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UGID:236239     UniGene Hs.441202     Homo sapiens (human)   GFRA2
GDNF family receptor alpha 2 (GFRA2)

Human protein-coding gene GFRA2. Represented by 82 ESTs from 43 cDNA libraries. EST representation biased toward infant. Corresponds to 3 reference sequences (different isoforms). [UniGene 236239 - Hs.441202]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001486.4 GFRA2 gene product H. sapiens 100.0 463
XP_001105178.2 PREDICTED: GDNF family receptor alpha-2-like M. mulatta 100.0 317
XP_001146351.2 PREDICTED: GDNF family receptor alpha-2 P. troglodytes 100.0 317
NP_032141.2 GDNF family receptor alpha-2 precursor M. musculus 97.4 463
XP_693326.4 PREDICTED: GDNF family receptor alpha-2-like D. rerio 67.6 392
Other hits (2 of 18) [Show all]SpeciesId(%)Len(aa)
XP_851478.2 PREDICTED: GDNF family receptor alpha-2 C. lupus familiaris 98.3 358
XP_004004261.1 PREDICTED: GDNF family receptor alpha-2 isoform 1 O. aries 97.6 463

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: infant [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; eye; uncharacterized tissue; placenta; muscle; mixed; intestine; ovary; testis; embryonic tissue; heart; bone; prostate; connective tissue; kidney
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8p21.3
UniSTS entry: Chr 8 A003B30
UniSTS entry: Chr 8 SHGC-31819 [Map Viewer]
UniSTS entry: Chr 8 D8S1417E [Map Viewer]
UniSTS entry: Chr 8 WI-19670 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

BC041688.1 Homo sapiens GDNF family receptor alpha 2, mRNA (cDNA clone MGC:48679 IMAGE:5729102), complete cds PA
AY326396.1 Homo sapiens glial cell line-derived neurotrophic factor family receptor alpha2c mRNA, complete cds P
NM_001495.4 Homo sapiens GDNF family receptor alpha 2 (GFRA2), transcript variant 1, mRNA PA
AY941828.1 Homo sapiens glial cell line-derived neurotrophic factor family receptor alpha2b mRNA, complete cds P
AK299623.1 Homo sapiens cDNA FLJ53091 complete cds, highly similar to GDNF family receptor alpha-2 precursor P
NM_001165039.1 Homo sapiens GDNF family receptor alpha 2 (GFRA2), transcript variant 3, mRNA PA
NM_001165038.1 Homo sapiens GDNF family receptor alpha 2 (GFRA2), transcript variant 2, mRNA PA
AF002700.1 Homo sapiens GDNF family receptor alpha 2 (GFRalpha2) mRNA, complete cds P
U97145.1 Homo sapiens RET ligand 2 (RETL2) mRNA, complete cds PA
U93703.1 Human glial cell line-derived neurotrophic factor receptor beta (GDNFR-beta) mRNA, complete cds P

EST sequences (10 of 82) [Show all sequences]

BX101753.1 Clone IMAGp998D10121_;_IMAGE:124377 mixed P
AI215061.1 Clone IMAGE:1838796 testis 3' read A
AI266492.1 Clone IMAGE:1891834 placenta 3' read P
AI676143.1 Clone IMAGE:2314350 prostate 3' read P
CB994592.1 Clone IMAGE:30330969 placenta 5' read
CB996522.1 Clone IMAGE:30339230 placenta 5' read
CB998316.1 Clone IMAGE:30349275 placenta 5' read
BX392384.2 Clone CS0DD003YL06 uncharacterized tissue 3' read
BX333936.2 Clone CS0DD003YL06 uncharacterized tissue 5' read
AI870650.1 Clone IMAGE:2431776 brain 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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