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UGID:619073     UniGene Hs.450110     Homo sapiens (human)   TMPRSS11A
Transmembrane protease, serine 11A (TMPRSS11A)

Human protein-coding gene TMPRSS11A. Represented by 18 ESTs from 10 cDNA libraries. EST representation biased toward esophageal tumor. Corresponds to 2 reference sequences (different isoforms). [UniGene 619073 - Hs.450110]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_872412.3 TMPRSS11A gene product H. sapiens 100.0 420
XP_526606.4 PREDICTED: transmembrane protease serine 11A P. troglodytes 99.8 417
NP_001028405.1 Tmprss11a gene product M. musculus 67.0 384
Other hits (2 of 15) [Show all]SpeciesId(%)Len(aa)
XP_001109001.2 PREDICTED: transmembrane protease serine 11A-like M. mulatta 95.0 417
XP_003898883.1 PREDICTED: transmembrane protease serine 11A P. anubis 93.3 386

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: esophageal tumor [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mouth; trachea; esophagus; larynx; muscle; brain; uncharacterized tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q13.2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

AF071882.1 Homo sapiens esophageal cancer susceptibility protein (ECRG1) mRNA, complete cds PA
NM_182606.3 Homo sapiens transmembrane protease, serine 11A (TMPRSS11A), transcript variant 1, mRNA P
AK131518.1 Homo sapiens cDNA FLJ16745 fis, clone CTONG2016942, weakly similar to Homo sapiens serine protease DESC1 (DESC1) mRNA P
AY498712.1 Homo sapiens epidermal type II transmembrane serine protease (HESP) mRNA, complete cds PA
BC111796.1 Homo sapiens transmembrane protease, serine 11A, mRNA (cDNA clone MGC:133183 IMAGE:40026103), complete cds P
AK292950.1 Homo sapiens cDNA FLJ78099 complete cds P
NM_001114387.1 Homo sapiens transmembrane protease, serine 11A (TMPRSS11A), transcript variant 2, mRNA P

EST sequences (10 of 18) [Show all sequences]

BX490784.1 Clone DKFZp686N0790 muscle 5' read P
CV318544.1 larynx
DA446088.1 Clone CTONG2016942 mouth 5' read P
DA460068.1 Clone CTONG3006739 mouth 5' read P
DB013449.1 Clone TESOP2002017 esophagus 5' read P
DB018102.1 Clone TESOP2007787 esophagus 5' read P
DA762936.1 Clone NTONG2002822 mouth 5' read P
DB313977.1 Clone CTONG2016942 mouth 3' read
DB207362.1 Clone TRACH2019933 trachea 5' read P
DB220335.1 Clone TRACH3010645 trachea 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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