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UGID:241186     UniGene Hs.446149     Homo sapiens (human)   LDHB
Lactate dehydrogenase B (LDHB)

Human protein-coding gene LDHB. Represented by 4010 ESTs from 508 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 241186 - Hs.446149]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003906147.1 PREDICTED: L-lactate dehydrogenase B chain P. anubis 100.0 333
NP_001092031.1 LDHB gene product P. troglodytes 100.0 333
NP_001167568.1 LDHB gene product H. sapiens 100.0 333
NP_001239093.1 L-lactate dehydrogenase B chain C. lupus familiaris 100.0 333
NP_001182636.1 L-lactate dehydrogenase B chain O. cuniculus 100.0 333
NP_001138583.1 LDHB gene product E. caballus 100.0 332
XP_001117178.1 PREDICTED: l-lactate dehydrogenase B chain M. mulatta 99.7 369
NP_001106758.1 L-lactate dehydrogenase B chain S. scrofa 99.7 333
NP_776525.1 LDHB gene product B. taurus 99.7 333
XP_004006841.1 PREDICTED: L-lactate dehydrogenase B chain isoform 1 O. aries 99.7 333
NP_032518.1 Ldhb gene product M. musculus 99.4 333
NP_001081050.1 L-lactate dehydrogenase A chain X. laevis 89.8 333
NP_571322.1 ldhba gene product D. rerio 88.9 333
NP_496503.1 Protein LDH-1 C. elegans 75.8 331
NP_476581.1 Ecdysone-inducible gene L3, isoform A D. melanogaster 71.6 331
NP_193459.1 L-lactate dehydrogenase A. thaliana 60.6 343
Other hits (2 of 36) [Show all]SpeciesId(%)Len(aa)
NP_036727.1 Ldhb gene product R. norvegicus 99.4 333
NP_001028150.1 LDHB gene product M. domestica 98.2 333

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; skin; embryonic tissue; uterus; eye; testis; lung; muscle; uncharacterized tissue; kidney; mixed; liver; intestine; ovary; lymph; bladder; pancreas; pharynx; blood; prostate; bone marrow; heart; mammary gland; bone; tonsil; vascular; cervix; adrenal gland; salivary gland; ascites; mouth; connective tissue; spleen; umbilical cord; adipose tissue; stomach; parathyroid; pituitary gland; larynx; ear; thymus; thyroid; lymph node; spinal cord; nerve; epididymis; amniotic fluid; trachea; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12p12.2-p12.1
UniSTS entry: Chr X G07018
UniSTS entry: Chr 12 RH15605
UniSTS entry: Chr X SHGC-132102
UniSTS entry: Chr 12 SHGC-12682
UniSTS entry: Chr 12 D13S838E
UniSTS entry: LDHB
UniSTS entry: Chr 12 GDB:384749
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

AK129881.1 Homo sapiens cDNA FLJ26371 fis, clone HRT06187, highly similar to L-lactate dehydrogenase H chain (EC 1.1.1.27) P
NM_002300.6 Homo sapiens lactate dehydrogenase B (LDHB), transcript variant 1, mRNA PA
BC071860.1 Homo sapiens lactate dehydrogenase B, mRNA (cDNA clone MGC:88529 IMAGE:4902461), complete cds PA
BT019765.1 Homo sapiens lactate dehydrogenase B mRNA, complete cds P
BT019764.1 Homo sapiens lactate dehydrogenase B mRNA, complete cds P
AY189689.1 Homo sapiens transformation-related protein 5 mRNA, complete cds PA
BC002362.1 Homo sapiens lactate dehydrogenase B, mRNA (cDNA clone MGC:8627 IMAGE:2961445), complete cds PA
BC015122.1 Homo sapiens lactate dehydrogenase B, mRNA (cDNA clone MGC:24208 IMAGE:3685985), complete cds PA
AK312328.1 Homo sapiens cDNA, FLJ92640, Homo sapiens lactate dehydrogenase B (LDHB), mRNA P
BC022835.1 Homo sapiens lactate dehydrogenase B, mRNA (cDNA clone IMAGE:4867637) PA
D28368.1 Homo sapiens mRNA for lactate dehydrogenase H chain, 5'UTR region
Y00711.1 Human mRNA for lactate dehydrogenase B (LDH-B) P
NM_001174097.1 Homo sapiens lactate dehydrogenase B (LDHB), transcript variant 2, mRNA PA

EST sequences (10 of 4010) [Show all sequences]

R14149.1 Clone IMAGE:28508 brain 5' read P
R14374.1 Clone IMAGE:28721 brain 5' read
AA970550.1 Clone IMAGE:1573886 kidney 3' read A
AA970679.1 Clone IMAGE:1579010 mixed 3' read A
AA974410.1 Clone IMAGE:1587442 uncharacterized tissue 3' read PA
AA975762.1 Clone IMAGE:1591147 kidney 3' read P
AA978102.1 Clone IMAGE:1578507 mixed 3' read A
AA995510.1 Clone IMAGE:1606094 kidney 3' read PA
AI000455.1 Clone IMAGE:1614146 uncharacterized tissue 3' read A
AA902716.1 Clone IMAGE:1519442 uncharacterized tissue 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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