; mixed; placenta; kidney; thyroid; uncharacterized tissue; bone; lung; lymph node; eye; embryonic tissue; thymus; testis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17q23.1
UniSTS entry: Chr 17 D17S1716
UniSTS entry: Chr 17 STS-M19507
UniSTS entry: Chr 17 D17S1975 [Map Viewer]
UniSTS entry: Chr 17 GDB:196134
UniSTS entry: Chr 17 GDB:178575
UniSTS entry: Chr 17 RH45018
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

NM_000250.1 Homo sapiens myeloperoxidase (MPO), nuclear gene encoding mitochondrial protein, mRNA P
M19507.1 Human myeloperoxidase mRNA, complete cds P
J02694.1 Human myeloperoxidase mRNA, complete cds P
BC130476.1 Homo sapiens myeloperoxidase, mRNA (cDNA clone MGC:163348 IMAGE:40146507), complete cds P
X04876.1 Human mRNA for myeloperoxidase (EC 1.11.1.7) P
S56200.1 myeloperoxidase [human, monocytic leukemia cell line SKM-1, mRNA Partial, 2238 nt] P

EST sequences (10 of 433) [Show all sequences]

AA954392.1 Clone IMAGE:1564907 mixed 3' read A
AA954479.1 Clone IMAGE:1562325 mixed 3' read
AA954480.1 Clone IMAGE:1562327 mixed 3' read
AI052829.1 Clone IMAGE:1675073 mixed 3' read P
AI056254.1 Clone IMAGE:1673143 mixed 3' read A
BX106821.1 Clone IMAGp998K05123_;_IMAGE:125308 mixed A
AI670013.1 Clone IMAGE:2345834 thymus 3' read A
AI688563.1 Clone IMAGE:2330543 mixed 3' read
AI803222.1 Clone IMAGE:2066910 embryonic tissue 3' read P
AW075890.1 Clone IMAGE:2573181 blood 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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